Fahd2a (fumarylacetoacetate hydrolase domain-containing protein 2A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Fahd2a (fumarylacetoacetate hydrolase domain-containing protein 2A) Heterocephalus glaber
Analyze
Symbol: Fahd2a
Name: fumarylacetoacetate hydrolase domain-containing protein 2A
RGD ID: 18902525
Description: ENCODES a protein that exhibits catalytic activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN oxaloacetate metabolic process (inferred); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fumarylacetoacetate hydrolase domain containing 2A; LOC101700516
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247492,138,410 - 2,152,673 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247492,138,188 - 2,152,673 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Fahd2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247492,138,410 - 2,152,673 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247492,138,188 - 2,152,673 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
FAHD2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38295,402,708 - 95,421,656 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl295,402,691 - 95,416,616 (+)Ensemblhg38GRCh38
GRCh37296,068,456 - 96,082,364 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36295,432,175 - 95,442,606 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34295,490,321 - 95,500,753NCBI
Celera290,421,569 - 90,432,000 (+)NCBICelera
Cytogenetic Map2q11.1NCBI
HuRef290,095,394 - 90,105,821 (+)NCBIHuRef
CHM1_1296,072,763 - 96,083,194 (+)NCBICHM1_1
T2T-CHM13v2.0295,909,154 - 95,928,138 (+)NCBIT2T-CHM13v2.0
Fahd2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,278,135 - 127,286,491 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2127,278,135 - 127,286,485 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382127,436,215 - 127,444,571 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2127,436,215 - 127,444,565 (-)Ensemblmm10GRCm38
MGSCv372127,261,951 - 127,270,301 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362127,127,656 - 127,135,946 (-)NCBIMGSCv36mm8
Celera2128,678,251 - 128,686,589 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.01NCBI
Fahd2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83135,110,480 - 135,118,653 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3135,109,482 - 135,118,853 (-)EnsemblGRCr8
mRatBN7.23114,657,176 - 114,665,349 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,655,865 - 114,665,356 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3118,546,518 - 118,554,707 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03127,142,077 - 127,150,266 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,802,450 - 124,810,639 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03120,003,215 - 120,011,392 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3120,002,364 - 120,011,364 (-)Ensemblrn6Rnor6.0
Rnor_5.03127,321,203 - 127,329,383 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43114,939,359 - 114,947,515 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3113,495,646 - 113,503,802 (-)NCBICelera
Cytogenetic Map3q36NCBI
Fahd2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554703,624,462 - 3,632,949 (+)Ensembl
ChiLan1.0NW_0049554703,624,462 - 3,632,949 (+)NCBIChiLan1.0ChiLan1.0
FAHD2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21232,877,620 - 32,890,484 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A32,879,283 - 32,893,235 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A103,989,665 - 104,001,885 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A96,317,574 - 96,321,008 (+)NCBIPanPan1.1PanPan1.1panPan2
Fahd2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,923,012 - 82,930,693 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936744175,882 - 183,675 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936744175,948 - 183,631 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100522130
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1345,857,494 - 45,888,353 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2348,458,590 - 48,487,135 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103241057
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114437,719 - 446,738 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14437,662 - 446,552 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023667445552 - 1,309 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fahd2a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15106,221,513 - 106,229,474 (-)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000006079   ⟹   ENSHGLP00000006005
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247492,138,410 - 2,152,673 (+)Ensembl
RefSeq Acc Id: XM_004844346   ⟹   XP_004844403
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247492,138,188 - 2,152,673 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004844403 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99047 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006005
GenBank Protein JAO00892 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004844403   ⟸   XM_004844346
- UniProtKB: G5APT7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006005   ⟸   ENSHGLT00000006079


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004391 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000006079 ENTREZGENE
Gene3D-CATH 3.90.850.10 UniProtKB/TrEMBL
InterPro FAH UniProtKB/TrEMBL
  Fumarylacetoacetase-like_C UniProtKB/TrEMBL
  Fumarylacetoacetase_C_sf UniProtKB/TrEMBL
KEGG Report hgl:101700516 UniProtKB/TrEMBL
NCBI Gene LOC101700516 ENTREZGENE
PANTHER FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A UniProtKB/TrEMBL
  FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED UniProtKB/TrEMBL
Pfam FAA_hydrolase UniProtKB/TrEMBL
Superfamily-SCOP SSF56529 UniProtKB/TrEMBL
UniProt G5APT7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-02-24 Fahd2a  fumarylacetoacetate hydrolase domain-containing protein 2A  LOC101700516  fumarylacetoacetate hydrolase domain-containing protein 2A  Symbol changed 629549 APPROVED