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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:altered insulin signaling pathway
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Accession:PW:0000596 term browser browse the term
Definition:An insulin signaling pathway that deviates from what its normal course should be. Deregulation of insulin signaling can have profound health consequences due to its potential to alter glucose and energy homeostasis.
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altered insulin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 ISO RGD PMID:9809695 RGD:2313694 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Insr insulin receptor ISO RGD PMID:9809695 RGD:2313694 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3864
      homeostasis pathway 1772
        energy homeostasis pathway 431
          insulin signaling pathway 159
            altered insulin signaling pathway 2
Path 2
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3864
      homeostasis pathway 1772
        organic chemical homeostasis pathway 767
          glucose homeostasis pathway 344
            insulin signaling pathway 159
              altered insulin signaling pathway 2
paths to the root