Gene: Setdb1 (SET domain, bifurcated 1) Rattus norvegicus
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Symbol: Setdb1
Name: SET domain, bifurcated 1
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); promoter-specific chromatin binding (ortholog); INVOLVED IN response to ethanol; response to vitamin; bone development (ortholog); PARTICIPATES IN homocysteine metabolic pathway; methionine cycle/metabolic pathway; Wnt signaling, non-canonical pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); Autistic Disorder (ortholog); autistic disorder (ortholog); FOUND IN cytosol (ortholog); intracellular membrane-bounded organelle (ortholog); nuclear chromatin (ortholog); INTERACTS WITH bisphenol A; glyphosate; T-2 Toxin
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: histone-lysine N-methyltransferase SETDB1; LOC310668; LOC689883; similar to Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET)
Orthologs:
Homo sapiens (human) : SETDB1 (SET domain bifurcated 1)  HGNC
Mus musculus (house mouse) : Setdb1 (SET domain, bifurcated 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Setdb1 (SET domain bifurcated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SETDB1 (SET domain bifurcated 1)
Canis lupus familiaris (dog) : SETDB1 (SET domain bifurcated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Setdb1 (SET domain bifurcated 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02196,495,867 - 196,527,412 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02215,994,295 - 216,025,842 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42190,232,228 - 190,264,309 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12190,195,015 - 190,227,043 (-)NCBI
Celera2175,432,236 - 175,463,195 (-)NCBI
Cytogenetic Map2q34NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Setdb1
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 1308370
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-05-30
Status: ACTIVE