Znrf1 (zinc and ring finger 1) - Rat Genome Database

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Gene: Znrf1 (zinc and ring finger 1) Heterocephalus glaber
Analyze
Symbol: Znrf1
Name: zinc and ring finger 1
RGD ID: 18913813
Description: ENCODES a protein that exhibits ubiquitin-protein transferase activity (ortholog); INVOLVED IN positive regulation of autophagosome-lysosome fusion (ortholog); positive regulation of toll-like receptor 4 signaling pathway (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase ZNRF1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474611,848,425 - 11,954,784 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474611,847,627 - 11,954,637 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
cytosol  (ISO)
endosome  (IEA)
lysosome  (IEA)
membrane  (IEA)
synaptic vesicle membrane  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
Znrf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474611,848,425 - 11,954,784 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474611,847,627 - 11,954,637 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
ZNRF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381674,999,024 - 75,110,994 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1674,999,014 - 75,110,994 (+)Ensemblhg38GRCh38
GRCh371675,032,922 - 75,144,892 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361673,590,416 - 73,702,393 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341673,590,415 - 73,702,393NCBI
Celera1659,325,881 - 59,437,794 (+)NCBICelera
Cytogenetic Map16q23.1NCBI
HuRef1660,784,212 - 60,895,817 (+)NCBIHuRef
CHM1_11676,445,151 - 76,557,062 (+)NCBICHM1_1
T2T-CHM13v2.01681,045,795 - 81,157,694 (+)NCBIT2T-CHM13v2.0
Znrf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398112,262,652 - 112,352,352 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8112,262,729 - 112,352,662 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388111,536,484 - 111,625,720 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8111,536,097 - 111,626,030 (+)Ensemblmm10GRCm38
MGSCv378114,060,540 - 114,149,930 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368114,423,515 - 114,510,451 (+)NCBIMGSCv36mm8
Celera8115,764,236 - 115,853,550 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map857.98NCBI
Znrf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81956,403,816 - 56,490,901 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1956,405,728 - 56,490,881 (+)EnsemblGRCr8
mRatBN7.21939,496,414 - 39,581,600 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1939,496,527 - 39,580,969 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1946,296,356 - 46,380,722 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,949,689 - 47,034,049 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01949,254,321 - 49,338,675 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1950,177,765 - 50,262,129 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1948,301,266 - 48,385,620 (+)NCBILyon_Normotensive
Lyon_Hypertensive1950,176,012 - 50,260,373 (+)NCBILyon_Hypertensive
F344_StmMcwi1947,936,539 - 48,021,703 (+)NCBIF344_StmMcwi
Rnor_6.01943,750,205 - 43,834,962 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1943,750,278 - 43,832,878 (+)Ensemblrn6Rnor6.0
Rnor_5.01954,557,442 - 54,642,129 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41941,455,386 - 41,537,955 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1938,875,649 - 38,959,752 (+)NCBICelera
Cytogenetic Map19q12NCBI
Znrf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554842,468,392 - 2,566,539 (-)Ensembl
ChiLan1.0NW_0049554842,468,392 - 2,566,539 (-)NCBIChiLan1.0ChiLan1.0
ZNRF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21884,716,474 - 84,828,132 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11690,638,445 - 90,750,117 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01655,567,875 - 55,679,524 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11674,920,141 - 75,030,933 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1674,920,141 - 75,030,933 (+)EnsemblpanPan2panpan1.1
ZNRF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1575,594,465 - 75,698,164 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl575,595,200 - 75,698,170 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha575,570,792 - 75,674,762 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0575,950,710 - 76,054,735 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl575,951,488 - 76,054,338 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1575,855,151 - 75,958,882 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0575,677,829 - 75,781,679 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0576,170,074 - 76,273,880 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Znrf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934935,670,243 - 35,774,914 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647523,814,194 - 23,916,530 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647523,814,200 - 23,918,871 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNRF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1612,555,655 - 12,668,807 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2612,430,136 - 12,432,305 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZNRF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1560,568,582 - 60,590,699 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604715,469,480 - 15,585,200 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znrf1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11731,222,687 - 31,308,863 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000020212   ⟹   ENSHGLP00000020012
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474611,848,425 - 11,954,784 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000020213   ⟹   ENSHGLP00000020013
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474611,850,694 - 11,954,142 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000020214   ⟹   ENSHGLP00000020014
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474611,850,694 - 11,952,898 (-)Ensembl
RefSeq Acc Id: XM_004842845   ⟹   XP_004842902
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474611,848,425 - 11,954,627 (-)NCBI
RefSeq Acc Id: XM_004842846   ⟹   XP_004842903
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474611,847,627 - 11,954,637 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004842902 (Get FASTA)   NCBI Sequence Viewer  
  XP_004842903 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020012
RefSeq Acc Id: XP_004842903   ⟸   XM_004842846
- UniProtKB: A0AAX6P3L0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842902   ⟸   XM_004842845
- UniProtKB: A0AAX6P3L0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000020013   ⟸   ENSHGLT00000020213
Ensembl Acc Id: ENSHGLP00000020012   ⟸   ENSHGLT00000020212
Ensembl Acc Id: ENSHGLP00000020014   ⟸   ENSHGLT00000020214


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014332 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000020212 ENTREZGENE
Gene3D-CATH Zinc/RING finger domain, C3HC4 (zinc finger) UniProtKB/TrEMBL
InterPro Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  ZNRF_ubiq-protein_ligase UniProtKB/TrEMBL
KEGG Report hgl:101711624 UniProtKB/TrEMBL
NCBI Gene Znrf1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE ZNRF1 UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN UniProtKB/TrEMBL
Pfam zf-RING_2 UniProtKB/TrEMBL
PROSITE ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0AAX6P3L0 ENTREZGENE, UniProtKB/TrEMBL