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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:undecan-2-one
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Accession:CHEBI:17700 term browser browse the term
Definition:A dialkyl ketone with methyl and nonyl as the two alkyl groups.
Synonyms:related_synonym: 2-Undecanone;   2-hendecanone;   Formula=C11H22O;   InChI=1S/C11H22O/c1-3-4-5-6-7-8-9-10-11(2)12/h3-10H2,1-2H3;   InChIKey=KYWIYKKSMDLRDC-UHFFFAOYSA-N;   Methyl nonyl ketone;   SMILES=CCCCCCCCCC(C)=O;   rue ketone
 alt_id: CHEBI:11658;   CHEBI:1280;   CHEBI:19792
 xref: CAS:112-12-9;   DrugBank:DB08688;   HMDB:HMDB0033713;   KEGG:C01875;   KNApSAcK:C00030758;   LIPID_MAPS_instance:LMFA12000002
 xref_mesh: MESH:C526928
 xref: MetaCyc:2-UNDECANONE;   PDBeChem:UOC;   PMID:17453350;   PMID:20931852;   PMID:21366058;   PMID:21738794;   PMID:23292923;   PPDB:1397;   Reaxys:1749573;   Wikipedia:2-Undecanone


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undecan-2-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO undecan-2-one binds to and results in decreased activity of AR protein CTD PMID:27633901 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO undecan-2-one binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO
EXP		 undecan-2-one results in increased expression of HMOX1 protein
undecan-2-one promotes the reaction [NFE2L2 promotes the reaction [Particulate Matter results in increased expression of HMOX1 protein]]		 CTD PMID:35285579 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO undecan-2-one inhibits the reaction [Particulate Matter results in increased expression of IL18 protein] CTD PMID:35285579 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP		 undecan-2-one inhibits the reaction [Particulate Matter results in increased expression of IL1B protein] CTD PMID:35285579 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP		 undecan-2-one inhibits the reaction [Particulate Matter results in increased expression of IL6 protein] CTD PMID:35285579 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP
ISO		 [Particulate Matter co-treated with undecan-2-one] results in increased expression of NFE2L2 protein; undecan-2-one inhibits the reaction [Particulate Matter results in decreased expression of NFE2L2 protein]; undecan-2-one promotes the reaction [NFE2L2 promotes the reaction [Particulate Matter results in increased expression of HMOX1 protein]]
undecan-2-one results in increased expression of and affects the localization of NFE2L2 protein		 CTD PMID:35285579 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO
EXP		 undecan-2-one inhibits the reaction [Particulate Matter results in increased phosphorylation of NFKBIA protein] CTD PMID:35285579 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO undecan-2-one binds to and results in decreased activity of NR3C1 protein CTD PMID:27633901 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP		 undecan-2-one inhibits the reaction [Particulate Matter results in increased expression of RELA protein modified form]; undecan-2-one inhibits the reaction [Particulate Matter results in increased expression of RELA protein] CTD PMID:35285579 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 undecan-2-one inhibits the reaction [Particulate Matter results in increased expression of TNF protein] CTD PMID:35285579 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        pesticide 17897
          rodenticide 9546
            undecan-2-one 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbonyl compound 18869
                                    ketone 17165
                                      dialkyl ketone 51
                                        undecan-2-one 11
paths to the root