Col4a2 (collagen type IV alpha 2 chain) - Rat Genome Database

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Gene: Col4a2 (collagen type IV alpha 2 chain) Rattus norvegicus
Analyze
Symbol: Col4a2
Name: collagen type IV alpha 2 chain
RGD ID: 1308085
Description: Predicted to enable molecular adaptor activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in response to activity. Predicted to be located in basement membrane. Predicted to be part of collagen type IV trimer. Predicted to be active in extracellular matrix. Human ortholog(s) of this gene implicated in atherosclerosis; brain small vessel disease 2; porencephaly; and uterine fibroid. Orthologous to human COL4A2 (collagen type IV alpha 2 chain); PARTICIPATES IN cell-extracellular matrix signaling pathway; Entamoebiasis pathway; small cell lung carcinoma pathway; INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha-2 collagen type IV; collagen alpha-2(IV) chain; collagen, type IV, alpha 2; LOC306628; procollagen, type IV, alpha 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81684,749,672 - 84,885,520 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1684,749,672 - 84,885,520 (-)EnsemblGRCr8
mRatBN7.21678,047,591 - 78,183,360 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1678,047,602 - 78,183,839 (-)EnsemblmRatBN7.2
Rnor_6.01683,386,388 - 83,522,169 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1683,387,364 - 83,438,561 (-)Ensemblrn6Rnor6.0
Rnor_5.01682,852,230 - 82,987,790 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41682,899,206 - 83,045,102 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1675,846,004 - 75,981,238 (-)NCBICelera
RGSC_v3.11682,871,435 - 83,006,872 (-)NCBI
Cytogenetic Map16q12.5NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-methylcholine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
8'-apo-beta,psi-caroten-8'-al  (ISO)
9-cis-retinoic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-4-oxoretinol  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
antimycin A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
beta-carotene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chromium(6+)  (ISO)
ciprofibrate  (ISO)
cisplatin  (ISO)
citalopram  (EXP)
clobetasol  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dibenz[a,h]anthracene  (ISO)
dicrotophos  (ISO)
dimethylarsinous acid  (ISO)
dimethylselenide  (ISO)
dioxygen  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
erianin  (ISO)
escitalopram  (EXP)
ethanol  (ISO)
folpet  (ISO)
glucose  (ISO)
hydroxyl  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methidathion  (ISO)
methimazole  (EXP)
mitomycin C  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
nickel subsulfide  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
phenethyl isothiocyanate  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
streptozocin  (ISO)
sulfadimethoxine  (EXP)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Structure of the rat collagen IV promoter. Grande JP, etal., Biochim Biophys Acta. 1996 Nov 11;1309(1-2):85-8.
4. A mutation in COL4A2 causes autosomal dominant porencephaly with cataracts. Ha TT, etal., Am J Med Genet A. 2016 Apr;170A(4):1059-63. doi: 10.1002/ajmg.a.37527. Epub 2015 Dec 28.
5. Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons. Hixson JE, etal., Sci Rep. 2017 Jun 22;7(1):4091. doi: 10.1038/s41598-017-04433-x.
6. Effects of aging on basement membrane of the soleus muscle during recovery following disuse atrophy in rats. Kanazawa Y, etal., Exp Gerontol. 2017 Nov;98:153-161. doi: 10.1016/j.exger.2017.08.014. Epub 2017 Aug 10.
7. Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas. Maekawa R, etal., PLoS One. 2013 Jun 20;8(6):e66632. doi: 10.1371/journal.pone.0066632. Print 2013.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. COL4A2 is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls. Rannikmäe K, etal., Neurology. 2017 Oct 24;89(17):1829-1839. doi: 10.1212/WNL.0000000000004560. Epub 2017 Sep 27.
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Increased decidual mRNA expression levels of candidate maternal pre-eclampsia susceptibility genes are associated with clinical severity. Yong HE, etal., Placenta. 2014 Feb;35(2):117-24. doi: 10.1016/j.placenta.2013.11.008. Epub 2013 Nov 25.
Additional References at PubMed
PMID:10625665   PMID:10970885   PMID:11732842   PMID:12101409   PMID:12477932   PMID:16041630   PMID:17525254   PMID:18757743   PMID:20551380   PMID:23154389   PMID:23376485   PMID:23533145  
PMID:23658023   PMID:23979707   PMID:24006456   PMID:27068509   PMID:27559042   PMID:31285761   PMID:32947968  


Genomics

Comparative Map Data
Col4a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81684,749,672 - 84,885,520 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1684,749,672 - 84,885,520 (-)EnsemblGRCr8
mRatBN7.21678,047,591 - 78,183,360 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1678,047,602 - 78,183,839 (-)EnsemblmRatBN7.2
Rnor_6.01683,386,388 - 83,522,169 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1683,387,364 - 83,438,561 (-)Ensemblrn6Rnor6.0
Rnor_5.01682,852,230 - 82,987,790 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41682,899,206 - 83,045,102 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1675,846,004 - 75,981,238 (-)NCBICelera
RGSC_v3.11682,871,435 - 83,006,872 (-)NCBI
Cytogenetic Map16q12.5NCBI
COL4A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813110,307,284 - 110,513,209 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13110,305,812 - 110,513,209 (+)Ensemblhg38GRCh38
GRCh3713110,959,631 - 111,165,556 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613109,757,632 - 109,963,375 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3413109,757,631 - 109,963,372NCBI
Celera1391,803,804 - 92,011,436 (+)NCBICelera
Cytogenetic Map13q34NCBI
HuRef1391,559,092 - 91,764,904 (+)NCBIHuRef
CHM1_113110,928,062 - 111,133,226 (+)NCBICHM1_1
T2T-CHM13v2.013109,536,748 - 109,743,647 (+)NCBIT2T-CHM13v2.0
Col4a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39811,362,878 - 11,499,287 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl811,362,805 - 11,499,287 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38811,312,805 - 11,449,287 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl811,312,805 - 11,449,287 (+)Ensemblmm10GRCm38
MGSCv37811,312,829 - 11,449,287 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36811,312,996 - 11,449,187 (+)NCBIMGSCv36mm8
Celera811,487,441 - 11,623,992 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.62NCBI
Col4a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554042,092,184 - 2,178,079 (-)Ensembl
ChiLan1.0NW_0049554042,092,184 - 2,178,079 (-)NCBIChiLan1.0ChiLan1.0
COL4A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214111,800,177 - 112,009,811 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113110,482,934 - 110,693,543 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01391,440,314 - 91,650,138 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113110,562,681 - 110,768,362 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13110,563,119 - 110,767,530 (+)EnsemblpanPan2panpan1.1
COL4A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12258,656,579 - 58,820,560 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2258,697,175 - 58,773,297 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2258,360,350 - 58,530,121 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02259,273,416 - 59,443,367 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2259,273,522 - 59,443,348 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12258,775,158 - 58,944,081 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02258,766,023 - 58,936,137 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02258,801,350 - 58,971,538 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Col4a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945193,535,946 - 193,681,319 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364722,270,819 - 2,416,349 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364722,270,836 - 2,416,324 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COL4A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1176,997,516 - 77,161,614 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11176,996,885 - 77,161,617 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21184,613,792 - 84,675,826 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COL4A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1388,564,328 - 88,760,191 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl388,563,903 - 88,760,411 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604645,280,036 - 45,477,365 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Col4a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247932,202,244 - 2,324,507 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247932,201,815 - 2,325,002 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Col4a2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11372,409,913 - 72,545,210 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:167
Count of miRNA genes:138
Interacting mature miRNAs:148
Transcripts:ENSRNOT00000057461
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)164445512389455123Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165942871491442908Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)164445512389455123Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)164199206486992064Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165942871491442908Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165942871491442908Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164909919691442908Rat

Markers in Region
AU048080  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21678,074,066 - 78,074,228 (+)MAPPERmRatBN7.2
Rnor_6.01683,412,816 - 83,412,977NCBIRnor6.0
Rnor_5.01682,878,522 - 82,878,683UniSTSRnor5.0
RGSC_v3.41682,925,747 - 82,925,908UniSTSRGSC3.4
Celera1675,872,462 - 75,872,623UniSTS
Cytogenetic Map16q12.5UniSTS
G49320  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21678,091,671 - 78,092,027 (+)MAPPERmRatBN7.2
Rnor_6.01683,430,425 - 83,430,780NCBIRnor6.0
Rnor_5.01682,896,131 - 82,896,486UniSTSRnor5.0
RGSC_v3.41682,943,351 - 82,943,706UniSTSRGSC3.4
Celera1675,890,062 - 75,890,417UniSTS
Cytogenetic Map16q12.5UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 57 59 6 321 157 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000057461   ⟹   ENSRNOP00000054270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1684,749,672 - 84,885,520 (-)Ensembl
mRatBN7.2 Ensembl1678,047,602 - 78,183,839 (-)Ensembl
Rnor_6.0 Ensembl1683,387,364 - 83,438,561 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100688   ⟹   ENSRNOP00000092605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1684,749,672 - 84,885,520 (-)Ensembl
mRatBN7.2 Ensembl1678,047,602 - 78,183,839 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102469   ⟹   ENSRNOP00000092699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1684,749,672 - 84,802,239 (-)Ensembl
mRatBN7.2 Ensembl1678,047,602 - 78,100,441 (-)Ensembl
RefSeq Acc Id: NM_001427256   ⟹   NP_001414185
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81684,749,672 - 84,885,520 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001414185 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB47427 (Get FASTA)   NCBI Sequence Viewer  
  EDM08821 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000054270
  ENSRNOP00000054270.5
  ENSRNOP00000092605.2
  ENSRNOP00000092699.2
Ensembl Acc Id: ENSRNOP00000054270   ⟸   ENSRNOT00000057461
Ensembl Acc Id: ENSRNOP00000092605   ⟸   ENSRNOT00000100688
Ensembl Acc Id: ENSRNOP00000092699   ⟸   ENSRNOT00000102469
RefSeq Acc Id: NP_001414185   ⟸   NM_001427256
- Peptide Label: precursor
- UniProtKB: F1M6Q3 (UniProtKB/TrEMBL),   A6IWQ1 (UniProtKB/TrEMBL)
Protein Domains
Collagen IV NC1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M6Q3-F1-model_v2 AlphaFold F1M6Q3 1-1645 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308085 AgrOrtholog
BioCyc Gene G2FUF-10652 BioCyc
Ensembl Genes ENSRNOG00000023972 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057461 ENTREZGENE
  ENSRNOT00000057461.6 UniProtKB/TrEMBL
  ENSRNOT00000100688.2 UniProtKB/TrEMBL
  ENSRNOT00000102469.2 UniProtKB/TrEMBL
Gene3D-CATH 2.170.240.10 UniProtKB/TrEMBL
InterPro C-type_lectin_fold UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
  Collagen_IV_NC_sf UniProtKB/TrEMBL
  Collagen_superfamily UniProtKB/TrEMBL
  Collagen_VI_NC UniProtKB/TrEMBL
NCBI Gene 306628 ENTREZGENE
PANTHER COLLAGEN ALPHA UniProtKB/TrEMBL
  COLLAGEN ALPHA-2(IV) CHAIN UniProtKB/TrEMBL
  COLLAGEN ALPHA-2(IV) CHAIN UniProtKB/TrEMBL
Pfam Collagen UniProtKB/TrEMBL
  PF01413 UniProtKB/TrEMBL
PhenoGen Col4a2 PhenoGen
PROSITE NC1_IV UniProtKB/TrEMBL
RatGTEx ENSRNOG00000023972 RatGTEx
SMART SM00111 UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/TrEMBL
UniProt A0A8I6AHV3_RAT UniProtKB/TrEMBL
  A0A8I6AVZ9_RAT UniProtKB/TrEMBL
  A6IWQ1 ENTREZGENE, UniProtKB/TrEMBL
  F1M6Q3 ENTREZGENE, UniProtKB/TrEMBL
  Q62676_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-27 Col4a2  collagen type IV alpha 2 chain  Col4a2  collagen, type IV, alpha 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-25 Col4a2  collagen, type IV, alpha 2  Col4a2_predicted  procollagen, type IV, alpha 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Col4a2_predicted  procollagen, type IV, alpha 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED