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ONTOLOGY REPORT - ANNOTATIONS

Term:endodermal cell fate specification
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Accession:GO:0001714 term browser browse the term
Definition:The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
Synonyms:exact_synonym: endoderm cell fate specification


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endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21245162) TreeGrafter
MGI		 PMID:21245162 GO_REF:0000118 NCBI chr23:16,476,498...16,512,406
Ensembl chr23:16,506,032...16,511,527 		JBrowse link
G HNF1B HNF1 homeobox B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18635606) Ensembl
MGI		 PMID:18635606 GO_REF:0000107 NCBI chr 9:37,437,992...37,493,200
Ensembl chr 9:37,438,583...37,492,993 		JBrowse link
G NANOG Nanog homeobox acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chr27:37,262,558...37,266,449 JBrowse link
G POU5F1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518
G SOX17 SRY-box transcription factor 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:5,979,092...5,981,504
Ensembl chr29:5,979,261...5,981,124 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:21245162) MGI PMID:21245162 NCBI chr34:14,853,000...14,855,153 JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,738,333...52,739,962
Ensembl chr 3:52,738,366...52,739,755 		JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:35,697,428...35,701,596
Ensembl chr26:35,697,618...35,701,496 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17925
    developmental process 6840
      cellular developmental process 4597
        cell fate specification 105
          endodermal cell fate specification 8
            negative regulation of endodermal cell fate specification 1
            regulation of endodermal cell fate specification + 2
Path 2
Term Annotations click to browse term
  biological_process 17925
    developmental process 6840
      anatomical structure development 6424
        multicellular organism development 5184
          embryo development 1346
            embryonic morphogenesis 702
              gastrulation 217
                formation of primary germ layer 146
                  endoderm formation 64
                    endodermal cell differentiation 53
                      endodermal cell fate commitment 15
                        endodermal cell fate specification 8
                          negative regulation of endodermal cell fate specification 1
                          regulation of endodermal cell fate specification + 2
paths to the root