SLFN11 (schlafen family member 11) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: SLFN11 (schlafen family member 11) Sus scrofa
Analyze
Symbol: SLFN11
Name: schlafen family member 11
RGD ID: 13929227
Description: ENCODES a protein that exhibits RNA endonuclease activity (ortholog); zinc ion binding (ortholog); INVOLVED IN rRNA catabolic process (ortholog); tRNA decay (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,974,730 - 39,996,255 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11239,974,519 - 39,996,257 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,461,436 - 41,503,336 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202   PMID:37293979  


Genomics

Comparative Map Data
SLFN11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,974,730 - 39,996,255 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11239,974,519 - 39,996,257 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,461,436 - 41,503,336 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLFN11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381735,350,305 - 35,373,621 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1735,350,305 - 35,373,701 (-)Ensemblhg38GRCh38
GRCh371733,677,324 - 33,700,640 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361730,701,437 - 30,724,833 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1730,587,468 - 30,610,868 (-)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1729,862,347 - 29,885,745 (-)NCBIHuRef
CHM1_11733,741,641 - 33,765,042 (-)NCBICHM1_1
T2T-CHM13v2.01736,298,255 - 36,321,577 (-)NCBIT2T-CHM13v2.0
Slfn9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391182,865,142 - 82,883,041 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1182,869,216 - 82,882,656 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381182,974,316 - 82,991,830 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,978,390 - 82,991,830 (-)Ensemblmm10GRCm38
MGSCv371182,793,805 - 82,805,332 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361182,796,498 - 82,808,025 (-)NCBIMGSCv36mm8
Celera1192,607,183 - 92,618,506 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1150.3NCBI
Slfn9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81068,406,641 - 68,420,062 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1068,406,642 - 68,421,134 (-)EnsemblGRCr8
mRatBN7.21067,909,105 - 67,955,912 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1067,909,106 - 67,925,383 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1072,529,137 - 72,542,558 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01072,034,519 - 72,047,940 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01067,498,563 - 67,511,986 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1071,278,495 - 71,291,916 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1071,999,951 - 72,013,372 (-)NCBILyon_Normotensive
Lyon_Hypertensive1073,674,038 - 73,687,459 (-)NCBILyon_Hypertensive
F344_StmMcwi1073,562,581 - 73,576,003 (-)NCBIF344_StmMcwi
Rnor_6.01070,326,157 - 70,343,024 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1070,326,157 - 70,342,492 (-)Ensemblrn6Rnor6.0
Rnor_5.01069,956,875 - 69,972,497 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41071,192,184 - 71,205,605 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1066,853,364 - 66,866,767 (-)NCBICelera
RGSC_v3.11071,205,850 - 71,219,281 (-)NCBI
Cytogenetic Map10q26NCBI
Slfn11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554819,885,607 - 9,900,330 (-)Ensembl
ChiLan1.0NW_0049554819,885,798 - 9,900,330 (-)NCBIChiLan1.0ChiLan1.0
SLFN11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21929,093,171 - 29,116,382 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11730,974,154 - 30,999,272 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01721,412,361 - 21,436,650 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11721,705,803 - 21,728,810 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1721,715,569 - 21,727,019 (+)EnsemblpanPan2panpan1.1
SLFN11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11628,819,647 - 28,842,121 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1628,817,666 - 28,842,065 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660751,142,108 - 1,168,767 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slfn11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1987,524,685 - 87,536,460 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in SLFN11
697 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000051594   ⟹   ENSSSCP00000040143
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1239,974,730 - 39,992,685 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000066576   ⟹   ENSSSCP00000072717
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1239,974,792 - 39,996,255 (+)Ensembl
RefSeq Acc Id: XM_021067411   ⟹   XP_020923070
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11239,974,734 - 39,996,257 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021067412   ⟹   XP_020923071
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11239,974,519 - 39,996,019 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020923071   ⟸   XM_021067412
- Peptide Label: isoform X2
- UniProtKB: A0A8D0U4N7 (UniProtKB/TrEMBL),   A0A8D1G3C6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020923070   ⟸   XM_021067411
- Peptide Label: isoform X1
- UniProtKB: A0A5G2RKN9 (UniProtKB/TrEMBL),   A0A8D0U4N7 (UniProtKB/TrEMBL),   A0A8D1G3C6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000040143   ⟸   ENSSSCT00000051594
Ensembl Acc Id: ENSSSCP00000072717   ⟸   ENSSSCT00000066576

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000032652 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015045402 UniProtKB/TrEMBL
  ENSSSCG00035058286 UniProtKB/TrEMBL
  ENSSSCG00040075212 UniProtKB/TrEMBL
  ENSSSCG00070007345 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000051594.2 UniProtKB/TrEMBL
  ENSSSCT00000066576 ENTREZGENE
  ENSSSCT00000066576.1 UniProtKB/TrEMBL
  ENSSSCT00015060680.1 UniProtKB/TrEMBL
  ENSSSCT00035078013.1 UniProtKB/TrEMBL
  ENSSSCT00040104236.1 UniProtKB/TrEMBL
  ENSSSCT00070014130.1 UniProtKB/TrEMBL
  ENSSSCT00070014134.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.950.30 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DUF2075 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Poxin-SLFN/SLFN_N UniProtKB/TrEMBL
  Schlafen UniProtKB/TrEMBL
  Schlafen_AlbA_2_dom UniProtKB/TrEMBL
  Schlafen_AlbA_2_dom_sf UniProtKB/TrEMBL
  SLFN_GTPase-like UniProtKB/TrEMBL
NCBI Gene SLFN11 ENTREZGENE
PANTHER PTHR12155 UniProtKB/TrEMBL
  SCHLAFEN FAMILY MEMBER 13 UniProtKB/TrEMBL
Pfam AlbA_2 UniProtKB/TrEMBL
  B3R UniProtKB/TrEMBL
  DUF2075 UniProtKB/TrEMBL
  SLFN_GTPase-like UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287A8K2_PIG UniProtKB/TrEMBL
  A0A4X1T6T4_PIG UniProtKB/TrEMBL
  A0A4X1T9B9_PIG UniProtKB/TrEMBL
  A0A5G2RKN9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0U4N7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1G3C6 ENTREZGENE, UniProtKB/TrEMBL