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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:butachlor
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Accession:CHEBI:3230 term browser browse the term
Definition:An aromatic amide that is 2-choro-N-(2,6-diethylphenyl)acetamide in which the amide nitrogen has been replaced by a butoxymethyl group.
Synonyms:exact_synonym: N-(butoxymethyl)-2-chloro-N-(2,6-diethylphenyl)acetamide
 related_synonym: 2',6'-Diethyl-N-butoxymethyl-2-chloroacetanilide;   2',6'-Diethyl-N-butoxymethyl-alpha-chloroacetanilide;   2-Chloro-2',6'-diethyl-N-(butoxymethyl)acetanilide;   Formula=C17H26ClNO2;   InChI=1S/C17H26ClNO2/c1-4-7-11-21-13-19(16(20)12-18)17-14(5-2)9-8-10-15(17)6-3/h8-10H,4-7,11-13H2,1-3H3;   InChIKey=HKPHPIREJKHECO-UHFFFAOYSA-N;   N-(Butoxymethyl)-2-chloro-2',6'-diethylacetanilide;   N-Butoxymethyl-alpha-chloro-2',6'-diethylacetanilide;   SMILES=C1=CC=C(C(=C1CC)N(COCCCC)C(CCl)=O)CC
 xref: AGR:IND601190844;   CAS:23184-66-9;   KEGG:C10931
 xref_mesh: MESH:C054409
 xref: MetaCyc:CPD-18941;   PMID:20183093;   PMID:25097380;   PMID:25378033;   PMID:25528421;   PMID:25708297;   PMID:25763539;   PMID:26027538;   PMID:26368393;   PMID:26372161;   PMID:26461443;   PMID:26946506;   PMID:26971167;   PMID:27071456;   PMID:27182978;   PMID:27419617;   PMID:27480594;   PMID:27514993;   PMID:27522569;   PMID:27579872;   PMID:27943158;   PMID:27974272;   PMID:27987462;   PMID:28045224;   PMID:28190210;   PPDB:101;   Reaxys:2873811


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butachlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin increases expression ISO butachlor results in increased expression of ALB protein CTD PMID:34351278 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO butachlor results in decreased expression of APAF1 mRNA CTD PMID:34351278 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Ar androgen receptor increases activity ISO butachlor results in increased activity of AR protein CTD PMID:20143881 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atg5 autophagy related 5 decreases expression
increases expression		 ISO butachlor results in decreased expression of ATG5 mRNA
butachlor results in increased expression of ATG5 protein		 CTD PMID:34351278 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Casp3 caspase 3 decreases expression ISO butachlor results in decreased expression of CASP3 mRNA CTD PMID:34351278 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 decreases expression ISO butachlor results in decreased expression of CASP9 mRNA CTD PMID:34351278 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cycs cytochrome c, somatic decreases expression ISO butachlor results in decreased expression of CYCS mRNA CTD PMID:34351278 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of butachlor CTD PMID:11133395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of butachlor CTD PMID:11133395 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO butachlor results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Il10 interleukin 10 decreases expression ISO butachlor results in decreased expression of IL10 mRNA CTD PMID:34351278 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO butachlor results in increased expression of MAP1LC3B protein CTD PMID:34351278 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO butachlor results in decreased expression of MTOR mRNA CTD PMID:34351278 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases activity ISO butachlor results in increased activity of NR1H4 protein CTD PMID:20143881 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases activity ISO butachlor results in increased activity of NR3C1 protein CTD PMID:20143881 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO butachlor results in decreased expression of SQSTM1 mRNA; butachlor results in decreased expression of SQSTM1 protein CTD PMID:34351278 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO butachlor binds to THRB protein CTD PMID:28973306 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tnf tumor necrosis factor decreases expression ISO butachlor results in decreased expression of TNF mRNA CTD PMID:34351278 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        xenobiotic 18707
          butachlor 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            inorganic hydride 18093
                              pnictogen hydride 18082
                                nitrogen hydride 17989
                                  azane 17798
                                    ammonia 17797
                                      organic amino compound 17797
                                        primary amino compound 9301
                                          primary amine 6318
                                            primary arylamine 3644
                                              aniline 3482
                                                anilide 1104
                                                  N-phenylacetamide 235
                                                    butachlor 18
paths to the root