Pou3f3 (POU class 3 homeobox 3) - Rat Genome Database

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Gene: Pou3f3 (POU class 3 homeobox 3) Heterocephalus glaber
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Symbol: Pou3f3
Name: POU class 3 homeobox 3
RGD ID: 18916984
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); HMG box domain binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cerebral cortex radially oriented cell migration (ortholog); chemical homeostasis (ortholog); forebrain ventricular zone progenitor cell division (ortholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: POU domain, class 3, transcription factor 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247499,081,906 - 9,087,318 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pou3f3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247499,081,906 - 9,087,318 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
POU3F3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382104,853,276 - 104,927,773 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2104,853,287 - 104,858,574 (+)Ensemblhg38GRCh38
GRCh372105,470,573 - 105,475,032 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362104,838,401 - 104,839,903 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342104,930,486 - 104,931,989NCBI
Celera299,673,184 - 99,674,686 (+)NCBICelera
Cytogenetic Map2q12.1NCBI
HuRef299,242,289 - 99,243,259 (+)NCBIHuRef
CHM1_12105,477,314 - 105,478,580 (+)NCBICHM1_1
T2T-CHM13v2.02105,314,457 - 105,388,956 (+)NCBIT2T-CHM13v2.0
Pou3f3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39142,734,928 - 42,739,370 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl142,734,085 - 42,742,336 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38142,695,768 - 42,700,210 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl142,694,925 - 42,703,176 (+)Ensemblmm10GRCm38
GRCm38.p6 Ensembl142,695,768 - 42,703,176 (+)Ensemblmm10GRCm38
MGSCv37142,753,991 - 42,757,055 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36142,641,692 - 42,643,185 (+)NCBIMGSCv36mm8
MGSCv36143,202,917 - 43,217,049 (+)NCBIMGSCv36mm8
Celera143,024,938 - 43,039,132 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map121.21NCBI
Pou3f3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8952,438,026 - 52,441,152 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl952,435,625 - 52,454,705 (+)EnsemblGRCr8
mRatBN7.2944,945,872 - 44,948,998 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl944,945,872 - 44,948,992 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx953,439,603 - 53,442,731 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0958,562,401 - 58,565,529 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0956,843,728 - 56,846,854 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0949,479,148 - 49,482,246 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl949,479,023 - 49,482,252 (+)Ensemblrn6Rnor6.0
Rnor_5.0949,152,036 - 49,154,632 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4941,873,891 - 41,876,408 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera942,631,024 - 42,668,104 (+)NCBICelera
RGSC_v3.1941,875,036 - 41,877,823 (+)NCBI
Cytogenetic Map9q22NCBI
POU3F3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21222,855,977 - 22,859,194 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A22,858,742 - 22,861,974 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A96,967,943 - 96,972,378 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A105,944,786 - 105,945,424 (+)NCBIPanPan1.1PanPan1.1panPan2
POU3F3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11038,513,872 - 38,517,692 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1038,513,013 - 38,514,684 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1038,438,997 - 38,440,556 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01039,370,326 - 39,371,885 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1039,370,371 - 39,371,870 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11039,093,811 - 39,095,370 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01039,373,547 - 39,375,105 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01039,565,321 - 39,566,880 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
POU3F3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl349,806,161 - 49,807,666 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1349,804,112 - 49,807,730 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2352,014,447 - 52,016,847 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POU3F3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_023666041176,224,323 - 176,228,577 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pou3f3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14118,851,127 - 118,852,611 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004844477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01029152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_004844477   ⟹   XP_004844534
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247499,081,906 - 9,087,318 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004844534 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004844534   ⟸   XM_004844477
- UniProtKB: A0AAX6P5P4 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
  lambda repressor-like DNA-binding domains UniProtKB/TrEMBL
InterPro Homeobox_CS UniProtKB/TrEMBL
  Homeodomain-like_sf UniProtKB/TrEMBL
  IPR001356 UniProtKB/TrEMBL
  Lambda_DNA-bd_dom_sf UniProtKB/TrEMBL
  POU UniProtKB/TrEMBL
  POU_dom UniProtKB/TrEMBL
  POU_domain_TF UniProtKB/TrEMBL
  TF_POU_3 UniProtKB/TrEMBL
KEGG Report hgl:101716926 UniProtKB/TrEMBL
NCBI Gene Pou3f3 ENTREZGENE
PANTHER POU DOMAIN UniProtKB/TrEMBL
  POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 3 UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
  Pou UniProtKB/TrEMBL
PIRSF Transcription_factor_POU UniProtKB/TrEMBL
PRINTS POUDOMAIN UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  POU_1 UniProtKB/TrEMBL
  POU_2 UniProtKB/TrEMBL
  POU_3 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  POU UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain-like UniProtKB/TrEMBL
  lambda repressor-like DNA-binding domains UniProtKB/TrEMBL
UniProt A0AAX6P5P4 ENTREZGENE, UniProtKB/TrEMBL