Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fgfr1op2 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of FGFR1OP2 mRNA | CTD | PMID:22206623 | Fgfr1op2 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of FGFR1OP2 mRNA | CTD | PMID:17555576 | Fgfr1op2 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Fgfr1op2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FGFR1OP2 mRNA | CTD | PMID:17942748 | Fgfr1op2 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of FGFR1OP2 mRNA | CTD | PMID:17942748 | Fgfr1op2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FGFR1OP2 mRNA | CTD | PMID:17949056 | Fgfr1op2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FGFR1OP2 mRNA | CTD | PMID:34747641 | Fgfr1op2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGFR1OP2 mRNA | CTD | PMID:21570461 | Fgfr1op2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Fgfr1op2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FGFR1OP2 mRNA | CTD | PMID:17942748 | Fgfr1op2 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of FGFR1OP2 mRNA | CTD | PMID:21346803 | Fgfr1op2 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of FGFR1OP2 mRNA | CTD | PMID:21346803 | Fgfr1op2 | Rat | aflatoxin B1 | increases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of FGFR1OP2 mRNA | CTD | PMID:19770486 | Fgfr1op2 | Rat | aflatoxin B1 | increases methylation | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of FGFR1OP2 gene | CTD | PMID:27153756 | Fgfr1op2 | Rat | amiodarone | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of FGFR1OP2 mRNA | CTD | PMID:19774075 | Fgfr1op2 | Rat | arsane | affects methylation | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of FGFR1OP2 gene | CTD | PMID:25304211 | Fgfr1op2 | Rat | arsenic atom | affects methylation | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of FGFR1OP2 gene | CTD | PMID:25304211 | Fgfr1op2 | Rat | arsenous acid | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of FGFR1OP2 mRNA | CTD | PMID:20458559 | Fgfr1op2 | Rat | benzo[a]pyrene | increases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of FGFR1OP2 mRNA | CTD | PMID:19770486 and PMID:22228805 | Fgfr1op2 | Rat | benzo[a]pyrene | decreases methylation | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of FGFR1OP2 5' UTR | CTD | PMID:27901495 | Fgfr1op2 | Rat | benzo[a]pyrene | multiple interactions | ISO | Fgfr1op2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:27858113 | Fgfr1op2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20018196 | Fgfr1op2 | Rat | benzo[b]fluoranthene | decreases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:26377693 | Fgfr1op2 | Rat | benzo[b]fluoranthene | multiple interactions | ISO | Fgfr1op2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:27858113 | Fgfr1op2 | Rat | bisphenol A | increases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of FGFR1OP2 mRNA | CTD | PMID:21932408 | Fgfr1op2 | Rat | bisphenol A | multiple interactions | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | [ginger extract results in increased abundance of Oils and Volatile] inhibits the reaction [bisphenol A results in increased expression of FGFR1OP2 protein] | CTD | PMID:33376534 | Fgfr1op2 | Rat | bisphenol A | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of FGFR1OP2 protein | CTD | PMID:33376534 | Fgfr1op2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FGFR1OP2 mRNA | CTD | PMID:25181051 and PMID:30816183 | Fgfr1op2 | Rat | bisphenol A | increases methylation | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of FGFR1OP2 gene | CTD | PMID:22576693 | Fgfr1op2 | Rat | bisphenol A | decreases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:22576693 and PMID:29275510 | Fgfr1op2 | Rat | bortezomib | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of FGFR1OP2 mRNA | CTD | PMID:20977926 | Fgfr1op2 | Rat | cadmium dichloride | decreases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:38382870 | Fgfr1op2 | Rat | carbon nanotube | decreases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:25554681 | Fgfr1op2 | Rat | chrysene | multiple interactions | ISO | Fgfr1op2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:27858113 | Fgfr1op2 | Rat | copper atom | multiple interactions | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of FGFR1OP2 mRNA | CTD | PMID:20971185 | Fgfr1op2 | Rat | copper(0) | multiple interactions | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of FGFR1OP2 mRNA | CTD | PMID:20971185 | Fgfr1op2 | Rat | cyclosporin A | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of FGFR1OP2 mRNA | CTD | PMID:20106945 and PMID:25562108 | Fgfr1op2 | Rat | diarsenic trioxide | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of FGFR1OP2 mRNA | CTD | PMID:20458559 | Fgfr1op2 | Rat | Dibutyl phosphate | affects expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of FGFR1OP2 mRNA | CTD | PMID:37042841 | Fgfr1op2 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of FGFR1OP2 mRNA | CTD | PMID:21266533 | Fgfr1op2 | Rat | diclofenac | decreases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Diclofenac results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:26934552 | Fgfr1op2 | Rat | dicrotophos | decreases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:28302478 | Fgfr1op2 | Rat | ethanol | affects splicing | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Ethanol affects the splicing of FGFR1OP2 mRNA | CTD | PMID:30319688 | Fgfr1op2 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of FGFR1OP2 mRNA | CTD | PMID:24136188 | Fgfr1op2 | Rat | folic acid | decreases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:25629700 | Fgfr1op2 | Rat | glyphosate | affects expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Glyphosate affects the expression of FGFR1OP2 mRNA | CTD | PMID:35489704 | Fgfr1op2 | Rat | hydrogen peroxide | decreases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:18951874 | Fgfr1op2 | Rat | lead(0) | affects splicing | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Lead affects the splicing of FGFR1OP2 mRNA | CTD | PMID:28903495 | Fgfr1op2 | Rat | methidathion | decreases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | methidathion results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:34813904 | Fgfr1op2 | Rat | methyl methanesulfonate | decreases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:23649840 | Fgfr1op2 | Rat | methylparaben | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | methylparaben results in increased expression of FGFR1OP2 mRNA | CTD | PMID:31745603 | Fgfr1op2 | Rat | paracetamol | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of FGFR1OP2 mRNA | CTD | PMID:21420995 | Fgfr1op2 | Rat | paracetamol | affects expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Acetaminophen affects the expression of FGFR1OP2 mRNA | CTD | PMID:25458485 | Fgfr1op2 | Rat | pentachlorophenol | increases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of FGFR1OP2 mRNA | CTD | PMID:23892564 | Fgfr1op2 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:25812627 | Fgfr1op2 | Rat | perfluorooctane-1-sulfonic acid | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in increased expression of FGFR1OP2 mRNA | CTD | PMID:25812627 | Fgfr1op2 | Rat | perfluorooctanoic acid | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of FGFR1OP2 mRNA | CTD | PMID:25812627 | Fgfr1op2 | Rat | phenobarbital | decreases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:23091169 | Fgfr1op2 | Rat | quercetin | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of FGFR1OP2 mRNA | CTD | PMID:30152185 | Fgfr1op2 | Rat | resveratrol | multiple interactions | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of FGFR1OP2 mRNA | CTD | PMID:23557933 | Fgfr1op2 | Rat | silicon dioxide | decreases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:19073995 | Fgfr1op2 | Rat | sodium arsenite | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of FGFR1OP2 mRNA | CTD | PMID:38568856 | Fgfr1op2 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:19281266 | Fgfr1op2 | Rat | sunitinib | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of FGFR1OP2 mRNA | CTD | PMID:31533062 | Fgfr1op2 | Rat | tamoxifen | affects expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Tamoxifen affects the expression of FGFR1OP2 mRNA | CTD | PMID:17555576 | Fgfr1op2 | Rat | testosterone | decreases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:33359661 | Fgfr1op2 | Rat | tetrachloromethane | increases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of FGFR1OP2 mRNA | CTD | PMID:31919559 | Fgfr1op2 | Rat | tetraphene | decreases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:26377693 | Fgfr1op2 | Rat | tetraphene | multiple interactions | ISO | Fgfr1op2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:27858113 | Fgfr1op2 | Rat | thimerosal | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Thimerosal results in increased expression of FGFR1OP2 mRNA | CTD | PMID:27188386 | Fgfr1op2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of FGFR1OP2 mRNA | CTD | PMID:34492290 | Fgfr1op2 | Rat | thiram | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Thiram results in increased expression of FGFR1OP2 mRNA | CTD | PMID:38568856 | Fgfr1op2 | Rat | trichostatin A | affects expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | trichostatin A affects the expression of FGFR1OP2 mRNA | CTD | PMID:28542535 | Fgfr1op2 | Rat | triphenyl phosphate | affects expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of FGFR1OP2 mRNA | CTD | PMID:37042841 | Fgfr1op2 | Rat | triptonide | increases expression | ISO | Fgfr1op2 (Mus musculus) | 6480464 | triptonide results in increased expression of FGFR1OP2 mRNA | CTD | PMID:33045310 | Fgfr1op2 | Rat | urethane | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Urethane results in increased expression of FGFR1OP2 mRNA | CTD | PMID:28818685 | Fgfr1op2 | Rat | valproic acid | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FGFR1OP2 mRNA | CTD | PMID:29154799 | Fgfr1op2 | Rat | valproic acid | affects expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of FGFR1OP2 mRNA | CTD | PMID:23179753 | Fgfr1op2 | Rat | valproic acid | decreases methylation | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of FGFR1OP2 gene | CTD | PMID:29154799 | Fgfr1op2 | Rat | valproic acid | decreases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of FGFR1OP2 mRNA | CTD | PMID:27188386 and PMID:28001369 | Fgfr1op2 | Rat | vorinostat | increases expression | ISO | FGFR1OP2 (Homo sapiens) | 6480464 | vorinostat results in increased expression of FGFR1OP2 mRNA | CTD | PMID:27188386 | |