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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:colorimetric reagent
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Accession:CHEBI:67126 term browser browse the term
Definition:A reagent used in the determination of the concentration of a coloured chemical element or chemical compound in solution.
Synonyms:related_synonym: color reagent;   color reagents;   colorimetric reagents;   colour reagent;   colour reagents


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3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO thiazolyl blue results in decreased activity of ABCB1 protein CTD PMID:15451006 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Aco2 aconitase 2 multiple interactions ISO [Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Potassium deficiency results in decreased activity of ACO2 protein] which results in decreased reduction of thiazolyl blue CTD PMID:12548706 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Casp3 caspase 3 increases activity ISO thiazolyl blue results in increased activity of CASP3 protein CTD PMID:22401948 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases activity ISO thiazolyl blue results in increased activity of CASP8 protein CTD PMID:22401948 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 increases reduction
multiple interactions		 ISO NQO2 protein results in increased reduction of thiazolyl blue
resveratrol inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]		 CTD PMID:29281794 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
antimony trichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6 activating transcription factor 6 multiple interactions
increases expression		 ISO [Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of ATF6 mRNA
antimony trichloride results in increased expression of ATF6 mRNA		 CTD PMID:34091186 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
decreases expression		 ISO [Arsenic Trioxide co-treated with antimony trichloride] results in decreased expression of ATP2A2 mRNA; Arsenic Trioxide promotes the reaction [antimony trichloride results in decreased expression of ATP2A2 protein]
antimony trichloride results in decreased expression of ATP2A2 mRNA; antimony trichloride results in decreased expression of ATP2A2 protein		 CTD PMID:34091186 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma multiple interactions ISO [Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of CAMK2G mRNA CTD PMID:34091186 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050 		JBrowse link
G Casp12 caspase 12 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of CASP12 mRNA
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of CASP12 mRNA		 CTD PMID:34091186 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression		 ISO antimony trichloride results in increased cleavage of CASP3 protein
arsenic trichloride promotes the reaction [antimony trichloride results in increased cleavage of CASP3 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of CASP3 mRNA]		 CTD PMID:30055241 PMID:34091186 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 decreases expression ISO antimony trichloride results in decreased expression of DDB1 mRNA; antimony trichloride results in decreased expression of DDB1 protein CTD PMID:20509621 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of DDIT3 mRNA; antimony trichloride results in increased expression of DDIT3 protein
antimony trichloride promotes the reaction [arsenic trichloride results in increased expression of DDIT3 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of DDIT3 mRNA]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of DDIT3 protein]		 CTD PMID:34091186 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 multiple interactions
increases expression		 ISO [Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of ERN2 mRNA
antimony trichloride results in increased expression of ERN2 mRNA		 CTD PMID:34091186 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of HSPA5 mRNA; antimony trichloride results in increased expression of HSPA5 protein
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of HSPA5 protein; antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 mRNA]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of HSPA5 mRNA]		 CTD PMID:34091186 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of ITPR2 mRNA
antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of ITPR2 mRNA]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of ITPR2 mRNA]		 CTD PMID:34091186 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions		 ISO antimony trichloride results in increased phosphorylation of MAPK1 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK1 protein]		 CTD PMID:30055241 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO antimony trichloride results in increased phosphorylation of MAPK3 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK3 protein]		 CTD PMID:30055241 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of MAPK8 protein
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of MAPK8 mRNA; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of MAPK8 protein]		 CTD PMID:34091186 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Ryr2 ryanodine receptor 2 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of RYR2 mRNA; antimony trichloride results in increased expression of RYR2 protein
[Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of RYR2 mRNA; antimony trichloride promotes the reaction [Arsenic Trioxide results in decreased expression of RYR2 protein]; Arsenic Trioxide promotes the reaction [antimony trichloride results in decreased expression of RYR2 protein]		 CTD PMID:34091186 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions		 ISO antimony trichloride results in decreased expression of SIRT1 mRNA; antimony trichloride results in decreased expression of SIRT1 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Cycloheximide promotes the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Dactinomycin affects the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; U 0126 inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]		 CTD PMID:30055241 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions		 ISO antimony trichloride results in increased expression of TRP53 mRNA; antimony trichloride results in increased expression of TRP53 protein
antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of TRP53 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of TRP53 mRNA]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of TRP53 protein]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of TRP53 protein]		 CTD PMID:34091186 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions
increases expression		 ISO [arsenic trichloride co-treated with antimony trichloride] results in increased expression of XBP1 mRNA; antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of XBP1 protein]; arsenic trichloride inhibits the reaction [antimony trichloride results in increased expression of XBP1 protein]
antimony trichloride results in increased expression of XBP1 mRNA; antimony trichloride results in increased expression of XBP1 protein		 CTD PMID:34091186 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions
affects binding		 ISO antimony trichloride inhibits the reaction [XPA protein binds to Zinc]
antimony trichloride binds to XPA protein		 CTD PMID:20509621 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726 		JBrowse link
Term paths to the root
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  CHEBI ontology 19841
    role 19817
      application 19661
        reagent 18015
          colorimetric reagent 22
            1,2-naphthoquinone-4-sulfonic acid 0
            3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide 5
            alizarin complexone 0
            antimony trichloride 18
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