Nfat5 (nuclear factor of activated T cells 5) - Rat Genome Database

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Gene: Nfat5 (nuclear factor of activated T cells 5) Heterocephalus glaber
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Symbol: Nfat5
Name: nuclear factor of activated T cells 5
RGD ID: 18910636
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN positive regulation of gene expression (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of calcineurin-NFAT signaling cascade (ortholog); ASSOCIATED WITH autoimmune disease of gastrointestinal tract (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear factor of activated T-cells 5; nuclear factor of activated T-cells 5, tonicity-responsive
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474616,684,407 - 16,818,430 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474616,684,556 - 16,818,321 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nfat5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474616,684,407 - 16,818,430 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474616,684,556 - 16,818,321 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
NFAT5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381669,565,966 - 69,704,654 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1669,565,094 - 69,704,666 (+)Ensemblhg38GRCh38
GRCh371669,599,869 - 69,738,557 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361668,156,498 - 68,296,054 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1654,113,571 - 54,253,111 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1655,478,121 - 55,616,752 (+)NCBIHuRef
CHM1_11671,007,818 - 71,146,456 (+)NCBICHM1_1
T2T-CHM13v2.01675,368,170 - 75,506,838 (+)NCBIT2T-CHM13v2.0
Nfat5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398108,020,072 - 108,106,149 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8108,020,102 - 108,106,149 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388107,293,435 - 107,379,517 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8107,293,470 - 107,379,517 (+)Ensemblmm10GRCm38
MGSCv378109,817,370 - 109,903,417 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368110,182,991 - 110,268,646 (+)NCBIMGSCv36mm8
Celera8111,523,092 - 111,609,223 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.93NCBI
Nfat5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81952,108,982 - 52,196,418 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1952,109,483 - 52,196,418 (+)EnsemblGRCr8
mRatBN7.21935,199,737 - 35,286,675 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1935,199,016 - 35,286,675 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1942,015,199 - 42,102,135 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01942,668,550 - 42,755,492 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01944,973,511 - 45,060,409 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1945,896,779 - 45,983,720 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1944,021,633 - 44,108,565 (+)NCBILyon_Normotensive
Lyon_Hypertensive1945,894,987 - 45,981,919 (+)NCBILyon_Hypertensive
F344_StmMcwi1943,650,202 - 43,737,132 (+)NCBIF344_StmMcwi
Rnor_6.01938,446,059 - 38,533,735 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1938,446,059 - 38,533,735 (-)Ensemblrn6Rnor6.0
Rnor_5.01950,363,699 - 50,398,311 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01949,320,570 - 49,403,625 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41937,154,326 - 37,242,191 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1934,621,583 - 34,708,117 (+)NCBICelera
RGSC_v3.11937,093,773 - 37,238,503 (+)NCBI
Cytogenetic Map19q12NCBI
Nfat5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554847,034,799 - 7,142,883 (-)Ensembl
ChiLan1.0NW_0049554847,034,799 - 7,142,883 (-)NCBIChiLan1.0ChiLan1.0
NFAT5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21879,112,502 - 79,254,607 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11685,024,664 - 85,166,745 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01649,942,461 - 50,080,519 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11669,327,470 - 69,462,251 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1669,327,470 - 69,462,251 (+)EnsemblpanPan2panpan1.1
NFAT5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1579,995,292 - 80,115,116 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl580,003,587 - 80,115,096 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha579,984,111 - 80,105,721 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0580,425,837 - 80,547,558 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl580,432,528 - 80,548,712 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1580,253,618 - 80,375,936 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0579,943,167 - 80,064,783 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0580,576,081 - 80,698,426 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nfat5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934939,830,178 - 39,928,927 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647519,660,201 - 19,758,930 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647519,658,917 - 19,758,936 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFAT5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl617,313,413 - 17,434,940 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1617,313,511 - 17,434,951 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2616,252,167 - 16,381,341 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NFAT5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1557,705,022 - 57,838,569 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl557,709,277 - 57,838,704 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604720,430,610 - 20,568,859 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfat5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11727,017,478 - 27,098,664 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004842937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004842938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004842939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004842940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013071520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01026032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01026033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01026034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01026035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01026036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01026037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01026038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01026039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH165628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000020694   ⟹   ENSHGLP00000020492
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474616,684,407 - 16,818,430 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000020695   ⟹   ENSHGLP00000020493
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474616,707,380 - 16,818,232 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000020696   ⟹   ENSHGLP00000020494
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474616,707,380 - 16,818,232 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000020697   ⟹   ENSHGLP00000020495
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474616,709,450 - 16,751,512 (-)Ensembl
RefSeq Acc Id: XM_004842937   ⟹   XP_004842994
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474616,700,714 - 16,818,318 (-)NCBI
RefSeq Acc Id: XM_004842938   ⟹   XP_004842995
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474616,700,714 - 16,818,320 (-)NCBI
RefSeq Acc Id: XM_004842939   ⟹   XP_004842996
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474616,700,714 - 16,818,317 (-)NCBI
RefSeq Acc Id: XM_004842940   ⟹   XP_004842997
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474616,700,714 - 16,816,150 (-)NCBI
RefSeq Acc Id: XM_013071520   ⟹   XP_012926974
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474616,700,714 - 16,818,319 (-)NCBI
RefSeq Acc Id: XM_021256776   ⟹   XP_021112435
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474616,684,556 - 16,818,321 (-)NCBI
RefSeq Acc Id: XM_021256777   ⟹   XP_021112436
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474616,700,714 - 16,748,927 (-)NCBI
RefSeq Acc Id: XP_021112435   ⟸   XM_021256776
- Peptide Label: isoform X1
- UniProtKB: G5AK40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842995   ⟸   XM_004842938
- Peptide Label: isoform X2
- UniProtKB: A0AAX6P3B1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926974   ⟸   XM_013071520
- Peptide Label: isoform X4
- UniProtKB: A0AAX6QT87 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842994   ⟸   XM_004842937
- Peptide Label: isoform X1
- UniProtKB: G5AK40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842996   ⟸   XM_004842939
- Peptide Label: isoform X3
- UniProtKB: A0AAX6P3Y2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842997   ⟸   XM_004842940
- Peptide Label: isoform X5
- UniProtKB: A0AAX6P3Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112436   ⟸   XM_021256777
- Peptide Label: isoform X6
- UniProtKB: A0AAX6SSU0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000020493   ⟸   ENSHGLT00000020695
Ensembl Acc Id: ENSHGLP00000020494   ⟸   ENSHGLT00000020696
Ensembl Acc Id: ENSHGLP00000020495   ⟸   ENSHGLT00000020697
Ensembl Acc Id: ENSHGLP00000020492   ⟸   ENSHGLT00000020694


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014649 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000020694 ENTREZGENE
  ENSHGLT00000020695 ENTREZGENE
  ENSHGLT00000020696 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  2.60.40.340 UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  IPT_dom UniProtKB/TrEMBL
  NFAT UniProtKB/TrEMBL
  NFAT5 UniProtKB/TrEMBL
  p53-like_TF_DNA-bd UniProtKB/TrEMBL
  RHD_dimer UniProtKB/TrEMBL
  RHD_DNA_bind_dom UniProtKB/TrEMBL
  RHD_DNA_bind_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101711867 UniProtKB/TrEMBL
NCBI Gene Nfat5 ENTREZGENE
PANTHER PTHR12533 UniProtKB/TrEMBL
  PTHR12533:SF10 UniProtKB/TrEMBL
Pfam RHD_dimer UniProtKB/TrEMBL
  RHD_DNA_bind UniProtKB/TrEMBL
PRINTS NUCFACTORATC UniProtKB/TrEMBL
PROSITE REL_2 UniProtKB/TrEMBL
SMART IPT UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0AAX6P3B1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6P3Y1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6P3Y2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QT87 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SSU0 ENTREZGENE, UniProtKB/TrEMBL
  G5AK40 ENTREZGENE, UniProtKB/TrEMBL