Smox (spermine oxidase) - Rat Genome Database

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Gene: Smox (spermine oxidase) Rattus norvegicus
Analyze
Symbol: Smox
Name: spermine oxidase
RGD ID: 1306049
Description: Enables polyamine oxidase activity. Involved in spermine catabolic process. Predicted to be located in cytosol; nuclear membrane; and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human SMOX (spermine oxidase); PARTICIPATES IN polyamine metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC308652
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83139,184,793 - 139,220,174 (+)NCBIGRCr8
mRatBN7.23118,731,814 - 118,767,242 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,731,900 - 118,765,710 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 EnsemblX98,014,440 - 98,016,678 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,644,969 - 122,659,253 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03131,240,782 - 131,254,873 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,901,066 - 128,915,350 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03124,068,796 - 124,103,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3124,068,865 - 124,102,240 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,561,424 - 130,596,385 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43119,240,376 - 119,254,370 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13119,125,546 - 119,159,950 (+)NCBI
Celera3117,557,725 - 117,571,162 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-alpha-phellandrene  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
8-Br-cAMP  (ISO)
acetaldehyde  (ISO)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
alpha-Zearalanol  (EXP)
amiodarone  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromobenzene  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
cisplatin  (ISO)
clomiphene  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDT  (EXP)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dichloroacetic acid  (ISO)
Didecyldimethylammonium  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP)
disodium selenite  (ISO)
disulfiram  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
estrone  (ISO)
ethanol  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
hexestrol  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
medroxyprogesterone acetate  (ISO)
menadione  (ISO)
mestranol  (ISO)
methamphetamine  (ISO)
methylisothiazolinone  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
PhIP  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
spermidine  (ISO)
spermine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP,ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Effect of mitoguazone on polyamine oxidase activity in rat liver. Ferioli ME, etal., Toxicol Appl Pharmacol. 2004 Dec 1;201(2):105-11.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. A perspective of polyamine metabolism. Wallace HM, etal., Biochem J. 2003 Nov 15;376(Pt 1):1-14.
Additional References at PubMed
PMID:12141946   PMID:12477380   PMID:12477932   PMID:14764092   PMID:18422650   PMID:37102659  


Genomics

Comparative Map Data
Smox
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83139,184,793 - 139,220,174 (+)NCBIGRCr8
mRatBN7.23118,731,814 - 118,767,242 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,731,900 - 118,765,710 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 EnsemblX98,014,440 - 98,016,678 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,644,969 - 122,659,253 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03131,240,782 - 131,254,873 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,901,066 - 128,915,350 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03124,068,796 - 124,103,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3124,068,865 - 124,102,240 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,561,424 - 130,596,385 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43119,240,376 - 119,254,370 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13119,125,546 - 119,159,950 (+)NCBI
Celera3117,557,725 - 117,571,162 (+)NCBICelera
Cytogenetic Map3q36NCBI
SMOX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38204,148,828 - 4,187,727 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl204,120,980 - 4,187,747 (+)EnsemblGRCh38hg38GRCh38
GRCh37204,129,475 - 4,168,374 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36204,077,450 - 4,116,369 (+)NCBINCBI36Build 36hg18NCBI36
Build 34204,077,449 - 4,116,369NCBI
Celera204,194,572 - 4,233,196 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef204,078,022 - 4,117,146 (+)NCBIHuRef
CHM1_1204,129,726 - 4,168,682 (+)NCBICHM1_1
T2T-CHM13v2.0204,183,413 - 4,222,031 (+)NCBIT2T-CHM13v2.0
Smox
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392131,333,624 - 131,367,103 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2131,333,416 - 131,367,842 (+)EnsemblGRCm39 Ensembl
GRCm382131,491,858 - 131,525,183 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2131,491,496 - 131,525,922 (+)EnsemblGRCm38mm10GRCm38
MGSCv372131,317,598 - 131,350,919 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362131,183,384 - 131,216,613 (+)NCBIMGSCv36mm8
Celera2132,717,911 - 132,751,183 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.45NCBI
Smox
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541514,937,131 - 14,989,972 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541514,937,438 - 14,971,874 (+)NCBIChiLan1.0ChiLan1.0
SMOX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2215,094,689 - 5,134,252 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1205,091,525 - 5,131,097 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0204,167,417 - 4,206,956 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1203,965,616 - 4,004,468 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl203,965,616 - 4,004,468 (+)Ensemblpanpan1.1panPan2
SMOX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12417,240,910 - 17,291,258 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2417,252,537 - 17,300,451 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,064,337 - 17,122,972 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02417,659,530 - 17,718,356 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2417,670,961 - 17,710,018 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12417,253,747 - 17,312,426 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02417,359,712 - 17,418,236 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02417,693,183 - 17,752,085 (-)NCBIUU_Cfam_GSD_1.0
Smox
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640166,135,194 - 166,171,941 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648514,566,277 - 14,603,338 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648514,566,570 - 14,603,323 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMOX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1731,548,636 - 31,591,975 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11731,552,927 - 31,592,007 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21735,886,931 - 35,899,388 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SMOX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660719,499,568 - 9,538,963 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smox
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247415,215,393 - 5,251,552 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247415,215,924 - 5,250,970 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Smox
199 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:234
Count of miRNA genes:155
Interacting mature miRNAs:164
Transcripts:ENSRNOT00000028876
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)384091273129091273Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat

Markers in Region
RH130305  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,765,505 - 118,765,660 (+)MAPPERmRatBN7.2
mRatBN7.2X98,016,195 - 98,016,350 (+)MAPPERmRatBN7.2
Rnor_6.0X105,652,911 - 105,653,065NCBIRnor6.0
Rnor_6.03124,102,040 - 124,102,194NCBIRnor6.0
Rnor_5.03130,594,699 - 130,594,853UniSTSRnor5.0
Rnor_5.0X105,542,178 - 105,542,332UniSTSRnor5.0
RGSC_v3.43119,254,170 - 119,254,324UniSTSRGSC3.4
RGSC_v3.4X122,296,883 - 122,297,037UniSTSRGSC3.4
CeleraX99,055,639 - 99,055,793UniSTS
Celera3117,570,962 - 117,571,116UniSTS
RH 3.4 Map31021.91UniSTS
Cytogenetic Map3q36UniSTS
Cytogenetic MapXq34UniSTS
BI292153  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,762,797 - 118,762,960 (+)MAPPERmRatBN7.2
Rnor_6.03124,099,332 - 124,099,494NCBIRnor6.0
Rnor_5.03130,591,991 - 130,592,153UniSTSRnor5.0
RGSC_v3.43119,251,462 - 119,251,624UniSTSRGSC3.4
Celera3117,568,254 - 117,568,416UniSTS
RH 3.4 Map31013.0UniSTS
Cytogenetic Map3q36UniSTS
Smox  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X98,015,422 - 98,016,030 (+)MAPPERmRatBN7.2
Rnor_6.0X105,652,138 - 105,652,745NCBIRnor6.0
Rnor_5.0X105,541,405 - 105,542,012UniSTSRnor5.0
CeleraX99,054,866 - 99,055,473UniSTS
Cytogenetic MapXq34UniSTS
Cytogenetic Map3q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001134854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC160836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC161894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000028876   ⟹   ENSRNOP00000028876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,751,623 - 118,765,706 (+)Ensembl
Rnor_6.0 Ensembl3124,088,157 - 124,102,240 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079264   ⟹   ENSRNOP00000070554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,731,900 - 118,765,710 (+)Ensembl
Rnor_6.0 Ensembl3124,068,865 - 124,099,541 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096195   ⟹   ENSRNOP00000077137
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,731,900 - 118,762,673 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104527   ⟹   ENSRNOP00000090716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,751,623 - 118,765,706 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109582   ⟹   ENSRNOP00000086718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,731,900 - 118,765,420 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117336   ⟹   ENSRNOP00000093779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,731,900 - 118,765,420 (+)Ensembl
RefSeq Acc Id: NM_001134854   ⟹   NP_001128326
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,204,601 - 139,218,684 (+)NCBI
mRatBN7.23118,751,623 - 118,765,706 (+)NCBI
Rnor_6.03124,088,157 - 124,102,240 (+)NCBI
Rnor_5.03130,561,424 - 130,596,385 (+)NCBI
RGSC_v3.43119,240,376 - 119,254,370 (+)RGD
Celera3117,557,725 - 117,571,162 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235063   ⟹   XP_006235125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,184,793 - 139,218,689 (+)NCBI
mRatBN7.23118,731,814 - 118,765,733 (+)NCBI
Rnor_6.03124,068,796 - 124,102,267 (+)NCBI
Rnor_5.03130,561,424 - 130,596,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235064   ⟹   XP_006235126
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,184,793 - 139,218,689 (+)NCBI
mRatBN7.23118,731,814 - 118,765,733 (+)NCBI
Rnor_6.03124,068,796 - 124,102,267 (+)NCBI
Rnor_5.03130,561,424 - 130,596,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235065   ⟹   XP_006235127
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,184,793 - 139,220,174 (+)NCBI
mRatBN7.23118,731,814 - 118,767,242 (+)NCBI
Rnor_6.03124,068,796 - 124,103,726 (+)NCBI
Rnor_5.03130,561,424 - 130,596,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104803   ⟹   XP_038960731
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,206,217 - 139,218,689 (+)NCBI
mRatBN7.23118,753,254 - 118,765,733 (+)NCBI
RefSeq Acc Id: XM_039104804   ⟹   XP_038960732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,204,972 - 139,218,689 (+)NCBI
mRatBN7.23118,751,995 - 118,765,733 (+)NCBI
RefSeq Acc Id: XM_039104806   ⟹   XP_038960734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,184,793 - 139,218,689 (+)NCBI
mRatBN7.23118,731,818 - 118,765,733 (+)NCBI
RefSeq Acc Id: XM_039104807   ⟹   XP_038960735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,184,793 - 139,218,398 (+)NCBI
mRatBN7.23118,731,814 - 118,765,429 (+)NCBI
RefSeq Acc Id: XM_039104808   ⟹   XP_038960736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,184,793 - 139,218,689 (+)NCBI
mRatBN7.23118,731,814 - 118,765,733 (+)NCBI
RefSeq Acc Id: XM_039104809   ⟹   XP_038960737
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,184,793 - 139,220,174 (+)NCBI
mRatBN7.23118,731,814 - 118,767,242 (+)NCBI
RefSeq Acc Id: XM_063283536   ⟹   XP_063139606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,202,667 - 139,218,689 (+)NCBI
RefSeq Acc Id: XM_063283537   ⟹   XP_063139607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,202,667 - 139,218,689 (+)NCBI
RefSeq Acc Id: XM_063283538   ⟹   XP_063139608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,206,215 - 139,218,689 (+)NCBI
RefSeq Acc Id: XM_063283539   ⟹   XP_063139609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,202,667 - 139,218,689 (+)NCBI
RefSeq Acc Id: XM_063283540   ⟹   XP_063139610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83139,204,972 - 139,218,689 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001128326 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418521 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418522 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418523 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418524 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418525 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418526 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418527 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418528 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418529 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418530 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418531 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418532 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235125 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235126 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235127 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960731 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960732 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960734 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960735 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960736 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960737 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139606 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139607 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139608 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139609 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139610 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI60836 (Get FASTA)   NCBI Sequence Viewer  
  AAI61894 (Get FASTA)   NCBI Sequence Viewer  
  EDL80241 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000028876.2
  ENSRNOP00000070554.2
  ENSRNOP00000077137.1
  ENSRNOP00000082749.1
  ENSRNOP00000086718.1
  ENSRNOP00000090716.1
  ENSRNOP00000093779.1
RefSeq Acc Id: NP_001128326   ⟸   NM_001134854
- UniProtKB: B1WBU6 (UniProtKB/TrEMBL),   A6HQE1 (UniProtKB/TrEMBL),   A0A8I5ZYI4 (UniProtKB/TrEMBL),   F7F9S8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235125   ⟸   XM_006235063
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006235127   ⟸   XM_006235065
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006235126   ⟸   XM_006235064
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000070554   ⟸   ENSRNOT00000079264
Ensembl Acc Id: ENSRNOP00000028876   ⟸   ENSRNOT00000028876
RefSeq Acc Id: XP_038960737   ⟸   XM_039104809
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZYI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960736   ⟸   XM_039104808
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZYI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960735   ⟸   XM_039104807
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZYI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960734   ⟸   XM_039104806
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038960732   ⟸   XM_039104804
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038960731   ⟸   XM_039104803
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZYI4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000086718   ⟸   ENSRNOT00000109582
Ensembl Acc Id: ENSRNOP00000093779   ⟸   ENSRNOT00000117336
Ensembl Acc Id: ENSRNOP00000090716   ⟸   ENSRNOT00000104527
Ensembl Acc Id: ENSRNOP00000077137   ⟸   ENSRNOT00000096195
RefSeq Acc Id: XP_063139606   ⟸   XM_063283536
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JY83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139607   ⟸   XM_063283537
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063139609   ⟸   XM_063283539
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063139610   ⟸   XM_063283540
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063139608   ⟸   XM_063283538
- Peptide Label: isoform X4
Protein Domains
Amine oxidase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1WBU6-F1-model_v2 AlphaFold B1WBU6 1-555 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692452
Promoter ID:EPDNEW_R2975
Type:initiation region
Name:Smox_1
Description:spermine oxidase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03124,068,807 - 124,068,867EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306049 AgrOrtholog
BioCyc Gene G2FUF-47801 BioCyc
BioCyc Pathway PWY-6117 [spermine and spermidine degradation I] BioCyc
BioCyc Pathway Image PWY-6117 BioCyc
Ensembl Genes ENSRNOG00000021255 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000059641 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028876.4 UniProtKB/TrEMBL
  ENSRNOT00000079264.2 UniProtKB/TrEMBL
  ENSRNOT00000091530.2 UniProtKB/TrEMBL
  ENSRNOT00000096195.1 UniProtKB/TrEMBL
  ENSRNOT00000104527.1 UniProtKB/TrEMBL
  ENSRNOT00000109582.1 UniProtKB/TrEMBL
  ENSRNOT00000117336.1 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/TrEMBL
  3.90.660.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7193521 IMAGE-MGC_LOAD
  IMAGE:7456805 IMAGE-MGC_LOAD
InterPro Amino_oxidase UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/TrEMBL
  Flavin_monoamine_oxidase UniProtKB/TrEMBL
KEGG Report rno:308652 UniProtKB/TrEMBL
MGC_CLONE MGC:187476 IMAGE-MGC_LOAD
  MGC:187552 IMAGE-MGC_LOAD
NCBI Gene 308652 ENTREZGENE
PANTHER FLAVIN MONOAMINE OXIDASE UniProtKB/TrEMBL
  SPERMINE OXIDASE UniProtKB/TrEMBL
Pfam Amino_oxidase UniProtKB/TrEMBL
PhenoGen Smox PhenoGen
PRINTS ADXRDTASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021255 RatGTEx
  ENSRNOG00000059641 RatGTEx
Superfamily-SCOP FAD-linked reductases, C-terminal domain UniProtKB/TrEMBL
  SSF51905 UniProtKB/TrEMBL
UniProt A0A0G2JY83 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y9C4_RAT UniProtKB/TrEMBL
  A0A8I5ZYI4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A6T7_RAT UniProtKB/TrEMBL
  A0A8I6AE29_RAT UniProtKB/TrEMBL
  A0A8I6AJG4_RAT UniProtKB/TrEMBL
  A6HQE1 ENTREZGENE, UniProtKB/TrEMBL
  A6HQE3_RAT UniProtKB/TrEMBL
  B1H229 ENTREZGENE, UniProtKB/TrEMBL
  B1WBU6 ENTREZGENE
  F7F9S8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B1WBU6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Smox  spermine oxidase   Smox_predicted  spermine oxidase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Smox_predicted  spermine oxidase (predicted)      Symbol and Name status set to approved 70820 APPROVED