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Gene: Msh5 (mutS homolog 5) Ictidomys tridecemlineatus

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Symbol:

Msh5

Name:

mutS homolog 5

RGD ID:

12625075

Description:

ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent DNA damage sensor activity (inferred); DNA binding (inferred); INVOLVED IN female gamete generation (ortholog); homologous chromosome pairing at meiosis (ortholog); meiosis I (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); hereditary breast ovarian cancer syndrome (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN synaptonemal complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

mutS protein homolog 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MSH5 (mutS homolog 5)	NCBI	Ortholog
Mus musculus (house mouse):	Msh5 (mutS homolog 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Msh5 (mutS homolog 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Msh5 (mutS homolog 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MSH5 (mutS homolog 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MSH5 (mutS homolog 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MSH5 (mutS homolog 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MSH5 (mutS homolog 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Msh5 (mutS homolog 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Msh5 (mutS homolog 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	35,767,176 - 35,785,306 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936727	1,777,570 - 1,793,711 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936727	1,776,038 - 1,794,152 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hepatocellular carcinoma (ISO)

hereditary breast ovarian cancer syndrome (ISO)

lung non-small cell carcinoma (ISO)

primary ovarian insufficiency 13 (ISO)

spermatogenic failure 74 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chiasma assembly (IEA)

DNA damage response (IEA)

DNA repair (IEA)

female gamete generation (ISO)

homologous chromosome pairing at meiosis (ISO)

meiosis I (IEA,ISO)

meiotic cell cycle (IEA)

mismatch repair (IEA)

Cellular Component

nucleus (IEA)

synaptonemal complex (ISO)

Molecular Function

ATP binding (IEA)

ATP-dependent DNA damage sensor activity (IEA)

DNA binding (IEA)

double-stranded DNA binding (IEA)

mismatched DNA binding (IEA)

nucleotide binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Msh5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	35,767,176 - 35,785,306 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936727	1,777,570 - 1,793,711 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936727	1,776,038 - 1,794,152 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MSH5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	31,740,005 - 31,762,676 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	31,739,677 - 31,762,676 (+)	Ensembl			hg38	GRCh38
GRCh37	6	31,707,782 - 31,730,453 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	31,815,753 - 31,838,432 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	31,815,755 - 31,840,601	NCBI
Celera	6	33,305,954 - 33,328,700 (+)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	31,493,957 - 31,516,883 (+)	NCBI		HuRef
CHM1_1	6	31,709,839 - 31,732,578 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	31,593,029 - 31,615,723 (+)	NCBI		T2T-CHM13v2.0

Msh5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	35,247,581 - 35,267,842 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	35,247,581 - 35,265,721 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	35,028,605 - 35,046,997 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	35,028,605 - 35,046,745 (-)	Ensembl			mm10	GRCm38
MGSCv37	17	35,165,550 - 35,183,668 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	34,636,661 - 34,654,678 (-)	NCBI		MGSCv36	mm8
Celera	17	38,124,846 - 38,143,436 (-)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	18.57	NCBI

Msh5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	3,779,180 - 3,797,996 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	3,781,578 - 3,797,994 (+)	Ensembl				GRCr8
mRatBN7.2	20	3,773,867 - 3,793,337 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	3,776,942 - 3,793,336 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	4,476,493 - 4,492,884 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	3,838,546 - 3,854,939 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	4,376,404 - 4,392,844 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	20	4,174,930 - 4,191,338 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	20	5,263,698 - 5,280,076 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	20	5,266,641 - 5,283,019 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	20	4,190,201 - 4,206,610 (+)	NCBI		F344_StmMcwi
Rnor_6.0	20	5,020,690 - 5,037,125 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	5,020,667 - 5,037,088 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	7,093,706 - 7,110,044 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	3,845,731 - 3,862,011 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	4,233,160 - 4,249,400 (-)	NCBI		Celera
RGSC_v3.1	20	3,846,041 - 3,862,242 (+)	NCBI
Cytogenetic Map	20	p12	NCBI

Msh5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	279,744 - 297,153 (+)	Ensembl
ChiLan1.0	NW_004955437	275,976 - 297,268 (+)	NCBI	ChiLan1.0	ChiLan1.0

MSH5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	46,217,203 - 46,239,558 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	42,178,711 - 42,201,176 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	31,401,343 - 31,424,665 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	32,289,318 - 32,313,411 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	32,290,511 - 32,311,085 (+)	Ensembl			panPan2	panpan1.1

MSH5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	1,221,278 - 1,243,042 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	1,357,836 - 1,379,567 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	1,364,526 - 1,386,294 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	1,364,451 - 1,386,294 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	1,223,762 - 1,245,520 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	1,290,998 - 1,312,682 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	1,358,882 - 1,380,614 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

MSH5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	23,852,918 - 23,872,760 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	23,852,864 - 23,872,760 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

MSH5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	40,260,979 - 40,283,872 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	40,261,125 - 40,282,511 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666044	31,652,919 - 31,675,016 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Msh5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	24,453,902 - 24,473,051 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624754	24,453,750 - 24,477,574 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Msh5
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	18	7,628,436 - 7,644,796 (-)	NCBI		Rrattus_CSIRO_v1

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013364656	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021735721	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021735722	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021735723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040282393	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040282394	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_078020273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_078020274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_078020275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_078020276	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_078020277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005732706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JBPVTT010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000013085 ⟹ ENSSTOP00000011727

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936727	1,777,570 - 1,793,711 (-)	Ensembl

RefSeq Acc Id:

XM_021735721 ⟹ XP_021591396

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	35,767,187 - 35,783,919 (+)	NCBI
SpeTri2.0	NW_004936727	1,776,038 - 1,794,137 (-)	NCBI

Sequence:

show sequence

CTGTTGTTGGTGGTGGTTGGGGCTGTTTCTCGCGTGTAGCGACTGAGGTGACGGAAAAGGCGGG
AAAATGTCGCGAGTTGGTGCCAGTGAGTTCCAAGCCCATGACCTTCCAAGCAACCCCAGGCAGG
ACGCCTCAGGGACTGGGACCTGGGGCGGCCTCGGCCAGGTTCCCCAACTTGGTCCCAGCACCAG
GCCCCGCGGAAGCCAATGAAGAGGAAGATGAGGAGGAGGAAGGACCAGCCGAGATCCATCTCTG
TGTGTTATGGAATTCAGGATACCTGGGCATTGCCTACTATGACACTAGTGACTCCATTGTTCAC
TTCATGCCAGATGCCCCAGACCATGAGAGCCTCAAGCTTCTTCAAAGAGTTGTGGATGAAATTA
ATCCCCGGTCTGTTGTTACCAGTGCCAAACAGGATGAGAATATGACTCGTTTTCTAGGGAAGCT
TGCCTCCCAGGAGCACAGAGAGCCAAAGAGACCTGAAATCATACTTTTGCCAAGTGTGGATTTT
GGTCTGGAGATAAGCAAACAACGTCTCCTTTCTGGAAACTACTCCTTTGTCCCGGAGTCCATGA
CTGCCACTGAAAAAATCCTTTTCCTCTCCTCCATTATTCCCTTTGACTGCCTTCTCACGGTCCG
GGCACTTGGAGGACTGCTCAAGTTCCTGGGTCGAAGAAGAATTGGAGTTGAACTGGAAGACTAT
AATGTCAGCATCCCCATCCTGGGCTTTAAGAAGTTTGTGTTGACCCATCTTGTGAGCATAGATC
AAGACACTTACAGTGTTTTACAGATTTTTAAGAGTGAGGCTCACCCCTCAGTATACAAAGTGGC
CAGTGGACTGAAGGAGGGGCTTAGCCTTTTTGGAATCCTCAACAGATGCCGCTGTAAGTGGGGA
GAGAAACTACTCAGGCTCTGGTTCACACGCCCAACTCAGGACCTGGGAGAACTCAATTCCCGTT
TGGATGTCATTCAATTTTTTTTGCTGCCCCAGAATCTGGACATGGCTCAGATGTTGCATCGGCT
TATGAGTCACATCAAGAATGTGCCTCTGATTCTGAAACGCATGAAGTTGTCCCACACCAAGGTC
AGTGACTGGCAGGTTCTGTACAAGACTGTGTACAGTGCCTTGGGACTAAGGGATGCTTGCCGCT
CCCTGCCCCAGTCCATTCAGCTTTTTCGGGACATTGCCCAAGAATTCTCTGATGACCTGCATCA
CATTGCCAGCCTCATTGGCAAAGTGGTGGACTTTGAGGGCAGTCTTGCTGAAAATCGTTTCACA
GTTCTCCCCAATGTAGACCCTGAAATTGATGAGAAAAAACGAAGGCTGATGGGTCTTCCCAGTT
TCCTCACTGAAGTTGCTCGGAAGGAGCTGGAGAATCTGGACTCCCGTATTCCATCATGCAGTGT
CATCTACATCCCTCTGATTGGCTTCCTTCTTTCTATTCCCCGCCTTCCTTCTATGGTAGAGGCT
GGTGACTTTGAAATTGAGGGACTGGATTTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGCA
GTGCTCGAACCAAGGAGCTGGATGCATTGCTTGGGGACCTGCACTGTGAGATCCGGGACCAGGA
GACCCTATTGATGTACCAGCTACAGTGCCAGGTGCTGGCGAGGGCAGCTGTCTTGACCCGAGTA
TTAGACCTTGCCTCCCGCCTGGATGCCCTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGCT
ACTCAAGGCCCCATTATTCCCCCCAGCTCCATGGGGTACGAATCCATAATGGCAGACATCCTCT
GATGGAACTATGTGCCCGAACCTTTGTGCCCAATTCTGCAGAATGTGGTGGGGACAAAGGCAAG
GTCAAAGTCGTCACTGGACCCAATTCCTCAGGAAAGAGCATATACCTTAAACAGGTAGGCTTGA
TCACGTTCATGGCCCTGGTGGGCAGCTTTGTACCAGCAGAGGAGGCTGAAATTGGGGCAGTAGA
TGCCATCTTCACCCGAATTCATAGCTGTGAATCCATCTCCCTTGGCCTCTCCACCTTCATGATC
GACCTCAACCAGCAGGTGGCAAAAGCAGTGAATAATGCCACTGAGCGATCTCTGGTTCTTATTG
ATGAATTCGGAAAGGGAACCAACACGGTGGATGGGCTTGCACTTTTGGCTGCTGTGCTCCGACA
CTGGTTGGTGCTTGGACCCATGTGCCCCCACATCTTTGTGGCCACCAACTTTCTGAGTCTTGTT
CAACTACAGCTGTTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATG
GGAACGACCTTGTCTTCTTCTATCAGGTTTGCGGAGGAGTTGCCAATGCCAGCTATGCCTCCCA
CACGGCTGCCCAGGCAGGGCTTCCTGAAAAACTCATTGCTCGTGGCAAAGAGATCTCGGACTTG
ATCCGCAATGGAAAACCTATCAAGCCTGTGAAGGAGTTGTTAAAGGAGAACCAAATGCAAAATT
GCCAGACATTAGTGGACAAGTTTCTGAAACTGGATTTGGAAGATCCCAGCCTGGACTTGGACAT
TTTCATGAGTCAGGAAGTGTTGCCTGCTGCCACCACCATCCTCTGAGTCCTTCCTCTGCCCTCC
CCAACTACTTGAGACCCAGGGGCTGCAATGTCTTTTTGGTTTTCTTATCTCCTTTAGACCCAGA
GTTCTCAATTTCTGTAGAAATTTTGTTTCATGTTAGGAATAAAGTTTATTTTGGATAATGTTAT
TGTTTCCTTAGGCAATCCAAAACAGAACAGGAGAATAGGACAGAGATGAAGCACCAAGCAGAAT
TCCACAGAGGAACCTGCCCTACCTCACTAAAAGTACATTGACACTGCTATGGGAAGACCCTCAG
ATTCTTCCCCAGGAGACTTCTTGAGAAAAAGCTACTTAAGAAAGGCCCTGTGAAAACAGAATAA
AGAAATGAAAGAGGGGTCCAAGAGAGATGGTTTTCCTCCTTATCTATGAATACCTCAGCCTTAG
AGAGACACCACAGGAAGGGGCCAGAGAGGCAGAATGGGTGTGAGGGAGGGGTAGAGGGGAGGGA
CCAGCTCAGGCCACAGCAGAGGGAGTGGCTACACCTTCCTCACCTCAGAGCCATGGGGAGCCAG
GGTTCTGGTGGGCAGCCCCTGGCACAGGCTCCCTACACAGTTCTGCTGCTGCCACTGGGAACAA
GCCGAGAAGACCCTGGGGCCCAGAGCTTTTTTCTTTGGCTGCAGAGGATGCAGGCTCTGGAGAG
AGAGCAGGATGCCCTGTGGCAGGGCCTGGAGCTGCTGGAACATGGCCGGGCCTGGTTTGAAGAC
CATCTGAGGGAGGCACAGCAACAGCAGCTGCATCTGGGAGCCCTTGGTGAGAATTTTCTAACAG
ATTTACACTCAGAGCCTGGCGGCCCCCAGTTAGCCCAAATT

hide sequence

RefSeq Acc Id:

XM_021735722 ⟹ XP_021591397

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	35,767,176 - 35,783,919 (+)	NCBI
SpeTri2.0	NW_004936727	1,776,038 - 1,794,152 (-)	NCBI

Sequence:

show sequence

CCTCCTGCAGGCTCGCTGTTGTTGGTGGTGGTTGGGGCTGTTTCTCGCGTGTAGCGACTGAGAG
TTCCAAGCCCATGACCTTCCAAGCAACCCCAGGCAGGACGCCTCAGGGACTGGGACCTGGGGCG
GCCTCGGCCAGGTTCCCCAACTTGGTCCCAGCACCAGGCCCCGCGGAAGCCAATGAAGAGGAAG
ATGAGGAGGAGGAAGGACCAGCCGAGATCCATCTCTGTGTGTTATGGAATTCAGGATACCTGGG
CATTGCCTACTATGACACTAGTGACTCCATTGTTCACTTCATGCCAGATGCCCCAGACCATGAG
AGCCTCAAGCTTCTTCAAAGAGTTGTGGATGAAATTAATCCCCGGTCTGTTGTTACCAGTGCCA
AACAGGATGAGAATATGACTCGTTTTCTAGGGAAGCTTGCCTCCCAGGAGCACAGAGAGCCAAA
GAGACCTGAAATCATACTTTTGCCAAGTGTGGATTTTGGTCTGGAGATAAGCAAACAACGTCTC
CTTTCTGGAAACTACTCCTTTGTCCCGGAGTCCATGACTGCCACTGAAAAAATCCTTTTCCTCT
CCTCCATTATTCCCTTTGACTGCCTTCTCACGGTCCGGGCACTTGGAGGACTGCTCAAGTTCCT
GGGTCGAAGAAGAATTGGAGTTGAACTGGAAGACTATAATGTCAGCATCCCCATCCTGGGCTTT
AAGAAGTTTGTGTTGACCCATCTTGTGAGCATAGATCAAGACACTTACAGTGTTTTACAGATTT
TTAAGAGTGAGGCTCACCCCTCAGTATACAAAGTGGCCAGTGGACTGAAGGAGGGGCTTAGCCT
TTTTGGAATCCTCAACAGATGCCGCTGTAAGTGGGGAGAGAAACTACTCAGGCTCTGGTTCACA
CGCCCAACTCAGGACCTGGGAGAACTCAATTCCCGTTTGGATGTCATTCAATTTTTTTTGCTGC
CCCAGAATCTGGACATGGCTCAGATGTTGCATCGGCTTATGAGTCACATCAAGAATGTGCCTCT
GATTCTGAAACGCATGAAGTTGTCCCACACCAAGGTCAGTGACTGGCAGGTTCTGTACAAGACT
GTGTACAGTGCCTTGGGACTAAGGGATGCTTGCCGCTCCCTGCCCCAGTCCATTCAGCTTTTTC
GGGACATTGCCCAAGAATTCTCTGATGACCTGCATCACATTGCCAGCCTCATTGGCAAAGTGGT
GGACTTTGAGGGCAGTCTTGCTGAAAATCGTTTCACAGTTCTCCCCAATGTAGACCCTGAAATT
GATGAGAAAAAACGAAGGCTGATGGGTCTTCCCAGTTTCCTCACTGAAGTTGCTCGGAAGGAGC
TGGAGAATCTGGACTCCCGTATTCCATCATGCAGTGTCATCTACATCCCTCTGATTGGCTTCCT
TCTTTCTATTCCCCGCCTTCCTTCTATGGTAGAGGCTGGTGACTTTGAAATTGAGGGACTGGAT
TTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGCAGTGCTCGAACCAAGGAGCTGGATGCAT
TGCTTGGGGACCTGCACTGTGAGATCCGGGACCAGGAGACCCTATTGATGTACCAGCTACAGTG
CCAGGTGCTGGCGAGGGCAGCTGTCTTGACCCGAGTATTAGACCTTGCCTCCCGCCTGGATGCC
CTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGCTACTCAAGGCCCCATTATTCCCCCCAGC
TCCATGGGGTACGAATCCATAATGGCAGACATCCTCTGATGGAACTATGTGCCCGAACCTTTGT
GCCCAATTCTGCAGAATGTGGTGGGGACAAAGGCAAGGTCAAAGTCGTCACTGGACCCAATTCC
TCAGGAAAGAGCATATACCTTAAACAGGTAGGCTTGATCACGTTCATGGCCCTGGTGGGCAGCT
TTGTACCAGCAGAGGAGGCTGAAATTGGGGCAGTAGATGCCATCTTCACCCGAATTCATAGCTG
TGAATCCATCTCCCTTGGCCTCTCCACCTTCATGATCGACCTCAACCAGGTGGCAAAAGCAGTG
AATAATGCCACTGAGCGATCTCTGGTTCTTATTGATGAATTCGGAAAGGGAACCAACACGGTGG
ATGGGCTTGCACTTTTGGCTGCTGTGCTCCGACACTGGTTGGTGCTTGGACCCATGTGCCCCCA
CATCTTTGTGGCCACCAACTTTCTGAGTCTTGTTCAACTACAGCTGTTGCCACAAGGGCCCCTG
GTGCAGTATTTGACCATGGAGACCTGTGAGGATGGGAACGACCTTGTCTTCTTCTATCAGGTTT
GCGGAGGAGTTGCCAATGCCAGCTATGCCTCCCACACGGCTGCCCAGGCAGGGCTTCCTGAAAA
ACTCATTGCTCGTGGCAAAGAGATCTCGGACTTGATCCGCAATGGAAAACCTATCAAGCCTGTG
AAGGAGTTGTTAAAGGAGAACCAAATGCAAAATTGCCAGACATTAGTGGACAAGTTTCTGAAAC
TGGATTTGGAAGATCCCAGCCTGGACTTGGACATTTTCATGAGTCAGGAAGTGTTGCCTGCTGC
CACCACCATCCTCTGAGTCCTTCCTCTGCCCTCCCCAACTACTTGAGACCCAGGGGCTGCAATG
TCTTTTTGGTTTTCTTATCTCCTTTAGACCCAGAGTTCTCAATTTCTGTAGAAATTTTGTTTCA
TGTTAGGAATAAAGTTTATTTTGGATAATGTTATTGTTTCCTTAGGCAATCCAAAACAGAACAG
GAGAATAGGACAGAGATGAAGCACCAAGCAGAATTCCACAGAGGAACCTGCCCTACCTCACTAA
AAGTACATTGACACTGCTATGGGAAGACCCTCAGATTCTTCCCCAGGAGACTTCTTGAGAAAAA
GCTACTTAAGAAAGGCCCTGTGAAAACAGAATAAAGAAATGAAAGAGGGGTCCAAGAGAGATGG
TTTTCCTCCTTATCTATGAATACCTCAGCCTTAGAGAGACACCACAGGAAGGGGCCAGAGAGGC
AGAATGGGTGTGAGGGAGGGGTAGAGGGGAGGGACCAGCTCAGGCCACAGCAGAGGGAGTGGCT
ACACCTTCCTCACCTCAGAGCCATGGGGAGCCAGGGTTCTGGTGGGCAGCCCCTGGCACAGGCT
CCCTACACAGTTCTGCTGCTGCCACTGGGAACAAGCCGAGAAGACCCTGGGGCCCAGAGCTTTT
TTCTTTGGCTGCAGAGGATGCAGGCTCTGGAGAGAGAGCAGGATGCCCTGTGGCAGGGCCTGGA
GCTGCTGGAACATGGCCGGGCCTGGTTTGAAGACCATCTGAGGGAGGCACAGCAACAGCAGCTG
CATCTGGGAGCCCTTGGTGAGAATTTTCTAACAGATTTACACTCAGAGCCTGGCGGCCCCCAGT
TAGCCCAAATT

hide sequence

RefSeq Acc Id:

XM_040282393 ⟹ XP_040138327

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	35,767,176 - 35,783,919 (+)	NCBI

RefSeq Acc Id:

XM_040282394 ⟹ XP_040138328

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	35,767,176 - 35,783,919 (+)	NCBI

RefSeq Acc Id:

XR_005732706

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	35,767,176 - 35,785,306 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_021591396	(Get FASTA)	NCBI Sequence Viewer
	XP_021591397	(Get FASTA)	NCBI Sequence Viewer
	XP_040138327	(Get FASTA)	NCBI Sequence Viewer
	XP_040138328	(Get FASTA)	NCBI Sequence Viewer
	XP_077876399	(Get FASTA)	NCBI Sequence Viewer
	XP_077876400	(Get FASTA)	NCBI Sequence Viewer
	XP_077876401	(Get FASTA)	NCBI Sequence Viewer
	XP_077876402	(Get FASTA)	NCBI Sequence Viewer
	XP_077876403	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000011727.3
GenBank Protein	KAG3289115	(Get FASTA)	NCBI Sequence Viewer
	KAG3289116	(Get FASTA)	NCBI Sequence Viewer
	KAG3289117	(Get FASTA)	NCBI Sequence Viewer
	KAG3289118	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021591397 ⟸ XM_021735722

- Peptide Label:

isoform X2

- Sequence:

show sequence

MTFQATPGRTPQGLGPGAASARFPNLVPAPGPAEANEEEDEEEEGPAEIHLCVLWNSGYLGIAY
YDTSDSIVHFMPDAPDHESLKLLQRVVDEINPRSVVTSAKQDENMTRFLGKLASQEHREPKRPE
IILLPSVDFGLEISKQRLLSGNYSFVPESMTATEKILFLSSIIPFDCLLTVRALGGLLKFLGRR
RIGVELEDYNVSIPILGFKKFVLTHLVSIDQDTYSVLQIFKSEAHPSVYKVASGLKEGLSLFGI
LNRCRCKWGEKLLRLWFTRPTQDLGELNSRLDVIQFFLLPQNLDMAQMLHRLMSHIKNVPLILK
RMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQEFSDDLHHIASLIGKVVDFE
GSLAENRFTVLPNVDPEIDEKKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSI
PRLPSMVEAGDFEIEGLDFMFLSEEKLHYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVL
ARAAVLTRVLDLASRLDALLALASAARDYGYSRPHYSPQLHGVRIHNGRHPLMELCARTFVPNS
AECGGDKGKVKVVTGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESI
SLGLSTFMIDLNQVAKAVNNATERSLVLIDEFGKGTNTVDGLALLAAVLRHWLVLGPMCPHIFV
ATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCGGVANASYASHTAAQAGLPEKLIA
RGKEISDLIRNGKPIKPVKELLKENQMQNCQTLVDKFLKLDLEDPSLDLDIFMSQEVLPAATTI
L

hide sequence

RefSeq Acc Id:

XP_021591396 ⟸ XM_021735721

- Peptide Label:

isoform X1

- Sequence:

show sequence

MTFQATPGRTPQGLGPGAASARFPNLVPAPGPAEANEEEDEEEEGPAEIHLCVLWNSGYLGIAY
YDTSDSIVHFMPDAPDHESLKLLQRVVDEINPRSVVTSAKQDENMTRFLGKLASQEHREPKRPE
IILLPSVDFGLEISKQRLLSGNYSFVPESMTATEKILFLSSIIPFDCLLTVRALGGLLKFLGRR
RIGVELEDYNVSIPILGFKKFVLTHLVSIDQDTYSVLQIFKSEAHPSVYKVASGLKEGLSLFGI
LNRCRCKWGEKLLRLWFTRPTQDLGELNSRLDVIQFFLLPQNLDMAQMLHRLMSHIKNVPLILK
RMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQEFSDDLHHIASLIGKVVDFE
GSLAENRFTVLPNVDPEIDEKKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSI
PRLPSMVEAGDFEIEGLDFMFLSEEKLHYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVL
ARAAVLTRVLDLASRLDALLALASAARDYGYSRPHYSPQLHGVRIHNGRHPLMELCARTFVPNS
AECGGDKGKVKVVTGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESI
SLGLSTFMIDLNQQVAKAVNNATERSLVLIDEFGKGTNTVDGLALLAAVLRHWLVLGPMCPHIF
VATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCGGVANASYASHTAAQAGLPEKLI
ARGKEISDLIRNGKPIKPVKELLKENQMQNCQTLVDKFLKLDLEDPSLDLDIFMSQEVLPAATT
IL

hide sequence

RefSeq Acc Id:	XP_040138328 ⟸ XM_040282394
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_040138327 ⟸ XM_040282393
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSSTOP00000011727 ⟸ ENSSTOT00000013085

Protein Domains

DNA mismatch repair proteins mutS family

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000013079	Ensembl, UniProtKB/TrEMBL
	ENSSTOG00015020669	ENTREZGENE
Ensembl Transcript	ENSSTOT00000013085.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1420.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	DNA_mismatch_repair_MutS/MSH	UniProtKB/TrEMBL
	DNA_mismatch_repair_MutS_C	UniProtKB/TrEMBL
	DNA_mismatch_repair_MutS_clamp	UniProtKB/TrEMBL
	DNA_mismatch_repair_MutS_core	UniProtKB/TrEMBL
	DNA_mismatch_repair_MutS_sf	UniProtKB/TrEMBL
	MutS_family	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
NCBI Gene	Msh5	ENTREZGENE
PANTHER	MUTS PROTEIN HOMOLOG 5	UniProtKB/TrEMBL
	PTHR11361	UniProtKB/TrEMBL
Pfam	MutS_III	UniProtKB/TrEMBL
	MutS_IV	UniProtKB/TrEMBL
	MutS_V	UniProtKB/TrEMBL
PIRSF	DNA_mis_repair_Msh6	UniProtKB/TrEMBL
PROSITE	DNA_MISMATCH_REPAIR_2	UniProtKB/TrEMBL
SMART	MUTSac	UniProtKB/TrEMBL
	MUTSd	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48334	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	I3MKC5_ICTTR	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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