| 155260360 | COP/HsdUwmRrrc | Copenhagen | Donated from Michael Gould/Jim Shull at University of Wisconsin Madison to Rat Resource & Research Center, | Rat Resource and Research Center, RGD HRDP, contact HRDP | inbred | 1 | name |
| 1579712 | FHH-Klf6m1Mcwi | | Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. V135G mutation is generated. | | mutant | 1 | old_strain_symbol |
| 1331815 | LEW/Mol | LEW/Mol | This substrain can be traced originally to Scripps Clinic, La Jolla, to University of Pennsylvania to Simonsen Laboratories in 1966, to Institute of Pathological Anatomy, University of Copenhagen, Denmark 1973. From University of Cope openhagen to M&B A/S (Mollegaard Breeding Center Ltd., Denmark ) from 1977 to 2002. (now Taconic Europe) | | inbred | 4 | origin |
| 1566443 | LEW/MolTac | Lewis | Scripps Clinic, La Jolla, California to the University of Pennsylvania; to Simonsen Laboratories in 1966 at F20; to the Institute of Pathological Anatomy, University of Copenhagen, Denmark in 1973 at F28. The Lewis rat was obtained from the University of Cope tyle='font-weight:700;'>Copenhagen by M&B in 1977, and was received at Taconic, USA in 2002, where it was rederived. | Taconic | inbred | 1 | origin |
| 1358153 | COP/CrCrl | | Inbred strain is from Curtis in 1921 at Columbia University Institute for Cancer Research. To National Cancer Institute Animal Production Program (Cr). To Charles River from the National Cancer Institute in 1998. | Charles River Laboratories | inbred | 14 | old_strain_name |
| 60998 | COP | | This Copenhagen (COP) rat was an inbred strain from Curtiss 1921 at Columbia University Institute for Cancer Research. | | inbred | 4 | old_strain_name , origin |
| 1302643 | ACI/NKyo | august copenhagen irish | NIH (1988, F143) > Kyo (F43) | National BioResource Project for the Rat in Japan | inbred | 1 | name |
| 405878045 | ACI | August x Copenhagen Irish | Curtiss and Dunning 1926 at the Columbia University Institute for Cancer Research, after accidental mating between an August male with an Irish coat and a COP (Copenhagen2331)female. This is the parent to ACI substrains sent to Heston 1945 at F30, to National In stitutes of Health 1950 at F41. Subsequent sublines from Dunning or NIH. | | inbred | 1 | origin , name |
| 1547869 | ACI/Eur | August x Copenhagen Irish | Curtiss and Dunning 1926 at the Columbia University Institute for Cancer Research. To Heston 1945 at F30, to National Institutes of Health 1950 at F41. Subsequent sublines from Dunning or NIH | | inbred | 5 | name |
| 7364991 | ACI/EurMcwi | ACI (August × Copenhagen Irish) | substrain of ACI derived from ACI/Eur | RGD HRDP, contact Hybrid Rat Diversity Program at
HRDP@mcw.edu | inbred | 1 | name |
| 629006528 | ACI/EurMcwiRrrc | ACI (August × Copenhagen Irish) | substrain of ACI derived from ACI/EurMcwi donated to RRRC by Howard Jacob from Medical College of Wisconsin. | Rat Resource & Research Center | inbred | 1 | name |
| 70453 | SR | | Rapp from a Sprague-Dawley outbred colony developed by LK Dahl, Brookhaven National Laboratories, Upton, New York, selected for resistance to salt-induced hypertension (Dahl et al 1962a,b). Also designated R/JR by Rapp (1984), and Dahl R by Mollegard, Copenhag en. | | inbred | 1 | origin |
| 69369 | SS | | From a colony of Sprague-Dawley outbred rats developed by LK Dahl, Brookhaven National Laboratories, Upton, New York, selected for sensitivity to salt-induced hypertension (Dahl et al 1962a,b, Rapp 1982). Also designated S/JR by Rapp (1984), who gives an extensive review of the characteristics of th e strain, and Dahl S by Mollegard, Copenhagen. Note that the Dahl selected strain has been independently inbred at the NIH, and designated DSS/N. There is likely to be confusion among these colonies unless considerable care is taken with nomenclature. Stlezin et al (1992) found that SS and SR had about 80% of DNA fingerprint bands in common, compared with 50% between SHR and WKY. According to Ginn et al, (1993) analysis of RFLPs and microsatellites suggest that SR is a reasonably good control strain for SS, though crosses between SS and unrelated normotensive strains will be useful in identifying the loci responsible for salt-induced hypertension. | | inbred | 3 | origin |