Acer3 (alkaline ceramidase 3) - Rat Genome Database

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Gene: Acer3 (alkaline ceramidase 3) Ictidomys tridecemlineatus
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Symbol: Acer3
Name: alkaline ceramidase 3
RGD ID: 12599312
Description: ENCODES a protein that exhibits calcium ion binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN ceramide catabolic process (inferred); ceramide metabolic process (inferred); inflammatory response (inferred); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; ASSOCIATED WITH colon cancer (ortholog); Experimental Colitis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); Golgi membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494763,891,661 - 64,079,838 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364985,496,991 - 5,653,206 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364985,496,991 - 5,653,206 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Acer3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494763,891,661 - 64,079,838 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364985,496,991 - 5,653,206 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364985,496,991 - 5,653,206 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACER3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381176,860,918 - 77,026,797 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1176,860,859 - 77,026,797 (+)Ensemblhg38GRCh38
GRCh371176,571,962 - 76,737,841 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361176,249,601 - 76,411,617 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341176,249,600 - 76,411,615NCBI
Celera1173,879,386 - 74,042,342 (+)NCBICelera
Cytogenetic Map11q13.5NCBI
HuRef1172,869,413 - 73,032,747 (+)NCBIHuRef
CHM1_11176,454,989 - 76,617,931 (+)NCBICHM1_1
T2T-CHM13v2.01176,791,211 - 76,957,150 (+)NCBIT2T-CHM13v2.0
Acer3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39797,863,015 - 97,970,415 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl797,855,596 - 97,970,415 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38798,213,808 - 98,321,208 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl798,206,389 - 98,321,208 (-)Ensemblmm10GRCm38
MGSCv377105,362,170 - 105,458,037 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36798,088,852 - 98,184,719 (-)NCBIMGSCv36mm8
Celera798,537,783 - 98,626,816 (-)NCBICelera
Cytogenetic Map7E1NCBI
cM Map753.65NCBI
Acer3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81161,915,397 - 162,017,802 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1161,915,397 - 162,017,912 (-)EnsemblGRCr8
mRatBN7.21152,504,180 - 152,606,596 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1152,504,186 - 152,606,591 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1160,491,517 - 160,594,641 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01167,671,695 - 167,774,816 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01160,545,214 - 160,648,336 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1160,891,552 - 160,993,832 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1165,880,754 - 165,983,028 (-)NCBILyon_Normotensive
Lyon_Hypertensive1162,521,177 - 162,623,556 (-)NCBILyon_Hypertensive
F344_StmMcwi1161,110,248 - 161,212,549 (-)NCBIF344_StmMcwi
Rnor_6.01163,160,987 - 163,263,621 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1163,160,979 - 163,263,606 (-)Ensemblrn6Rnor6.0
Rnor_5.01169,367,775 - 169,469,576 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41155,455,466 - 155,556,319 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1150,595,013 - 150,696,477 (-)NCBICelera
Cytogenetic Map1q32NCBI
Acer3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541414,746,529 - 14,848,151 (-)Ensembl
ChiLan1.0NW_00495541414,741,027 - 14,846,931 (-)NCBIChiLan1.0ChiLan1.0
ACER3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2977,780,518 - 77,946,567 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11178,827,701 - 78,994,744 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01171,911,204 - 72,077,528 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11175,557,846 - 75,717,627 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1175,557,846 - 75,717,586 (+)EnsemblpanPan2panpan1.1
ACER3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12121,711,315 - 21,863,409 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2121,714,156 - 21,863,320 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2121,541,041 - 21,692,389 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02121,911,015 - 22,065,639 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2121,908,919 - 22,065,649 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12121,686,424 - 21,836,835 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02121,904,895 - 22,056,205 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02121,826,685 - 21,978,077 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
ACER3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl910,967,857 - 11,162,502 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1910,985,078 - 11,167,386 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2912,135,522 - 12,190,445 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACER3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1168,072,323 - 68,228,036 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl168,072,544 - 68,227,736 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604357,546,989 - 57,716,409 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acer3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462486337,148 - 95,211 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462486337,148 - 96,550 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Acer3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1296,492,627 - 96,581,272 (-)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000002667   ⟹   ENSSTOP00000002387
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364985,496,991 - 5,653,206 (+)Ensembl
RefSeq Acc Id: XM_040284977   ⟹   XP_040140911
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494763,897,394 - 64,079,830 (+)NCBI
RefSeq Acc Id: XM_040284978   ⟹   XP_040140912
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494763,897,394 - 64,079,838 (+)NCBI
RefSeq Acc Id: XM_040284979   ⟹   XP_040140913
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494763,897,388 - 64,079,833 (+)NCBI
RefSeq Acc Id: XM_040284980   ⟹   XP_040140914
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494763,891,661 - 64,079,833 (+)NCBI
RefSeq Acc Id: XP_040140914   ⟸   XM_040284980
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040140913   ⟸   XM_040284979
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040140912   ⟸   XM_040284978
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040140911   ⟸   XM_040284977
- Peptide Label: isoform X1
Ensembl Acc Id: ENSSTOP00000002387   ⟸   ENSSTOT00000002667


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002656 Ensembl, UniProtKB/TrEMBL
  ENSSTOG00015009014 ENTREZGENE
Ensembl Transcript ENSSTOT00000002667.3 UniProtKB/TrEMBL
InterPro ACER UniProtKB/TrEMBL
NCBI Gene Acer3 ENTREZGENE
PANTHER ALKALINE CERAMIDASE 3 UniProtKB/TrEMBL
  PTHR46187 UniProtKB/TrEMBL
Pfam Ceramidase UniProtKB/TrEMBL
UniProt I3M0V5_ICTTR UniProtKB/TrEMBL