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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sodium chromate
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Accession:CHEBI:78671 term browser browse the term
Definition:An inorganic sodium salt consisting of sodium and chromate ions in a 2:1 ratio.
Synonyms:exact_synonym: disodium dioxido(dioxo)chromium
 related_synonym: Chromic acid, disodium salt;   Chromium disodium oxide;   Chromiumsodium oxide;   Disodium chromate;   Formula=CrNa2O4;   H2CrO4;   InChI=1S/Cr.2Na.4O/q;2*+1;;;2*-1;   InChIKey=PXLIDIMHPNPGMH-UHFFFAOYSA-N;   SMILES=[Na+].[Na+].[O-][Cr]([O-])(=O)=O;   Sodium chromate(VI)
 xref: CAS:7775-11-3
 xref_mesh: MESH:C028982
 xref: PMID:12020100;   PMID:19839025;   PMID:2753952;   PMID:2799895;   PMID:3009436;   Reaxys:14302947;   Wikipedia:Sodium_chromate


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sodium chromate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase multiple interactions
decreases expression		 ISO MUS81 protein mutant form inhibits the reaction [sodium chromate(VI) results in decreased expression of ATM protein modified form]
[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of ATM protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of ATM protein]		 CTD PMID:28318385 PMID:35643323 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G B2m beta-2 microglobulin increases expression EXP sodium chromate(VI) results in increased expression of B2M protein CTD PMID:2202081 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions		 ISO sodium chromate(VI) results in decreased expression of BAX mRNA
[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of BAX mRNA; [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of BAX protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of BAX protein]		 CTD PMID:14971655 PMID:35643323 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of BBC3 mRNA; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of BBC3 mRNA] CTD PMID:35643323 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions		 ISO sodium chromate(VI) results in increased expression of BCL2 mRNA
[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of BCL2 mRNA; [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of BCL2 protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of BCL2 mRNA]		 CTD PMID:14971655 PMID:35643323 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO sodium chromate(VI) results in decreased expression of BCL2L1 mRNA CTD PMID:14971655 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l11 Bcl2-like 11 multiple interactions ISO [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of BCL2L11 mRNA; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of BCL2L11 mRNA] CTD PMID:35643323 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl2l2 Bcl2-like 2 decreases expression ISO sodium chromate(VI) results in decreased expression of BCL2L2 mRNA CTD PMID:14971655 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Casp3 caspase 3 increases expression
increases activity		 ISO sodium chromate(VI) results in increased expression of CASP3 mRNA
sodium chromate(VI) results in increased activity of CASP3 protein		 CTD PMID:16283527 PMID:19839025 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of CCNB1 protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of CCNB1 protein] CTD PMID:35643323 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of CDK1 protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of CDK1 protein] CTD PMID:35643323 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of CDK2 protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of CDK2 protein] CTD PMID:35643323 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO sodium chromate(VI) results in increased expression of CDKN1A mRNA CTD PMID:16283527 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP Carbon Monoxide inhibits the reaction [CYP1A1 protein results in increased reduction of sodium chromate(VI)]; Carbon Tetrachloride inhibits the reaction [CYP1A1 protein results in increased reduction of sodium chromate(VI)]; CYP1A1 protein binds to and results in increased reduction of sodium chromate(VI) CTD PMID:1903091 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases reduction		 EXP Carbon Monoxide inhibits the reaction [CYP2B1 protein results in increased reduction of sodium chromate(VI)]; Carbon Tetrachloride inhibits the reaction [CYP2B1 protein results in increased reduction of sodium chromate(VI)] CTD PMID:1903091 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP Carbon Monoxide inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)]; Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)]; CYP2E1 protein binds to and results in increased reduction of sodium chromate(VI) CTD PMID:1903091 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO sodium chromate(VI) results in increased expression of DUSP10 mRNA CTD PMID:16283527 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 multiple interactions ISO ERRFI1 protein inhibits the reaction [sodium chromate(VI) results in decreased expression of KRBOX1 protein]; ERRFI1 protein inhibits the reaction [sodium chromate(VI) results in increased expression of UCHL1 protein] CTD PMID:28688920 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression		 ISO MUS81 protein mutant form inhibits the reaction [sodium chromate(VI) results in increased expression of H2AX protein modified form]
[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of H2AX protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of H2AX protein]		 CTD PMID:28318385 PMID:35643323 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression ISO sodium chromate(VI) results in increased expression of HSPD1 protein CTD PMID:19771553 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sodium chromate(VI) results in increased expression of IL1B mRNA]; pyrazolanthrone inhibits the reaction [sodium chromate(VI) results in increased expression of IL1B mRNA] CTD PMID:22547200 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Krbox1 KRAB box domain containing 1 multiple interactions
decreases expression		 ISO ERRFI1 protein inhibits the reaction [sodium chromate(VI) results in decreased expression of KRBOX1 protein] CTD PMID:28688920 NCBI chr 8:121,597,254...121,604,048
Ensembl chr 8:121,597,319...121,604,027 		JBrowse link
G Krt10 keratin 10 increases expression ISO sodium chromate(VI) results in increased expression of KRT10 protein CTD PMID:19771553 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701 		JBrowse link
G Krt16 keratin 16 increases expression ISO sodium chromate(VI) results in increased expression of KRT16 protein CTD PMID:19771553 NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt17 keratin 17 increases expression ISO sodium chromate(VI) results in increased expression of KRT17 protein CTD PMID:19771553 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392 		JBrowse link
G Krt25 keratin 25 increases expression ISO sodium chromate(VI) results in increased expression of KRT25 protein CTD PMID:19771553 NCBI chr10:84,267,399...84,275,025
Ensembl chr10:84,267,399...84,274,965 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 multiple interactions ISO [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of MAD1L1 mRNA; [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of MAD1L1 protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of MAD1L1 mRNA]; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of MAD1L1 protein] CTD PMID:35643323 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 multiple interactions ISO [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of MAD2L1 mRNA; [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of MAD2L1 protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of MAD2L1 mRNA]; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of MAD2L1 protein] CTD PMID:35643323 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sodium chromate(VI) results in increased phosphorylation of MAPK1 protein]
[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of MAPK1 protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of MAPK1 protein]		 CTD PMID:14971655 PMID:35643323 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sodium chromate(VI) results in increased phosphorylation of MAPK3 protein]
[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of MAPK3 protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of MAPK3 protein]		 CTD PMID:14971655 PMID:35643323 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit multiple interactions ISO MUS81 protein mutant form inhibits the reaction [sodium chromate(VI) results in decreased expression of ATM protein modified form]; MUS81 protein mutant form inhibits the reaction [sodium chromate(VI) results in increased expression of H2AX protein modified form] CTD PMID:28318385 NCBI chr 1:202,790,295...202,796,008
Ensembl chr 1:202,790,466...202,795,843 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO sodium chromate(VI) results in increased expression of MYC mRNA CTD PMID:16283527 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sodium chromate(VI) results in increased phosphorylation of NFKB1 protein]; pyrazolanthrone inhibits the reaction [sodium chromate(VI) results in increased phosphorylation of NFKB1 protein] CTD PMID:22547200 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sodium chromate(VI) results in increased expression of NOS2 protein]; pyrazolanthrone inhibits the reaction [sodium chromate(VI) results in increased expression of NOS2 protein] CTD PMID:22547200 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of PCNA protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in decreased expression of PCNA protein] CTD PMID:35643323 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sodium chromate(VI) results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [sodium chromate(VI) results in increased expression of PTGS2 protein] CTD PMID:22547200 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sodium chromate(VI) results in increased phosphorylation of RELA protein]; pyrazolanthrone inhibits the reaction [sodium chromate(VI) results in increased phosphorylation of RELA protein] CTD PMID:22547200 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 multiple interactions ISO [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of SETDB1 protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression of SETDB1 protein] CTD PMID:35643323 NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506 		JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions		 ISO sodium chromate(VI) results in increased expression of TP53 protein
[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of TRP53 protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of TRP53 protein]		 CTD PMID:16283527 PMID:35643323 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txn1 thioredoxin 1 increases oxidation
multiple interactions		 ISO sodium chromate(VI) results in increased oxidation of TXN protein
tris(2-carboxyethyl)phosphine inhibits the reaction [sodium chromate(VI) results in increased oxidation of TXN protein]		 CTD PMID:18328613 PMID:19135121 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txn2 thioredoxin 2 increases oxidation ISO sodium chromate(VI) results in increased oxidation of TXN2 protein CTD PMID:18328613 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions
increases expression		 ISO ERRFI1 protein inhibits the reaction [sodium chromate(VI) results in increased expression of UCHL1 protein] CTD PMID:28688920 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Uvrag UV radiation resistance associated decreases expression ISO sodium chromate(VI) results in decreased expression of UVRAG mRNA CTD PMID:16283527 NCBI chr 1:153,185,356...153,442,200
Ensembl chr 1:153,185,395...153,442,136 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      chemical role 19420
        oxidising agent 11997
          sodium chromate 43
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      chalcogen 19513
                        oxygen atom 19488
                          oxygen molecular entity 19488
                            oxide 12745
                              oxoanion 10291
                                transition element oxoanion 5588
                                  chromium oxoanion 5571
                                    chromate(2-) 2860
                                      sodium chromate 43
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