TBC1D5 (TBC1 domain family member 5) - Rat Genome Database

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Gene: TBC1D5 (TBC1 domain family member 5) Sus scrofa
Analyze
Symbol: TBC1D5
Name: TBC1 domain family member 5
RGD ID: 14091805
Description: ENCODES a protein that exhibits AP-2 adaptor complex binding (inferred); GTPase activator activity (inferred); protein-containing complex binding (inferred); INVOLVED IN regulation of cilium assembly (ortholog); PARTICIPATES IN retromer-mediated pathway; FOUND IN AP-2 adaptor complex (inferred); Atg1/ULK1 kinase complex (inferred); autophagosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl134,201,255 - 4,633,312 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1134,191,544 - 4,738,448 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2134,510,127 - 4,870,221 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TBC1D5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl134,201,255 - 4,633,312 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1134,191,544 - 4,738,448 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2134,510,127 - 4,870,221 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38317,157,162 - 17,742,631 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl317,157,162 - 18,444,817 (-)Ensemblhg38GRCh38
GRCh37317,198,654 - 17,784,123 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36317,174,903 - 17,757,403 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34317,174,902 - 17,757,403NCBI
Celera317,137,647 - 17,722,084 (-)NCBICelera
Cytogenetic Map3p24.3NCBI
HuRef317,133,466 - 17,719,908 (-)NCBIHuRef
CHM1_1317,150,453 - 17,736,433 (-)NCBICHM1_1
T2T-CHM13v2.0317,159,342 - 17,744,665 (-)NCBIT2T-CHM13v2.0
Tbc1d5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391751,040,155 - 51,488,228 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1751,040,152 - 51,486,380 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381750,733,124 - 51,181,199 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1750,733,124 - 51,179,352 (-)Ensemblmm10GRCm38
MGSCv371750,872,452 - 51,318,674 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361750,198,695 - 50,644,264 (-)NCBIMGSCv36mm8
Celera1754,189,254 - 54,641,895 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1726.47NCBI
Tbc1d5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr893,740,032 - 4,256,971 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl93,750,325 - 4,253,581 (-)EnsemblGRCr8
mRatBN7.293,503,328 - 4,017,131 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl93,513,623 - 4,016,913 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx94,680,753 - 5,200,179 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.099,852,802 - 10,372,136 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.098,985,996 - 9,505,071 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd94,669,173 - 5,172,397 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive94,226,271 - 4,729,701 (-)NCBILyon_Normotensive
Lyon_Hypertensive94,281,171 - 4,784,544 (-)NCBILyon_Hypertensive
F344_StmMcwi913,457,210 - 13,977,342 (+)NCBIF344_StmMcwi
Rnor_6.091,144,641 - 1,747,732 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl91,145,700 - 1,746,397 (+)Ensemblrn6Rnor6.0
Rnor_5.091,106,437 - 1,325,473 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.091,393,160 - 1,704,245 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.494,112,690 - 4,650,663 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera9417,936 - 917,218 (-)NCBICelera
Cytogenetic Map9q11NCBI
Tbc1d5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554309,410,475 - 9,940,460 (-)Ensembl
ChiLan1.0NW_0049554309,411,865 - 9,966,710 (-)NCBIChiLan1.0ChiLan1.0
TBC1D5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2217,139,987 - 17,735,423 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1317,144,751 - 17,740,187 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0317,080,589 - 17,664,776 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1317,416,307 - 17,999,493 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl317,416,307 - 17,768,132 (-)EnsemblpanPan2panpan1.1
TBC1D5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12325,206,825 - 25,758,026 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2325,254,448 - 25,757,385 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2325,200,607 - 25,733,279 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02325,705,164 - 26,258,261 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2325,705,188 - 26,258,001 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12325,413,938 - 25,960,236 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02325,475,448 - 26,020,155 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02325,726,585 - 26,269,437 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tbc1d5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118176,730,088 - 177,155,898 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364739,868,430 - 10,188,484 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364739,868,657 - 10,294,554 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11562,009,952 - 62,569,187 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1562,006,701 - 62,358,449 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604134,998,278 - 35,563,925 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbc1d5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248212,398,042 - 2,806,263 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248212,398,211 - 3,068,212 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Tbc1d5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1157,535,151 - 57,536,183 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in TBC1D5
18506 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000012264   ⟹   ENSSSCP00000011949
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl134,201,248 - 4,738,397 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000012265   ⟹   ENSSSCP00000011950
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl134,035,026 - 4,738,367 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000048133   ⟹   ENSSSCP00000053319
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl134,201,334 - 4,738,367 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000060482   ⟹   ENSSSCP00000046266
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl134,201,255 - 4,633,312 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000071785   ⟹   ENSSSCP00000060017
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl134,222,537 - 4,444,172 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000086986   ⟹   ENSSSCP00000064981
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl134,201,255 - 4,633,312 (-)Ensembl
RefSeq Acc Id: XM_021069679   ⟹   XP_020925338
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1134,191,544 - 4,738,447 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069680   ⟹   XP_020925339
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1134,191,544 - 4,738,448 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069681   ⟹   XP_020925340
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1134,191,544 - 4,738,448 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069682   ⟹   XP_020925341
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1134,191,544 - 4,738,448 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069683   ⟹   XP_020925342
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1134,191,544 - 4,631,254 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069684   ⟹   XP_020925343
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1134,191,544 - 4,608,683 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069685   ⟹   XP_020925344
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1134,191,544 - 4,450,225 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069686   ⟹   XP_020925345
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1134,201,103 - 4,608,684 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020925340   ⟸   XM_021069681
- Peptide Label: isoform X1
- UniProtKB: A0A8D0UWS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925339   ⟸   XM_021069680
- Peptide Label: isoform X1
- UniProtKB: A0A8D0UWS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925341   ⟸   XM_021069682
- Peptide Label: isoform X1
- UniProtKB: A0A8D0UWS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925338   ⟸   XM_021069679
- Peptide Label: isoform X1
- UniProtKB: A0A8D0UWS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925342   ⟸   XM_021069683
- Peptide Label: isoform X1
- UniProtKB: A0A8D0UWS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925343   ⟸   XM_021069684
- Peptide Label: isoform X1
- UniProtKB: A0A8D0UWS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925344   ⟸   XM_021069685
- Peptide Label: isoform X2
- UniProtKB: A0A4X1UR77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925345   ⟸   XM_021069686
- Peptide Label: isoform X3
- UniProtKB: A0A8D1S6I0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000011949   ⟸   ENSSSCT00000012264
Ensembl Acc Id: ENSSSCP00000011950   ⟸   ENSSSCT00000012265
Ensembl Acc Id: ENSSSCP00000046266   ⟸   ENSSSCT00000060482
Ensembl Acc Id: ENSSSCP00000060017   ⟸   ENSSSCT00000071785
Ensembl Acc Id: ENSSSCP00000053319   ⟸   ENSSSCT00000048133
Ensembl Acc Id: ENSSSCP00000064981   ⟸   ENSSSCT00000086986
Protein Domains
Rab-GAP TBC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011199 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025058645 UniProtKB/TrEMBL
  ENSSSCG00055027647 UniProtKB/TrEMBL
  ENSSSCG00070018701 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000060482.3 UniProtKB/TrEMBL
  ENSSSCT00000071785.1 UniProtKB/TrEMBL
  ENSSSCT00000086986 ENTREZGENE
  ENSSSCT00000086986.2 UniProtKB/TrEMBL
  ENSSSCT00025081235.1 UniProtKB/TrEMBL
  ENSSSCT00025082493.1 UniProtKB/TrEMBL
  ENSSSCT00055055040.1 UniProtKB/TrEMBL
  ENSSSCT00070037122.1 UniProtKB/TrEMBL
Gene3D-CATH putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro Rab-GTPase-TBC_dom UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/TrEMBL
NCBI Gene TBC1D5 ENTREZGENE
PANTHER TBC1 DOMAIN FAMILY MEMBER 5 UniProtKB/TrEMBL
  TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
Pfam RabGAP-TBC UniProtKB/TrEMBL
PROSITE TBC_RABGAP UniProtKB/TrEMBL
SMART TBC UniProtKB/TrEMBL
Superfamily-SCOP beta-sandwich domain of Sec23/24 UniProtKB/TrEMBL
  SSF47923 UniProtKB/TrEMBL
UniProt A0A287AQT3_PIG UniProtKB/TrEMBL
  A0A4X1UR77 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QJK6_PIG UniProtKB/TrEMBL
  A0A5G2QP04_PIG UniProtKB/TrEMBL
  A0A8D0UWS4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1S6I0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:98360 ENTREZGENE