Lama5 (laminin subunit alpha 5) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Lama5 (laminin subunit alpha 5) Chinchilla lanigera
Analyze
Symbol: Lama5
Name: laminin subunit alpha 5
RGD ID: 8831957
Description: ENCODES a protein that exhibits cell adhesion mediator activity (ortholog); integrin binding (ortholog); receptor ligand activity (ortholog); INVOLVED IN animal organ morphogenesis (ortholog); branching involved in salivary gland morphogenesis (ortholog); branching involved in ureteric bud morphogenesis (ortholog); PARTICIPATES IN syndecan signaling pathway; ASSOCIATED WITH benign familial hematuria (ortholog); bent bone dysplasia syndrome 1 (ortholog); bent bone dysplasia syndrome 2 (ortholog); FOUND IN basement membrane (ortholog); extracellular matrix (ortholog); extracellular matrix of synaptic cleft (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: laminin subunit alpha-5; laminin, alpha 5
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555281,713,125 - 1,753,116 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555281,713,110 - 1,753,374 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Lama5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555281,713,125 - 1,753,116 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555281,713,110 - 1,753,374 (+)NCBIChiLan1.0ChiLan1.0
LAMA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382062,309,065 - 62,367,312 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2062,307,955 - 62,367,312 (-)EnsemblGRCh38hg38GRCh38
GRCh372060,884,121 - 60,942,368 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362060,317,516 - 60,375,763 (-)NCBINCBI36Build 36hg18NCBI36
Build 342060,317,515 - 60,375,763NCBI
Celera2057,619,270 - 57,677,579 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2057,659,916 - 57,715,071 (-)NCBIHuRef
CHM1_12060,784,876 - 60,843,394 (-)NCBICHM1_1
T2T-CHM13v2.02064,100,010 - 64,163,029 (-)NCBIT2T-CHM13v2.0
Lama5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392179,818,166 - 179,867,652 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2179,818,166 - 179,867,652 (-)EnsemblGRCm39 Ensembl
GRCm382180,176,373 - 180,225,904 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2180,176,373 - 180,225,859 (-)EnsemblGRCm38mm10GRCm38
MGSCv372179,911,078 - 179,960,564 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362180,105,781 - 180,155,267 (-)NCBIMGSCv36mm8
Celera2184,258,583 - 184,308,017 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2102.7NCBI
Lama5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83187,647,904 - 187,695,974 (-)NCBIGRCr8
mRatBN7.23167,270,296 - 167,318,370 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3167,270,296 - 167,318,451 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3171,647,270 - 171,694,902 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03180,606,358 - 180,653,991 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03177,271,257 - 177,319,327 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03175,553,042 - 175,601,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3175,553,045 - 175,601,127 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03181,517,512 - 181,565,641 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43169,233,897 - 169,282,410 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13169,144,153 - 169,145,258 (-)NCBI
Celera3165,261,840 - 165,309,879 (+)NCBICelera
Cytogenetic Map3q43NCBI
LAMA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22168,089,341 - 68,151,288 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12068,082,714 - 68,144,409 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02058,673,850 - 58,677,760 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12059,991,859 - 60,052,486 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2059,992,130 - 60,055,765 (-)Ensemblpanpan1.1panPan2
LAMA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12446,315,008 - 46,351,279 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2445,552,009 - 45,597,798 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02447,171,634 - 47,217,418 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12446,272,834 - 46,318,659 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02446,396,082 - 46,441,995 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,150,451 - 47,196,224 (-)NCBIUU_Cfam_GSD_1.0
Lama5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640194,474,591 - 194,519,778 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365149,928,316 - 9,973,349 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365149,928,234 - 9,973,425 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1761,697,517 - 61,747,955 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11761,698,370 - 61,747,795 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LAMA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121,872,740 - 1,930,037 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21,872,832 - 1,929,854 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605049,816,885 - 49,868,098 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lama5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474128,157,172 - 28,217,113 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474128,156,956 - 28,217,133 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000013530   ⟹   ENSCLAP00000013378
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555281,713,125 - 1,753,116 (+)Ensembl
RefSeq Acc Id: XM_013507490   ⟹   XP_013362944
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555281,713,110 - 1,753,374 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507491   ⟹   XP_013362945
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555281,713,110 - 1,753,374 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507492   ⟹   XP_013362946
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555281,713,110 - 1,753,374 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013362944 (Get FASTA)   NCBI Sequence Viewer  
  XP_013362945 (Get FASTA)   NCBI Sequence Viewer  
  XP_013362946 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000013378
  ENSCLAP00000013378.1
RefSeq Acc Id: XP_013362944   ⟸   XM_013507490
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VC53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013362945   ⟸   XM_013507491
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VC53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013362946   ⟸   XM_013507492
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VC53 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000013378   ⟸   ENSCLAT00000013530

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009241 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013530 ENTREZGENE
  ENSCLAT00000013530.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  Laminin/Netrin_ECM UniProtKB/TrEMBL
  Laminin_aI UniProtKB/TrEMBL
  Laminin_dom_II UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
  Laminin_IV UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
  LE_dom UniProtKB/TrEMBL
  Znf_SWIM UniProtKB/TrEMBL
NCBI Gene Lama5 ENTREZGENE
PANTHER NETRIN-A-RELATED UniProtKB/TrEMBL
  NETRIN/LAMININ-RELATED UniProtKB/TrEMBL
Pfam Laminin_B UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/TrEMBL
  Laminin_I UniProtKB/TrEMBL
  Laminin_II UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
PRINTS EGFLAMININ UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
  LAMININ_IVA UniProtKB/TrEMBL
  LAMININ_NTER UniProtKB/TrEMBL
  ZF_SWIM UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  LamB UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  LamNT UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A8C2VC53 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Lama5  laminin subunit alpha 5    laminin, alpha 5  Symbol and/or name change 5135510 APPROVED