Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Stk10 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | STK10 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of STK10 mRNA | CTD | PMID:22079256 | Stk10 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Stk10 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of STK10 mRNA | CTD | PMID:36331819 | Stk10 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Stk10 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of STK10 mRNA | CTD | PMID:22206623 | Stk10 | Rat | 1-benzylpiperazine | increases expression | EXP | | 6480464 | N-benzylpiperazine results in increased expression of STK10 mRNA | CTD | PMID:26821219 | Stk10 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of STK10 mRNA | CTD | PMID:25380136 | Stk10 | Rat | 17beta-estradiol | multiple interactions | ISO | STK10 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of STK10 mRNA | CTD | PMID:30165855 | Stk10 | Rat | 17beta-estradiol | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Estradiol results in increased expression of STK10 mRNA | CTD | PMID:31614463 | Stk10 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of STK10 mRNA | CTD | PMID:32741896 | Stk10 | Rat | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of STK10 mRNA | CTD | PMID:32741896 | Stk10 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Stk10 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Stk10 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of STK10 mRNA | CTD | PMID:21346803 | Stk10 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of STK10 mRNA | CTD | PMID:21346803 | Stk10 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of STK10 mRNA | CTD | PMID:30851411 | Stk10 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Stk10 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of STK10 mRNA | CTD | PMID:26251327 | Stk10 | Rat | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of STK10 mRNA | CTD | PMID:25380136 | Stk10 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Stk10 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of STK10 mRNA | CTD | PMID:18648102 | Stk10 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | STK10 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of STK10 gene | CTD | PMID:31601247 | Stk10 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of STK10 mRNA | CTD | PMID:31881176 | Stk10 | Rat | acetylsalicylic acid | affects response to substance | ISO | STK10 (Homo sapiens) | 6480464 | STK10 polymorphism affects the susceptibility to Aspirin | CTD | PMID:21905501 | Stk10 | Rat | all-trans-retinoic acid | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of STK10 mRNA | CTD | PMID:16140955 | Stk10 | Rat | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of STK10 mRNA | CTD | PMID:20488242 | Stk10 | Rat | all-trans-retinoic acid | multiple interactions | ISO | STK10 (Homo sapiens) | 6480464 | Thiophenes analog promotes the reaction [Tretinoin results in increased expression of STK10 mRNA] | CTD | PMID:16140955 | Stk10 | Rat | alpha-Zearalanol | increases expression | EXP | | 6480464 | Zeranol results in increased expression of STK10 mRNA | CTD | PMID:35163327 | Stk10 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of STK10 mRNA | CTD | PMID:16483693 | Stk10 | Rat | antirheumatic drug | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of STK10 mRNA | CTD | PMID:24449571 | Stk10 | Rat | aristolochic acid A | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of STK10 mRNA | CTD | PMID:33212167 | Stk10 | Rat | arsenite(3-) | multiple interactions | ISO | STK10 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to STK10 mRNA] | CTD | PMID:32406909 | Stk10 | Rat | azoxystrobin | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | azoxystrobin results in decreased expression of STK10 mRNA | CTD | PMID:33512557 | Stk10 | Rat | benzo[a]pyrene | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of STK10 mRNA | CTD | PMID:20064835 | Stk10 | Rat | benzo[a]pyrene | affects methylation | ISO | STK10 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of STK10 intron | CTD | PMID:30157460 | Stk10 | Rat | benzo[a]pyrene | decreases expression | ISO | Stk10 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of STK10 mRNA | CTD | PMID:21569818 | Stk10 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Stk10 | Rat | benzo[e]pyrene | increases methylation | ISO | STK10 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of STK10 intron | CTD | PMID:30157460 | Stk10 | Rat | bisphenol A | decreases expression | ISO | Stk10 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of STK10 mRNA | CTD | PMID:22687993 | Stk10 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of STK10 mRNA | CTD | PMID:34947998 | Stk10 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of STK10 mRNA | CTD | PMID:25181051 | Stk10 | Rat | Bisphenol B | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of STK10 protein | CTD | PMID:34186270 | Stk10 | Rat | bisphenol F | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of STK10 protein | CTD | PMID:34186270 | Stk10 | Rat | buta-1,3-diene | decreases expression | ISO | Stk10 (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of STK10 mRNA | CTD | PMID:29038090 | Stk10 | Rat | caffeine | decreases phosphorylation | ISO | STK10 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of STK10 protein | CTD | PMID:35688186 | Stk10 | Rat | carbon nanotube | multiple interactions | ISO | STK10 (Homo sapiens) | 6480464 | [Nanotubes and Carbon co-treated with calfactant] results in decreased expression of STK10 protein | CTD | PMID:23026733 | Stk10 | Rat | carbon nanotube | decreases expression | ISO | Stk10 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Stk10 | Rat | CGP 52608 | multiple interactions | ISO | STK10 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to STK10 gene] | CTD | PMID:28238834 | Stk10 | Rat | chlorpyrifos | decreases expression | ISO | Stk10 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of STK10 mRNA | CTD | PMID:37019170 | Stk10 | Rat | choline | multiple interactions | ISO | Stk10 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of STK10 gene | CTD | PMID:20938992 | Stk10 | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of STK10 mRNA | CTD | PMID:24386269 | Stk10 | Rat | coumarin | affects phosphorylation | ISO | STK10 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of STK10 protein | CTD | PMID:35688186 | Stk10 | Rat | cyclosporin A | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of STK10 mRNA | CTD | PMID:20106945 | Stk10 | Rat | dibutyl phthalate | decreases expression | ISO | Stk10 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of STK10 mRNA | CTD | PMID:21266533 | Stk10 | Rat | disodium selenite | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of STK10 mRNA | CTD | PMID:18175754 | Stk10 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of STK10 mRNA | CTD | PMID:29391264 | Stk10 | Rat | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of STK10 mRNA | CTD | PMID:17920746 | Stk10 | Rat | ethanol | increases expression | ISO | Stk10 (Mus musculus) | 6480464 | Ethanol results in increased expression of STK10 mRNA | CTD | PMID:30319688 | Stk10 | Rat | ethyl methanesulfonate | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of STK10 mRNA | CTD | PMID:23649840 | Stk10 | Rat | folic acid | multiple interactions | ISO | Stk10 (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | Stk10 | Rat | folic acid | decreases expression | ISO | Stk10 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of STK10 mRNA | CTD | PMID:25629700 | Stk10 | Rat | FR900359 | decreases phosphorylation | ISO | STK10 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of STK10 protein | CTD | PMID:37730182 | Stk10 | Rat | fulvestrant | multiple interactions | ISO | STK10 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of STK10 gene | CTD | PMID:31601247 | Stk10 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of STK10 mRNA | CTD | PMID:22061828 | Stk10 | Rat | ivermectin | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of STK10 protein | CTD | PMID:32959892 | Stk10 | Rat | L-methionine | multiple interactions | ISO | Stk10 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of STK10 gene | CTD | PMID:20938992 | Stk10 | Rat | lead diacetate | increases expression | ISO | Stk10 (Mus musculus) | 6480464 | lead acetate results in increased expression of STK10 mRNA | CTD | PMID:25270620 | Stk10 | Rat | methapyrilene | increases methylation | ISO | STK10 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of STK10 intron | CTD | PMID:30157460 | Stk10 | Rat | methotrexate | affects expression | ISO | Stk10 (Mus musculus) | 6480464 | Methotrexate affects the expression of STK10 mRNA | CTD | PMID:18502557 | Stk10 | Rat | methoxyacetic acid | affects expression | EXP | | 6480464 | methoxyacetic acid affects the expression of STK10 mRNA | CTD | PMID:20864626 | Stk10 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of STK10 gene | CTD | PMID:35440735 | Stk10 | Rat | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | N more ... | CTD | PMID:12756304 | Stk10 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of STK10 gene | CTD | PMID:33148267 | Stk10 | Rat | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of STK10 mRNA | CTD | PMID:25380136 | Stk10 | Rat | nickel atom | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Nickel results in increased expression of STK10 mRNA | CTD | PMID:25583101 | Stk10 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of STK10 mRNA | CTD | PMID:25729387 | Stk10 | Rat | ozone | multiple interactions | ISO | Stk10 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of STK10 mRNA | CTD | PMID:34911549 | Stk10 | Rat | paracetamol | affects expression | ISO | Stk10 (Mus musculus) | 6480464 | Acetaminophen affects the expression of STK10 mRNA | CTD | PMID:17562736 | Stk10 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of STK10 mRNA | CTD | PMID:33387578 | Stk10 | Rat | paracetamol | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of STK10 mRNA | CTD | PMID:29067470 | Stk10 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Stk10 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of STK10 mRNA | CTD | PMID:36331819 | Stk10 | Rat | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of STK10 mRNA | CTD | PMID:19162173 | Stk10 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of STK10 gene | CTD | PMID:33148267 | Stk10 | Rat | picoxystrobin | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | picoxystrobin results in decreased expression of STK10 mRNA | CTD | PMID:33512557 | Stk10 | Rat | potassium chromate | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of STK10 mRNA | CTD | PMID:22079256 | Stk10 | Rat | potassium chromate | multiple interactions | ISO | STK10 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of STK10 mRNA | CTD | PMID:22079256 | Stk10 | Rat | rac-lactic acid | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of STK10 mRNA | CTD | PMID:30851411 | Stk10 | Rat | rotenone | decreases expression | ISO | STK10 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of STK10 mRNA | CTD | PMID:33512557 | Stk10 | Rat | sodium arsenite | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of STK10 mRNA | CTD | PMID:38568856 | Stk10 | Rat | sodium dodecyl sulfate | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Sodium Dodecyl Sulfate results in increased expression of STK10 mRNA | CTD | PMID:31734321 | Stk10 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of STK10 mRNA | CTD | PMID:19281266 | Stk10 | Rat | sunitinib | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of STK10 mRNA | CTD | PMID:31533062 | Stk10 | Rat | tert-butyl hydroperoxide | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of STK10 mRNA | CTD | PMID:15336504 | Stk10 | Rat | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of STK10 mRNA | CTD | PMID:32741896 | Stk10 | Rat | testosterone enanthate | affects expression | ISO | STK10 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of STK10 mRNA | CTD | PMID:17440010 | Stk10 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of STK10 mRNA | CTD | PMID:34492290 | Stk10 | Rat | thiophenes | multiple interactions | ISO | STK10 (Homo sapiens) | 6480464 | Thiophenes analog promotes the reaction [Tretinoin results in increased expression of STK10 mRNA] | CTD | PMID:16140955 | Stk10 | Rat | thiram | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Thiram results in increased expression of STK10 mRNA | CTD | PMID:38568856 | Stk10 | Rat | titanium dioxide | decreases expression | ISO | Stk10 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of STK10 mRNA | CTD | PMID:27760801 | Stk10 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of STK10 mRNA | CTD | PMID:25729387 | Stk10 | Rat | triphenyl phosphate | affects expression | ISO | STK10 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of STK10 mRNA | CTD | PMID:37042841 | Stk10 | Rat | tungsten | decreases expression | ISO | Stk10 (Mus musculus) | 6480464 | Tungsten results in decreased expression of STK10 mRNA | CTD | PMID:30912803 | Stk10 | Rat | urethane | increases expression | ISO | STK10 (Homo sapiens) | 6480464 | Urethane results in increased expression of STK10 mRNA | CTD | PMID:28818685 | Stk10 | Rat | valproic acid | increases expression | ISO | Stk10 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of STK10 mRNA | CTD | PMID:21427059 | Stk10 | Rat | valproic acid | affects expression | ISO | STK10 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of STK10 mRNA | CTD | PMID:25979313 | |