Folh1b (Putative N-acetylated-alpha-linked acidic dipeptidase) - Rat Genome Database

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Gene: Folh1b (Putative N-acetylated-alpha-linked acidic dipeptidase) Chinchilla lanigera
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Symbol: Folh1b (Ensembl: FOLH1)
Name: Putative N-acetylated-alpha-linked acidic dipeptidase (Ensembl:folate hydrolase 1)
RGD ID: 8864604
Description: ENCODES a protein that exhibits metallocarboxypeptidase activity (ortholog); INVOLVED IN C-terminal protein deglutamylation (ortholog); ASSOCIATED WITH intellectual disability (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: folate hydrolase 1B
RGD Orthologs
Human
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554143,870,873 - 3,922,620 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554143,874,182 - 3,920,616 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Folh1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554143,870,873 - 3,922,620 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554143,874,182 - 3,920,616 (-)NCBIChiLan1.0ChiLan1.0
FOLH1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381189,659,268 - 89,698,718 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1189,639,237 - 89,698,599 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl1189,659,297 - 89,698,722 (+)EnsemblGRCh38hg38GRCh38
GRCh371189,392,436 - 89,431,886 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361189,032,113 - 89,071,534 (+)NCBINCBI36Build 36hg18NCBI36
Celera1185,199,516 - 85,237,920 (-)NCBICelera
Cytogenetic Map11q14.3NCBI
HuRef1185,629,642 - 85,669,027 (+)NCBIHuRef
CHM1_11189,275,369 - 89,314,766 (+)NCBICHM1_1
T2T-CHM13v2.01189,578,945 - 89,618,403 (+)NCBIT2T-CHM13v2.0
LOC101964348
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494775,262,299 - 75,419,205 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493673632,706 - 79,902 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493673632,617 - 79,968 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOLH1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1180,800,069 - 80,868,176 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl180,802,676 - 80,869,782 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604344,874,371 - 44,939,977 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Folh1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624845441,511 - 502,545 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624845444,756 - 502,577 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000021507   ⟹   ENSCLAP00000021305
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554143,870,873 - 3,922,620 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000021508   ⟹   ENSCLAP00000021306
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554143,874,250 - 3,920,614 (-)Ensembl
RefSeq Acc Id: XM_013512091   ⟹   XP_013367545
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554143,874,182 - 3,920,616 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013367545 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000021305
  ENSCLAP00000021305.1
  ENSCLAP00000021306.1
RefSeq Acc Id: XP_013367545   ⟸   XM_013512091
- UniProtKB: A0A8C2YT36 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000021305   ⟸   ENSCLAT00000021507
Ensembl Acc Id: ENSCLAP00000021306   ⟸   ENSCLAT00000021508
Protein Domains
PA   Peptidase M28   Transferrin receptor-like dimerisation


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014594 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000021507 ENTREZGENE
  ENSCLAT00000021507.1 UniProtKB/TrEMBL
  ENSCLAT00000021508.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.930.40 UniProtKB/TrEMBL
  3.50.30.30 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro PA_dom_sf UniProtKB/TrEMBL
  PA_domain UniProtKB/TrEMBL
  Peptidase_M28 UniProtKB/TrEMBL
  Peptidase_M28B UniProtKB/TrEMBL
  TFR-like_dimer_dom UniProtKB/TrEMBL
  TFR-like_dimer_dom_sf UniProtKB/TrEMBL
NCBI Gene Folh1b ENTREZGENE
PANTHER GLUTAMATE CARBOXYPEPTIDASE 2 UniProtKB/TrEMBL
  PTHR10404 UniProtKB/TrEMBL
Pfam Peptidase_M28 UniProtKB/TrEMBL
  PF02225 UniProtKB/TrEMBL
  TFR_dimer UniProtKB/TrEMBL
Superfamily-SCOP PA domain UniProtKB/TrEMBL
  SSF47672 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A8C2YT36 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YT37_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-09 Folh1b  Putative N-acetylated-alpha-linked acidic dipeptidase  Folh1b  folate hydrolase 1B  Symbol and/or name change 5135510 APPROVED