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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:17700
Term: undecan-2-one
Definition: A dialkyl ketone with methyl and nonyl as the two alkyl groups.
Chemical ID: MESH:C526928
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2multiple interactionsEXP 6480464CTD[Particulate Matter co-treated with undecan-2-one] results in increased expression of NFE2L2 protein; undecan-2-one inhibits the reaction [Particulate Matter results in decreased expression of NFE2L2 protein]; undecan-2-one promotes the reaction [NFE2L2 promotes the reaction [Particulate Matter results in increased expression of HMOX1 protein]]PMID:35285579
Nfe2l2multiple interactionsISONfe2l2 (Mus musculus)6480464CTDundecan-2-one results in increased expression of and affects the localization of NFE2L2 proteinPMID:35285579
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