Ctu2 (cytosolic thiouridylase subunit 2) - Rat Genome Database

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Gene: Ctu2 (cytosolic thiouridylase subunit 2) Heterocephalus glaber
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Symbol: Ctu2
Name: cytosolic thiouridylase subunit 2
RGD ID: 18913400
Description: ENCODES a protein that exhibits nucleotidyltransferase activity (inferred); sulfurtransferase activity (inferred); tRNA binding (inferred); INVOLVED IN protein urmylation (inferred); tRNA processing (inferred); tRNA thio-modification (inferred); ASSOCIATED WITH Animal Disease Models (ortholog); Breast Neoplasms (ortholog); CAKUT (ortholog); FOUND IN protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Cytoplasmic tRNA 2-thiolation protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746871,668 - 877,719 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624746871,707 - 878,047 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ctu2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746871,668 - 877,719 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624746871,707 - 878,047 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
CTU2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381688,706,503 - 88,715,396 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1688,706,473 - 88,715,396 (+)Ensemblhg38GRCh38
GRCh371688,772,911 - 88,781,804 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,300,392 - 87,309,295 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1673,276,731 - 73,278,805 (-)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1674,467,287 - 74,477,681 (+)NCBIHuRef
CHM1_11690,184,233 - 90,193,064 (+)NCBICHM1_1
T2T-CHM13v2.01694,775,662 - 94,785,864 (+)NCBIT2T-CHM13v2.0
Ctu2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,202,882 - 123,209,831 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,202,882 - 123,210,877 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388122,476,068 - 122,483,092 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,476,143 - 122,484,138 (+)Ensemblmm10GRCm38
MGSCv378125,000,043 - 125,006,992 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368125,362,280 - 125,367,837 (+)NCBIMGSCv36mm8
MGSCv368122,545,627 - 122,551,185 (+)NCBIMGSCv36mm8
Celera8126,705,199 - 126,712,124 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map871.26NCBI
Ctu2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,447,762 - 67,453,169 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1967,447,487 - 67,453,163 (+)EnsemblGRCr8
mRatBN7.21950,539,184 - 50,544,629 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,539,352 - 50,544,623 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1957,334,554 - 57,339,522 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,014,331 - 58,019,558 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,233,177 - 60,238,145 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1961,246,223 - 61,251,580 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1959,368,897 - 59,374,124 (+)NCBILyon_Normotensive
Lyon_Hypertensive1961,242,358 - 61,247,585 (+)NCBILyon_Hypertensive
F344_StmMcwi1958,977,315 - 58,982,283 (+)NCBIF344_StmMcwi
Rnor_6.01955,300,531 - 55,305,543 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,300,395 - 55,305,702 (+)Ensemblrn6Rnor6.0
Rnor_5.01966,009,931 - 66,014,988 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41952,765,786 - 52,771,016 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1949,778,881 - 49,784,108 (+)NCBICelera
Cytogenetic Map19q12NCBI
Ctu2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555412,610,021 - 2,618,197 (+)NCBIChiLan1.0ChiLan1.0
CTU2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,479,814 - 98,488,599 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,391,891 - 104,400,757 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,419,811 - 69,428,500 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,080,476 - 89,088,363 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,079,132 - 89,088,231 (+)EnsemblpanPan2panpan1.1
CTU2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,640,389 - 64,647,298 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,640,389 - 64,647,215 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha564,651,709 - 64,658,603 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0564,860,459 - 64,867,333 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,860,459 - 64,867,295 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,886,634 - 64,893,522 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,718,200 - 64,725,080 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0565,124,376 - 65,131,248 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ctu2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,225,667 - 25,232,488 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641980,533 - 984,506 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936641980,493 - 986,015 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTU2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6964,566 - 976,832 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16964,551 - 976,881 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CTU2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,091,156 - 74,100,941 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,091,258 - 74,100,573 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660471,579,212 - 1,589,006 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctu2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11742,115,931 - 42,120,741 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000022630   ⟹   ENSHGLP00000022418
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624746871,668 - 877,719 (-)Ensembl
RefSeq Acc Id: XM_004842681   ⟹   XP_004842738
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746871,707 - 878,045 (-)NCBI
RefSeq Acc Id: XM_021256577   ⟹   XP_021112236
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746871,707 - 878,045 (-)NCBI
RefSeq Acc Id: XM_021256578   ⟹   XP_021112237
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746871,707 - 878,045 (-)NCBI
RefSeq Acc Id: XR_002394217
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746872,136 - 878,047 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004842738 (Get FASTA)   NCBI Sequence Viewer  
  XP_021112236 (Get FASTA)   NCBI Sequence Viewer  
  XP_021112237 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB15852 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000022418
RefSeq Acc Id: XP_004842738   ⟸   XM_004842681
- Peptide Label: isoform X2
- UniProtKB: G5C2U1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112237   ⟸   XM_021256578
- Peptide Label: isoform X3
- UniProtKB: A0AAX6SWH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112236   ⟸   XM_021256577
- Peptide Label: isoform X1
- UniProtKB: A0AAX6SUX5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000022418   ⟸   ENSHGLT00000022630


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015988 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022630 ENTREZGENE
Gene3D-CATH 3.40.50.620 UniProtKB/TrEMBL
InterPro CTU2 UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
KEGG Report hgl:101715059 UniProtKB/TrEMBL
NCBI Gene Ctu2 ENTREZGENE
PANTHER CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 UniProtKB/TrEMBL
  PTHR20882 UniProtKB/TrEMBL
Pfam CTU2 UniProtKB/TrEMBL
Superfamily-SCOP Adenine nucleotide alpha hydrolases-like UniProtKB/TrEMBL
UniProt A0AAX6SUX5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SWH6 ENTREZGENE, UniProtKB/TrEMBL
  G5C2U1 ENTREZGENE, UniProtKB/TrEMBL