Kat14 (lysine acetyltransferase 14)

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Gene: Kat14 (lysine acetyltransferase 14) Rattus norvegicus

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Symbol:

Kat14

Name:

lysine acetyltransferase 14

RGD ID:

1309538

Description:

Predicted to enable histone acetyltransferase activity. Predicted to be involved in several processes, including negative regulation of transcription by RNA polymerase II; regulation of embryonic development; and regulation of tubulin deacetylation. Predicted to act upstream of or within G2/M transition of mitotic cell cycle. Predicted to be located in nucleus. Predicted to be part of ATAC complex. Orthologous to human KAT14 (lysine acetyltransferase 14); PARTICIPATES IN RNA polymerase II transcription initiation pathway; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 1-naphthyl isothiocyanate; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CSRP2 binding protein; Csrp2bp; cysteine and glycine-rich protein 2 binding protein; cysteine-rich protein 2-binding protein; LOC362224

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KAT14 (lysine acetyltransferase 14)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Kat14 (lysine acetyltransferase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Kat14 (lysine acetyltransferase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KAT14 (lysine acetyltransferase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KAT14 (lysine acetyltransferase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kat14 (lysine acetyltransferase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KAT14 (lysine acetyltransferase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KAT14 (lysine acetyltransferase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Kat14 (lysine acetyltransferase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	KAT14 (lysine acetyltransferase 14)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Kat14 (lysine acetyltransferase 14)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Atac2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	kat14	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ribc1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	kat14	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	152,194,560 - 152,235,048 (+)	NCBI		GRCr8
mRatBN7.2	3	131,736,430 - 131,781,732 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	131,736,549 - 131,781,706 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	135,665,315 - 135,705,967 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	144,249,402 - 144,290,049 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	141,952,588 - 141,993,238 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	138,508,899 - 138,549,437 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	138,504,214 - 138,549,437 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	144,939,294 - 144,979,526 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	132,906,338 - 132,946,872 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	132,812,166 - 132,851,576 (+)	NCBI
Celera	3	130,635,918 - 130,676,280 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital dyserythropoietic anemia type II (ISO)

Developmental Disabilities (ISO)

familial hyperinsulinemic hypoglycemia 1 (ISO)

mitochondrial complex IV deficiency nuclear type 19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1,3,5-trinitro-1,3,5-triazinane (EXP)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

amphetamine (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

C60 fullerene (EXP)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

chrysene (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

genistein (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

indometacin (ISO)

iron dichloride (ISO)

methylmercury chloride (ISO)

nickel sulfate (ISO)

ochratoxin A (EXP,ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

pentachlorophenol (ISO)

perfluorohexanesulfonic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

rac-lactic acid (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

succimer (ISO)

temozolomide (ISO)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

chromatin remodeling (IEA)

G2/M transition of mitotic cell cycle (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

regulation of cell cycle (ISO)

regulation of cell division (ISO)

regulation of DNA-templated transcription (ISO)

regulation of embryonic development (ISO)

regulation of transcription by RNA polymerase II (ISO)

regulation of tubulin deacetylation (ISO)

Cellular Component

ATAC complex (ISO)

nucleus (ISO)

Molecular Function

histone acetyltransferase activity (IBA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase II transcription initiation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation
6.	ATAC-king the complexity of SAGA during evolution.	Spedale G, etal., Genes Dev. 2012 Mar 15;26(6):527-41. doi: 10.1101/gad.184705.111.

Additional References at PubMed

PMID:10924333	PMID:18838386	PMID:19103755	PMID:20508642	PMID:20562830

Genomics

Comparative Map Data

Kat14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	152,194,560 - 152,235,048 (+)	NCBI		GRCr8
mRatBN7.2	3	131,736,430 - 131,781,732 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	131,736,549 - 131,781,706 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	135,665,315 - 135,705,967 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	144,249,402 - 144,290,049 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	141,952,588 - 141,993,238 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	138,508,899 - 138,549,437 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	138,504,214 - 138,549,437 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	144,939,294 - 144,979,526 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	132,906,338 - 132,946,872 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	132,812,166 - 132,851,576 (+)	NCBI
Celera	3	130,635,918 - 130,676,280 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

KAT14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	18,137,153 - 18,188,035 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	18,137,228 - 18,188,387 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	18,117,797 - 18,168,679 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	18,066,527 - 18,117,016 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	18,073,742 - 18,117,016	NCBI
Celera	20	18,197,589 - 18,243,750 (+)	NCBI		Celera
Cytogenetic Map	20	p11.23	NCBI
HuRef	20	18,085,681 - 18,131,828 (+)	NCBI		HuRef
CHM1_1	20	18,122,862 - 18,169,027 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	18,188,023 - 18,238,897 (+)	NCBI		T2T-CHM13v2.0

Kat14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	144,210,952 - 144,249,595 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	144,210,903 - 144,249,596 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	144,369,032 - 144,407,675 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	144,368,983 - 144,407,676 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	144,194,768 - 144,233,411 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	144,060,476 - 144,099,074 (+)	NCBI		MGSCv36	mm8
Celera	2	156,152,239 - 156,165,943 (+)	NCBI		Celera
Cytogenetic Map	2	G1	NCBI
cM Map	2	71.01	NCBI

Kat14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	26,871,668 - 26,898,035 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	26,872,095 - 26,895,009 (+)	NCBI	ChiLan1.0	ChiLan1.0

KAT14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	19,036,786 - 19,082,158 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	19,033,624 - 19,078,999 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	18,106,400 - 18,152,231 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	18,082,402 - 18,128,470 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	18,082,402 - 18,128,470 (+)	Ensembl	panpan1.1		panPan2

KAT14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	4,933,066 - 4,968,473 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	4,933,069 - 4,968,216 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	4,863,615 - 4,898,759 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	5,340,851 - 5,376,000 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	5,340,853 - 5,379,359 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	4,940,702 - 4,975,622 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	5,047,857 - 5,082,770 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	5,324,172 - 5,359,164 (-)	NCBI		UU_Cfam_GSD_1.0

Kat14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	153,561,888 - 153,599,859 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936485	1,955,924 - 2,031,650 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936485	1,992,894 - 2,031,632 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KAT14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	26,485,157 - 26,521,525 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	26,484,957 - 26,521,532 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	29,973,704 - 30,010,168 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KAT14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	47,207,964 - 47,253,813 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	47,203,676 - 47,254,318 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666078	1,929,534 - 1,979,060 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kat14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	19,043,628 - 19,077,450 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	19,044,033 - 19,077,163 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Kat14
198 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	142
Count of miRNA genes:	104
Interacting mature miRNAs:	125
Transcripts:	ENSRNOT00000009437
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
1598877	Bp285	Blood pressure QTL 285	1.5	0.03	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	120538241	165538241	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	130656562	169034231	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	112681431	157681431	Rat
1300173	Rf11	Renal function QTL 11	3.38		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	121056165	145956249	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	131635904	169034231	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	122438700	167438700	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	97084464	142084464	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	127162703	168026850	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
1358204	Insglur1	Insulin/glucose ratio QTL 1	3.8		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	3	115638168	135181505	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	118839124	163839124	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	107693393	152693393	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	121056165	157309487	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	130193298	161695983	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	130656562	169034231	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	112287552	135181505	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	124122556	169034231	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat

Markers in Region

RH130024

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	131,741,572 - 131,741,758 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	138,509,271 - 138,509,456	NCBI	Rnor6.0
Rnor_5.0	3	144,939,666 - 144,939,851	UniSTS	Rnor5.0
RGSC_v3.4	3	132,906,710 - 132,906,895	UniSTS	RGSC3.4
Celera	3	130,636,290 - 130,636,475	UniSTS
RH 3.4 Map	3	1180.5	UniSTS
Cytogenetic Map	3	q41	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105474	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000009437 ⟹ ENSRNOP00000009437

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	131,736,549 - 131,781,706 (+)	Ensembl
Rnor_6.0 Ensembl	3	138,508,899 - 138,549,437 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000091529 ⟹ ENSRNOP00000073893

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	131,741,460 - 131,781,706 (+)	Ensembl
Rnor_6.0 Ensembl	3	138,504,214 - 138,548,765 (+)	Ensembl

RefSeq Acc Id:

NM_001191855 ⟹ NP_001178784

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	152,194,560 - 152,235,048 (+)	NCBI
mRatBN7.2	3	131,741,201 - 131,781,704 (+)	NCBI
Rnor_6.0	3	138,508,899 - 138,549,437 (+)	NCBI
Rnor_5.0	3	144,939,294 - 144,979,526 (+)	NCBI
Celera	3	130,635,918 - 130,676,280 (+)	NCBI

Sequence:

show sequence

GAGAAGCCGATGGGGCAGCGCTGAGTTGGTGTGTGTAACTGTGGGTGCGGTGTGTGGTAGAGAA
TAGCTAGTGAGAGCTGCCCCCAAAATCACTATCCAGTTACACTTCATTAACTGAAGGACAGTGG
TCCTGTCTTCTGAATTGCTTCTTTTAAGAGTCTGTCGTGTGTGGAGAGAGTACTTGGGGGCAAA
TGCTCTTCTGAAGGTCTGTCTGGGGGATCCCTGCAACAGTGCCTGTCAGCTTAGGAGTGCAGGG
GCGATGGATAGTAGCATCCACCTGAGTGGGCTCCTAAGTCGGCATGATGATGAAGCCACGAGAA
CGTCTACCTCGGAAGGGCTGGAGGAAGGTGAGGTGGAGGGAGAGACTCTCCTAATTGTGGAATC
AGAGGATCAGGCATCAGTGGACTTATCTCACGACCAGAGTGGGGATTCCCTCAACAGCGATGAA
GGAGATATATCATGGATGGAGGAGCAGCTGTCTTACTTCTGTGACAAGTGCCAAAAGTGGATCC
CAGCCAGTCAGCTGAGGGAACAGCTCAGTTACCTTAAGGGCGATAACTTTTTCAGGTTTACTTG
TGCCGATTGCTCGGCAGACGGCAAGGAGCAGTCCGAGAGGCTGAAGCTGACATGGCAGCAAGTG
GTCATGCTGGCTATGTACAACTTGTCTCTGGAAGGAAGTGGACGTCAAGGCTACTTCCGGTGGA
AAGAAGATATCTGTGCTTTTATTGAGAAACATTGGACTTTTTTACTAGGAAATAGGAAAAAGAC
TTCGACGTGGTGGAGCACAGTAGCAGGTTGCCTCAGCGTGGGAAGTCCTGTTTATTTCCGTTCA
GGTGCTCAGGAATTTGGAGAGCCTGGATGGTGGAAACTTGTTCATAACAGACCCCCAACAATGA
GACCAGAGGGAGAGAAGCTGTCTGCCTCCACTTTGAAAGTGAAAGCTTCAAAACCAACACTGGA
TCCCATCATTACCGTTGAAGGACTCAGAAAACGAGCAAGCCGGAATCCTGTGGAATCAGCCATG
GAATTGAAAGAGAAGCGGTCTCGAACACAGGAAGCTAAAGACATCAGAAGAGCACAGAAAGAAG
CAGCCGGCCTCCTTGACAGAAGCACCTCTTCTACCCCTGTCAAGTTCATAAGCCGAGGCCGGAG
GCCGGATATGATTTTGGAGAAAGGAGAAGTGATTGACTTTTCATCCCTGAGCTCCTCGGACCGT
ACCCCCCTCACAAGCCCCTCTCCTTCTCCCTCTCTGGATTTCTCTGCCCCAGGGACACCAGCGT
CACATTCTGCCACGCCTAGCTTGCTCTCTGAAGCAGACCTCATCCCAGACGTGATGCCACCCCA
AGCTCTATTTCATGATGATGATGAGCTGGAAGGAGATGGAGTCATAGACCCAGGGATGGAGTAC
ATCCCACCCCCAGCTGGGTCAGCTTCTGGGCTGATGGGGAGCAGAAAGAAGGTCAGAGCTGCAG
AGCAGATAAAACAGGAAGTCGACAGCGAGGAGGAGAAGCCAGACAGGATGGATGGAGATAGCGA
AGACACAGATTCAAACACTTCTTTGCACACTAGAGCTCGAGAAAAGAGGAAGCCACCCCTGGAG
AAGGACACGAAGCCCAAGGGGCCCAGGTATACGCCTGTGAGCATCTATGAGGAGAAGCTGCTGC
TCAAGAGGCTGGAGGCATGCCCTGGTGCCGTGGCCATGACTCCAGAAGCCCGGAGGCTGAAACG
GAAGCTGATCGTCCGGCAAGCAAAAAGGGATCGGGGCTTACCACTGTTTGACTTGGACGAGGTT
GTGAACGCAGCACTTCTGTTAGTGGATGGGATTTATGGAGCCAAAGATGGAGGAGCTTCCCGGC
TTCCAGCTGGACAAGCTACATACCGGACCACCTGCCAGGACTTCAGGATCCTTGACCGGTACCA
GACTGCCTTACCAGCCAGGAAAGGATTCCGGCACCAGACCACCAGATTTTTGTATCGTCTGGTG
GGATCAGAAGATCTGGCTGTGGACCAAAGTATTGTCAGCCCTTACACTTCTCGGATCTTGAAAC
CTTATATCAGGCGTGATTATGAGACAAAGCCACCCAAACTACAGCTGCTGTCCCAGATTCGCTC
CCACCTGCACAAGAGTGACCCTCACTGGACACCTGAACCTGATGCACCTCTCGATTACTGCTAT
GTCCGACCAAATCACATCCCAACGATCAACTCCATGTGTCAGGAATTTTTCTGGCCTGGCATTG
ACCTGTCTGAGTGTCTGCAGTATCCAGACTTCAGTGTCGTAGTCCTTTATAAAAAAGTCATTGT
TGCCTTTGGCTTCATGGTTCCCGATGTGAAGTACAACGAAGCTTACATTTCATTTCTGCTTGTT
CATCCCGAGTGGAGGAGAGCAGGGATTGCCACGTTCATGATCTATCATCTGATTCAGACGTGCA
TGGGCAAGGATGTGACTCTTCACGTCTCGGCGAGCAACCCTGCCATGCTGCTGTACCAGAAGTT
TGGCTTCAAGACAGAGGAGTATGTTTTGGATTTTTATGATAAGTATTACCCACTGGAGAGTACA
GAGTGTAAACATGCATTCTTCCTGAGGCTCCGACGCTGAGGTGAACTCAGTTCTTCCCAGCAAA
CAGCAGATGCTGTCAGAGAGTGGCCTCAGAAGTCGTGCAGGCCCTTCTCCTCGAAGTGGGCCCT
GGCCTCCTGTGAGTAATGGCCTCCACAGGGTCCAGCTGGGTGAGTGAAGCCATGTGCAGAGGTA
CAAGTGGCTGTTCAATCCAGAAACCATCCAGCAGGCCCTGCGTGGCCTTCCAGCAGTATCTTGG
ACTCCACTGTGGACCAGAACCAAGTGACTCTGCCATTCTTTTTCCACACAATGAGTGGGCACAA
AAGAGCTTCTGAGCTGAAGCATTTGAGAATGGGCCTGCTCCTCCTATGTTAGAGCTCAGGAAGT
ATGAAAGATGTTAAAGACTGCCAGGGCCCTCACTGTCCTGGGCCGAGAGGTTATGAGGTGTCAG
GAATGACTCCAACCCTGTCTCAGCCTGTGCTGTGCTGTCATCGAACCCCAGAGGATTCATGGGG
CACTGAAGTCCTTTTGTCTCTTACTGACTTTCGTCCTGGTCAGGAAAAAGATACTCGGTGTCTG
TTTCCAGACTGCTGCTGCTTTACTTATCTACCTGTCAGCACCCCTTGCAGGGACATTGACCTGG
TACAAGAAGTTTACTCTTGGCATGGCCTGGAAAGTAGCCCGAGAGGAACGGTTGAGCTTGATAC
ATTAGATGCCTTCCCAGGCCCTTCTCATGCTCAGGACAGTTGCACCACAGAAGTGGAGGTGTGG
AATGGCGCAGGCAGGCCTGGGCGCCCTGTCCACCTCATGAAGCTGCTTCCTGTGTTGCACATGT
TGGAGTTGGACTACAGGTATCTAAGTGCATTCCAAAAGCATCAGATATCTCCAATAAAAATCCT
TACCATACAACAA

hide sequence

RefSeq Acc Id:

XM_039105474 ⟹ XP_038961402

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	152,197,217 - 152,235,048 (+)	NCBI
mRatBN7.2	3	131,743,858 - 131,781,732 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178784	(Get FASTA)	NCBI Sequence Viewer
	XP_038961402	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000009437.5
	ENSRNOP00000073893.2

RefSeq Acc Id:

NP_001178784 ⟸ NM_001191855

- UniProtKB:

D3ZSX8 (UniProtKB/TrEMBL), A0A0G2K6P6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDSSIHLSGLLSRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEG
DISWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCADCSADGKEQSERLKLTWQQVV
MLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPVYFRSG
AQEFGEPGWWKLVHNRPPTMRPEGEKLSASTLKVKASKPTLDPIITVEGLRKRASRNPVESAME
LKEKRSRTQEAKDIRRAQKEAAGLLDRSTSSTPVKFISRGRRPDMILEKGEVIDFSSLSSSDRT
PLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDELEGDGVIDPGMEYI
PPPAGSASGLMGSRKKVRAAEQIKQEVDSEEEKPDRMDGDSEDTDSNTSLHTRAREKRKPPLEK
DTKPKGPRYTPVSIYEEKLLLKRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDEVV
NAALLLVDGIYGAKDGGASRLPAGQATYRTTCQDFRILDRYQTALPARKGFRHQTTRFLYRLVG
SEDLAVDQSIVSPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHKSDPHWTPEPDAPLDYCYV
RPNHIPTINSMCQEFFWPGIDLSECLQYPDFSVVVLYKKVIVAFGFMVPDVKYNEAYISFLLVH
PEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTE
CKHAFFLRLRR

hide sequence

Ensembl Acc Id:

ENSRNOP00000073893 ⟸ ENSRNOT00000091529

Ensembl Acc Id:

ENSRNOP00000009437 ⟸ ENSRNOT00000009437

RefSeq Acc Id:	XP_038961402 ⟸ XM_039105474
- Peptide Label:	isoform X1

Protein Domains

N-acetyltransferase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZSX8-F1-model_v2	AlphaFold	D3ZSX8	1-779	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692492

Promoter ID:

EPDNEW_R3006

Type:

multiple initiation site

Name:

Kat14_1

Description:

lysine acetyltransferase 14

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	138,504,224 - 138,504,284	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309538	AgrOrtholog
BioCyc Gene	G2FUF-47601	BioCyc
Ensembl Genes	ENSRNOG00000007160	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000009437.7	UniProtKB/TrEMBL
	ENSRNOT00000091529.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.630.30	UniProtKB/TrEMBL
	3.90.980.20	UniProtKB/TrEMBL
InterPro	AcTrfase_GCN5-related	UniProtKB/TrEMBL
	Acyl_CoA_acyltransferase	UniProtKB/TrEMBL
KEGG Report	rno:362224	UniProtKB/TrEMBL
NCBI Gene	362224	ENTREZGENE
PANTHER	CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN	UniProtKB/TrEMBL
	CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN	UniProtKB/TrEMBL
Pfam	Acetyltransf_1	UniProtKB/TrEMBL
PhenoGen	Kat14	PhenoGen
PROSITE	GNAT	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000007160	RatGTEx
Superfamily-SCOP	Acyl_CoA_acyltransferase	UniProtKB/TrEMBL
UniProt	A0A0G2K6P6	ENTREZGENE, UniProtKB/TrEMBL
	D3ZSX8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-05-04	Kat14	lysine acetyltransferase 14	Csrp2bp	CSRP2 binding protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-26	Csrp2bp	CSRP2 binding protein	Csrp2bp	cysteine and glycine-rich protein 2 binding protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Csrp2bp	cysteine and glycine-rich protein 2 binding protein	Csrp2bp_predicted	cysteine and glycine-rich protein 2 binding protein (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Csrp2bp_predicted	cysteine and glycine-rich protein 2 binding protein (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

RGD Manual Annotations