UNC50 (unc-50 inner nuclear membrane RNA binding protein) - Rat Genome Database

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Gene: UNC50 (unc-50 inner nuclear membrane RNA binding protein) Sus scrofa
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Symbol: UNC50
Name: unc-50 inner nuclear membrane RNA binding protein
RGD ID: 13878854
Description: ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN protein localization to cell surface (ortholog); ASSOCIATED WITH fetal akinesia deformation sequence syndrome 1 (ortholog); FOUND IN Golgi apparatus (inferred); nuclear inner membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein unc-50 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl355,667,826 - 55,676,978 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1355,667,821 - 55,676,995 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2358,220,278 - 58,229,446 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
UNC50
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl355,667,826 - 55,676,978 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1355,667,821 - 55,676,995 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2358,220,278 - 58,229,446 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UNC50
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38298,608,589 - 98,618,515 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl298,608,434 - 98,618,515 (+)Ensemblhg38GRCh38
GRCh37299,225,052 - 99,234,978 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36298,591,474 - 98,601,410 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34298,683,559 - 98,693,493NCBI
Celera293,428,766 - 93,438,703 (+)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef292,989,630 - 92,999,566 (+)NCBIHuRef
CHM1_1299,229,365 - 99,239,301 (+)NCBICHM1_1
T2T-CHM13v2.0299,066,916 - 99,076,837 (+)NCBIT2T-CHM13v2.0
Unc50
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39137,469,220 - 37,478,068 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl137,469,220 - 37,478,205 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38137,430,139 - 37,438,987 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl137,430,139 - 37,439,124 (+)Ensemblmm10GRCm38
MGSCv37137,487,017 - 37,495,969 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36137,374,718 - 37,383,670 (+)NCBIMGSCv36mm8
Celera137,212,232 - 37,220,930 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map115.46NCBI
Unc50
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8947,160,723 - 47,169,710 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl947,160,796 - 47,168,688 (+)EnsemblGRCr8
mRatBN7.2939,664,944 - 39,674,369 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl939,664,971 - 39,672,890 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx948,161,080 - 48,168,954 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0953,283,830 - 53,291,704 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0951,565,699 - 51,573,573 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd950,931,538 - 50,939,412 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive946,706,934 - 46,714,808 (+)NCBILyon_Normotensive
Lyon_Hypertensive946,842,291 - 46,850,165 (+)NCBILyon_Hypertensive
F344_StmMcwi948,767,656 - 48,775,529 (+)NCBIF344_StmMcwi
Rnor_6.0944,024,994 - 44,032,896 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl944,025,020 - 44,032,888 (+)Ensemblrn6Rnor6.0
Rnor_5.0943,726,196 - 43,734,124 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4936,375,661 - 36,383,535 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera937,419,271 - 37,427,145 (+)NCBICelera
RGSC_v3.1936,377,074 - 36,384,946 (+)NCBI
RH 3.4 Map9365.9RGD
Cytogenetic Map9q21NCBI
Unc50
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554705,051,475 - 5,059,890 (+)Ensembl
ChiLan1.0NW_0049554705,050,982 - 5,059,890 (+)NCBIChiLan1.0ChiLan1.0
UNC50
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21229,826,095 - 29,835,997 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A29,828,976 - 29,838,759 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A100,693,433 - 100,703,371 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A99,516,848 - 99,526,785 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A99,516,857 - 99,526,785 (+)EnsemblpanPan2panpan1.1
UNC50
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11044,057,617 - 44,073,153 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1044,057,775 - 44,073,074 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1043,980,524 - 43,995,508 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01044,931,041 - 44,946,061 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1044,931,025 - 44,945,866 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11044,641,462 - 44,656,444 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01044,932,398 - 44,947,410 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01045,108,149 - 45,123,136 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Unc50
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629284,449,010 - 84,457,064 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367441,701,632 - 1,709,826 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367441,701,988 - 1,710,007 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC50
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1142,322,167 - 2,333,518 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl142,322,206 - 2,333,495 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041169,842,761 - 169,858,697 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc50
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247493,645,869 - 3,655,666 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247493,646,365 - 3,655,666 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Unc50
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14113,633,195 - 113,641,019 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in UNC50
177 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000023132   ⟹   ENSSSCP00000025105
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl355,667,826 - 55,676,978 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000064589   ⟹   ENSSSCP00000052289
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl355,667,826 - 55,676,912 (-)Ensembl
RefSeq Acc Id: XM_003124908   ⟹   XP_003124956
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1355,667,821 - 55,676,993 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003124909   ⟹   XP_003124957
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1355,667,821 - 55,676,981 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013987864   ⟹   XP_013843318
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1355,667,821 - 55,676,995 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013987865   ⟹   XP_013843319
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1355,667,821 - 55,676,981 (-)NCBI
Sequence:
RefSeq Acc Id: XP_013843318   ⟸   XM_013987864
- Peptide Label: isoform X1
- UniProtKB: A0A8D0HYD8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003124956   ⟸   XM_003124908
- Peptide Label: isoform X2
- UniProtKB: I3LLY5 (UniProtKB/TrEMBL),   A0A8D1I160 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003124957   ⟸   XM_003124909
- Peptide Label: isoform X2
- UniProtKB: I3LLY5 (UniProtKB/TrEMBL),   A0A8D1I160 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013843319   ⟸   XM_013987865
- Peptide Label: isoform X1
- UniProtKB: A0A8D0HYD8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000052289   ⟸   ENSSSCT00000064589
Ensembl Acc Id: ENSSSCP00000025105   ⟸   ENSSSCT00000023132


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025010 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015067410 UniProtKB/TrEMBL
  ENSSSCG00025030887 UniProtKB/TrEMBL
  ENSSSCG00030004766 UniProtKB/TrEMBL
  ENSSSCG00035056870 UniProtKB/TrEMBL
  ENSSSCG00040000976 UniProtKB/TrEMBL
  ENSSSCG00045022337 UniProtKB/TrEMBL
  ENSSSCG00050012333 UniProtKB/TrEMBL
  ENSSSCG00055012220 UniProtKB/TrEMBL
  ENSSSCG00060068638 UniProtKB/TrEMBL
  ENSSSCG00065061533 UniProtKB/TrEMBL
  ENSSSCG00070028482 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000023132 ENTREZGENE
  ENSSSCT00000023132.4 UniProtKB/TrEMBL
  ENSSSCT00015090403.1 UniProtKB/TrEMBL
  ENSSSCT00015090523.1 UniProtKB/TrEMBL
  ENSSSCT00025042018.1 UniProtKB/TrEMBL
  ENSSSCT00025042116.1 UniProtKB/TrEMBL
  ENSSSCT00030006422.1 UniProtKB/TrEMBL
  ENSSSCT00030006426.1 UniProtKB/TrEMBL
  ENSSSCT00035076023.1 UniProtKB/TrEMBL
  ENSSSCT00035076027.1 UniProtKB/TrEMBL
  ENSSSCT00040001151.1 UniProtKB/TrEMBL
  ENSSSCT00040001198.1 UniProtKB/TrEMBL
  ENSSSCT00045038159.1 UniProtKB/TrEMBL
  ENSSSCT00045038199.1 UniProtKB/TrEMBL
  ENSSSCT00050016637.1 UniProtKB/TrEMBL
  ENSSSCT00050016649.1 UniProtKB/TrEMBL
  ENSSSCT00055023953.1 UniProtKB/TrEMBL
  ENSSSCT00055023998.1 UniProtKB/TrEMBL
  ENSSSCT00060093716.1 UniProtKB/TrEMBL
  ENSSSCT00060093734.1 UniProtKB/TrEMBL
  ENSSSCT00065084338.1 UniProtKB/TrEMBL
  ENSSSCT00065084344.1 UniProtKB/TrEMBL
  ENSSSCT00070057110.1 UniProtKB/TrEMBL
  ENSSSCT00070057114.1 UniProtKB/TrEMBL
  ENSSSCT00070057117.1 UniProtKB/TrEMBL
InterPro UNC-50 UniProtKB/TrEMBL
KEGG Report ssc:100524249 UniProtKB/TrEMBL
NCBI Gene UNC50 ENTREZGENE
PANTHER PROTEIN UNC-50 HOMOLOG UniProtKB/TrEMBL
  PTHR12841 UniProtKB/TrEMBL
Pfam UNC-50 UniProtKB/TrEMBL
UniProt A0A8D0HYD8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0UA50_PIG UniProtKB/TrEMBL
  A0A8D1I160 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1JV13_PIG UniProtKB/TrEMBL
  I3LLY5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:94706 ENTREZGENE