Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dipk1a | Rat | (+)-catechin | multiple interactions | ISO | DIPK1A (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of DIPK1A mRNA | CTD | PMID:24763279 | Dipk1a | Rat | 1,2-dichloroethane | decreases expression | ISO | Dipk1a (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of FAM69A mRNA | CTD | PMID:28960355 | Dipk1a | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Dipk1a (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of FAM69A mRNA | CTD | PMID:22206623 | Dipk1a | Rat | 17beta-estradiol | multiple interactions | ISO | DIPK1A (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of DIPK1A mRNA | CTD | PMID:19619570 | Dipk1a | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of FAM69A mRNA | CTD | PMID:32145629 | Dipk1a | Rat | 17beta-estradiol | increases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Estradiol results in increased expression of DIPK1A mRNA | CTD | PMID:19619570 | Dipk1a | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of FAM69A mRNA | CTD | PMID:29581250 | Dipk1a | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19095052 | Dipk1a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | DIPK1A (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of DIPK1A mRNA | CTD | PMID:19619570 | Dipk1a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Dipk1a (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of DIPK1A mRNA | CTD | PMID:25975270 | Dipk1a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DIPK1A mRNA | CTD | PMID:22298810 and PMID:22574217 | Dipk1a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DIPK1A mRNA | CTD | PMID:19619570 and PMID:19692669 | Dipk1a | Rat | 3,3',4,4',5-pentachlorobiphenyl | increases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | 3 more ... | CTD | PMID:19692669 | Dipk1a | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of DIPK1A mRNA | CTD | PMID:28522335 | Dipk1a | Rat | aflatoxin B1 | decreases methylation | ISO | DIPK1A (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of DIPK1A gene | CTD | PMID:27153756 | Dipk1a | Rat | aflatoxin B1 | decreases expression | ISO | Dipk1a (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of DIPK1A mRNA | CTD | PMID:19770486 | Dipk1a | Rat | aflatoxin M1 | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of DIPK1A mRNA | CTD | PMID:30928695 | Dipk1a | Rat | all-trans-retinoic acid | increases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Tretinoin results in increased expression of DIPK1A mRNA | CTD | PMID:21934132 | Dipk1a | Rat | all-trans-retinoic acid | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of FAM69A mRNA | CTD | PMID:33167477 | Dipk1a | Rat | antirheumatic drug | increases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of DIPK1A mRNA | CTD | PMID:24449571 | Dipk1a | Rat | aristolochic acid A | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of FAM69A mRNA | CTD | PMID:33212167 | Dipk1a | Rat | benzo[a]pyrene | increases expression | ISO | Dipk1a (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of FAM69A mRNA | CTD | PMID:35678645 | Dipk1a | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DIPK1A mRNA and bisphenol A results in increased expression of FAM69A mRNA | CTD | PMID:30816183 more ... | Dipk1a | Rat | bisphenol A | increases expression | ISO | Dipk1a (Mus musculus) | 6480464 | bisphenol A results in increased expression of DIPK1A mRNA | CTD | PMID:33221593 more ... | Dipk1a | Rat | bisphenol A | decreases expression | ISO | Dipk1a (Mus musculus) | 6480464 | bisphenol A results in decreased expression of DIPK1A mRNA | CTD | PMID:29161229 | Dipk1a | Rat | bisphenol F | increases methylation | ISO | DIPK1A (Homo sapiens) | 6480464 | bisphenol F results in increased methylation of DIPK1A gene | CTD | PMID:31601247 | Dipk1a | Rat | carbon nanotube | decreases expression | ISO | Dipk1a (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | Dipk1a | Rat | chlordecone | multiple interactions | ISO | Dipk1a (Mus musculus) | 6480464 | Chlordecone promotes the reaction [Biomarkers metabolite binds to FAM69A gene] | CTD | PMID:31084621 | Dipk1a | Rat | chlorpyrifos | increases expression | ISO | Dipk1a (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of DIPK1A mRNA | CTD | PMID:37019170 | Dipk1a | Rat | diuron | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Diuron results in decreased expression of DIPK1A mRNA | CTD | PMID:35967413 | Dipk1a | Rat | dorsomorphin | multiple interactions | ISO | DIPK1A (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DIPK1A mRNA | CTD | PMID:27188386 | Dipk1a | Rat | doxorubicin | affects response to substance | ISO | DIPK1A (Homo sapiens) | 6480464 | DIPK1A protein affects the susceptibility to Doxorubicin | CTD | PMID:16217747 | Dipk1a | Rat | doxorubicin | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of DIPK1A mRNA | CTD | PMID:29803840 | Dipk1a | Rat | entinostat | increases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | entinostat results in increased expression of DIPK1A mRNA | CTD | PMID:27188386 | Dipk1a | Rat | epoxiconazole | increases expression | ISO | Dipk1a (Mus musculus) | 6480464 | epoxiconazole results in increased expression of DIPK1A mRNA | CTD | PMID:35436446 | Dipk1a | Rat | ethyl methanesulfonate | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of DIPK1A mRNA | CTD | PMID:23649840 | Dipk1a | Rat | fluoranthene | multiple interactions | ISO | Dipk1a (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of DIPK1A mRNA | CTD | PMID:28329830 | Dipk1a | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of DIPK1A mRNA | CTD | PMID:24793618 | Dipk1a | Rat | folic acid | decreases expression | ISO | Dipk1a (Mus musculus) | 6480464 | Folic Acid results in decreased expression of FAM69A mRNA | CTD | PMID:25629700 | Dipk1a | Rat | formaldehyde | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of DIPK1A mRNA | CTD | PMID:23649840 | Dipk1a | Rat | furan | decreases expression | ISO | Dipk1a (Mus musculus) | 6480464 | furan results in decreased expression of DIPK1A mRNA | CTD | PMID:24183702 | Dipk1a | Rat | ketamine | increases expression | EXP | | 6480464 | Ketamine results in increased expression of DIPK1A mRNA | CTD | PMID:20080153 | Dipk1a | Rat | lead(0) | affects expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Lead affects the expression of DIPK1A mRNA | CTD | PMID:28903495 | Dipk1a | Rat | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of DIPK1A mRNA | CTD | PMID:19564919 | Dipk1a | Rat | methyl methanesulfonate | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of DIPK1A mRNA | CTD | PMID:23649840 | Dipk1a | Rat | methylisothiazolinone | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in decreased expression of DIPK1A mRNA | CTD | PMID:31629900 | Dipk1a | Rat | methylmercury chloride | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of DIPK1A mRNA | CTD | PMID:28001369 | Dipk1a | Rat | N-nitrosodiethylamine | decreases expression | ISO | Dipk1a (Mus musculus) | 6480464 | Diethylnitrosamine results in decreased expression of DIPK1A mRNA | CTD | PMID:24535843 | Dipk1a | Rat | ochratoxin A | increases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | ochratoxin A results in increased expression of FAM69A mRNA | CTD | PMID:30559759 | Dipk1a | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of FAM69A mRNA | CTD | PMID:33387578 | Dipk1a | Rat | pentachlorophenol | increases expression | ISO | Dipk1a (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of DIPK1A mRNA | CTD | PMID:23892564 | Dipk1a | Rat | perfluorooctanoic acid | increases expression | ISO | Dipk1a (Mus musculus) | 6480464 | perfluorooctanoic acid results in increased expression of FAM69A mRNA | CTD | PMID:35678645 | Dipk1a | Rat | phenobarbital | affects expression | ISO | Dipk1a (Mus musculus) | 6480464 | Phenobarbital affects the expression of DIPK1A mRNA | CTD | PMID:23091169 | Dipk1a | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of FAM69A mRNA | CTD | PMID:28374803 | Dipk1a | Rat | SB 431542 | multiple interactions | ISO | DIPK1A (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DIPK1A mRNA | CTD | PMID:27188386 | Dipk1a | Rat | sodium arsenate | increases expression | ISO | Dipk1a (Mus musculus) | 6480464 | sodium arsenate results in increased expression of DIPK1A mRNA | CTD | PMID:21795629 | Dipk1a | Rat | sunitinib | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of DIPK1A mRNA | CTD | PMID:31533062 | Dipk1a | Rat | tebufenpyrad | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of DIPK1A mRNA | CTD | PMID:33512557 | Dipk1a | Rat | tetrachloroethene | increases expression | ISO | Dipk1a (Mus musculus) | 6480464 | Tetrachloroethylene results in increased expression of DIPK1A mRNA | CTD | PMID:28973375 | Dipk1a | Rat | tetrachloromethane | decreases expression | ISO | Dipk1a (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of DIPK1A mRNA | CTD | PMID:31919559 | Dipk1a | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of DIPK1A mRNA | CTD | PMID:34492290 | Dipk1a | Rat | titanium dioxide | decreases expression | ISO | Dipk1a (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of FAM69A mRNA | CTD | PMID:29264374 | Dipk1a | Rat | trichostatin A | decreases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of DIPK1A mRNA | CTD | PMID:26272509 | Dipk1a | Rat | trichostatin A | multiple interactions | ISO | DIPK1A (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DIPK1A mRNA | CTD | PMID:27188386 | Dipk1a | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of FAM69A mRNA | CTD | PMID:30589522 | Dipk1a | Rat | triphenyl phosphate | affects expression | ISO | DIPK1A (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of FAM69A mRNA | CTD | PMID:37042841 | Dipk1a | Rat | tungsten | increases expression | ISO | Dipk1a (Mus musculus) | 6480464 | Tungsten results in increased expression of FAM69A mRNA | CTD | PMID:30912803 | Dipk1a | Rat | valproic acid | affects expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DIPK1A mRNA | CTD | PMID:25979313 | Dipk1a | Rat | valproic acid | increases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of DIPK1A mRNA | CTD | PMID:23179753 and PMID:27188386 | Dipk1a | Rat | valproic acid | decreases methylation | ISO | DIPK1A (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of DIPK1A gene | CTD | PMID:29154799 | Dipk1a | Rat | vincaleukoblastine | affects response to substance | ISO | DIPK1A (Homo sapiens) | 6480464 | DIPK1A protein affects the susceptibility to Vinblastine | CTD | PMID:16217747 | Dipk1a | Rat | vorinostat | increases expression | ISO | DIPK1A (Homo sapiens) | 6480464 | vorinostat results in increased expression of DIPK1A mRNA | CTD | PMID:22083351 and PMID:27188386 | |