Tcf25 (TCF25 ribosome quality control complex subunit) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Tcf25 (TCF25 ribosome quality control complex subunit) Heterocephalus glaber
Analyze
Symbol: Tcf25
Name: TCF25 ribosome quality control complex subunit (Ensembl:transcription factor 25)
RGD ID: 18931870
Description: INVOLVED IN regulation of protein K48-linked ubiquitination (ortholog); rescue of stalled cytosolic ribosome (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor 25
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746137,926 - 162,442 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624746137,926 - 162,467 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (ISO)
RQC complex  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tcf25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746137,926 - 162,442 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624746137,926 - 162,467 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
TCF25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381689,873,592 - 89,911,379 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1689,873,566 - 89,913,627 (+)Ensemblhg38GRCh38
GRCh371689,940,000 - 89,977,787 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,467,521 - 88,505,287 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1675,005,365 - 75,042,884 (+)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1675,633,713 - 75,670,835 (+)NCBIHuRef
CHM1_11691,351,261 - 91,389,910 (+)NCBICHM1_1
T2T-CHM13v2.01695,958,631 - 95,997,624 (+)NCBIT2T-CHM13v2.0
Tcf25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398124,097,511 - 124,130,913 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8124,100,492 - 124,130,574 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388123,370,772 - 123,404,174 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,373,753 - 123,403,835 (+)Ensemblmm10GRCm38
MGSCv378125,897,653 - 125,928,073 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368126,259,843 - 126,290,263 (+)NCBIMGSCv36mm8
Celera8127,615,925 - 127,646,697 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map872.1NCBI
Tcf25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,323,789 - 68,358,226 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1968,323,867 - 68,358,240 (+)EnsemblGRCr8
mRatBN7.21951,415,341 - 51,449,725 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,415,543 - 51,449,723 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1958,210,104 - 58,243,915 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,890,618 - 58,921,401 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01961,108,705 - 61,142,516 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1962,123,843 - 62,157,728 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1960,245,135 - 60,275,916 (+)NCBILyon_Normotensive
Lyon_Hypertensive1962,118,625 - 62,149,409 (+)NCBILyon_Hypertensive
F344_StmMcwi1959,855,203 - 59,889,883 (+)NCBIF344_StmMcwi
Rnor_6.01956,178,905 - 56,213,299 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,179,111 - 56,213,310 (+)Ensemblrn6Rnor6.0
Rnor_5.01966,889,815 - 66,924,422 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41953,700,698 - 53,732,930 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1950,650,902 - 50,682,264 (+)NCBICelera
RGSC_v3.11953,705,581 - 53,737,793 (+)NCBI
Cytogenetic Map19q12NCBI
Tcf25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555413,362,666 - 3,387,854 (+)Ensembl
ChiLan1.0NW_0049555413,362,665 - 3,387,506 (+)NCBIChiLan1.0ChiLan1.0
TCF25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21899,726,126 - 99,765,780 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116105,613,583 - 105,652,905 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01670,636,413 - 70,675,841 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11690,302,195 - 90,340,194 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1690,298,175 - 90,340,048 (+)EnsemblpanPan2panpan1.1
TCF25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1563,697,627 - 63,729,780 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl563,681,752 - 63,729,684 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha563,711,734 - 63,742,768 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0563,927,821 - 63,957,965 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl563,924,849 - 63,958,007 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1563,947,036 - 63,978,065 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0563,784,575 - 63,815,793 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,190,933 - 64,221,930 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101977862
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,448,975 - 24,479,415 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641202,624 - 232,962 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936641202,522 - 232,962 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TCF25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6183,451 - 208,903 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16186,068 - 208,841 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26231,361 - 282,700 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TCF25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1575,205,506 - 75,235,290 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl575,205,504 - 75,235,777 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666047186,117 - 220,334 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tcf25
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11742,981,722 - 43,013,219 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000026118   ⟹   ENSHGLP00000025889
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624746137,926 - 162,442 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000026119   ⟹   ENSHGLP00000025890
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624746138,055 - 162,352 (-)Ensembl
RefSeq Acc Id: XM_004842618   ⟹   XP_004842675
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746137,926 - 162,464 (-)NCBI
RefSeq Acc Id: XM_021256516   ⟹   XP_021112175
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746137,926 - 162,466 (-)NCBI
RefSeq Acc Id: XM_021256517   ⟹   XP_021112176
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746137,926 - 162,466 (-)NCBI
RefSeq Acc Id: XM_021256518   ⟹   XP_021112177
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746137,926 - 162,467 (-)NCBI
RefSeq Acc Id: XM_021256519   ⟹   XP_021112178
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746137,931 - 162,465 (-)NCBI
RefSeq Acc Id: XM_021256520   ⟹   XP_021112179
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746140,398 - 162,465 (-)NCBI
RefSeq Acc Id: XP_021112177   ⟸   XM_021256518
- Peptide Label: isoform X4
- UniProtKB: G5APH3 (UniProtKB/TrEMBL),   A0AAX6SWD6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112176   ⟸   XM_021256517
- Peptide Label: isoform X2
- UniProtKB: G5APH3 (UniProtKB/TrEMBL),   A0AAX6SUQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112175   ⟸   XM_021256516
- Peptide Label: isoform X1
- UniProtKB: G5APH3 (UniProtKB/TrEMBL),   A0AAX6SUL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842675   ⟸   XM_004842618
- Peptide Label: isoform X3
- UniProtKB: G5APH3 (UniProtKB/TrEMBL),   A0AAX6P333 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112178   ⟸   XM_021256519
- Peptide Label: isoform X5
- UniProtKB: G5APH3 (UniProtKB/TrEMBL),   A0AAX6SUR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112179   ⟸   XM_021256520
- Peptide Label: isoform X6
- UniProtKB: G5APH3 (UniProtKB/TrEMBL),   A0AAX6STJ5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025889   ⟸   ENSHGLT00000026118
Ensembl Acc Id: ENSHGLP00000025890   ⟸   ENSHGLT00000026119


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018428 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000026118 ENTREZGENE
Gene3D-CATH Tetratricopeptide repeat domain UniProtKB/TrEMBL
InterPro TCF25/Rqc1 UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101697061 UniProtKB/TrEMBL
NCBI Gene Tcf25 ENTREZGENE
PANTHER NULP1-RELATED UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR 25 UniProtKB/TrEMBL
Pfam Tcf25 UniProtKB/TrEMBL
Superfamily-SCOP TPR-like UniProtKB/TrEMBL
UniProt A0AAX6P333 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6STJ5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SUL6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SUQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SUR4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SWD6 ENTREZGENE, UniProtKB/TrEMBL
  G5APH3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-12-11 Tcf25  TCF25 ribosome quality control complex subunit  Tcf25  transcription factor 25  Symbol and/or name change 5135510 APPROVED