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Gene: Gpr139 (G protein-coupled receptor 139) Ictidomys tridecemlineatus

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Symbol:

Gpr139

Name:

G protein-coupled receptor 139

RGD ID:

12491498

Description:

ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); identical protein binding (inferred); neuropeptide receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathway (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

probable G-protein coupled receptor 139; putative G-protein coupled receptor 139

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	117,484,457 - 117,523,430 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	5,585,798 - 5,620,385 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	5,585,278 - 5,620,667 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IEA,ISO)

neuropeptide signaling pathway (IEA)

phospholipase C-activating G protein-coupled receptor signaling pathway (IEA,ISO)

signal transduction (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

identical protein binding (IEA)

neuropeptide receptor activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Gpr139
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	117,484,457 - 117,523,430 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	5,585,798 - 5,620,385 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	5,585,278 - 5,620,667 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR139
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	20,028,239 - 20,073,890 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	20,028,239 - 20,073,890 (-)	Ensembl			hg38	GRCh38
GRCh37	16	20,039,561 - 20,085,212 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	19,950,544 - 19,992,601 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	16	19,191,989 - 19,234,374 (-)	NCBI		Celera
Cytogenetic Map	16	p12.3	NCBI
HuRef	16	18,579,949 - 18,622,260 (-)	NCBI		HuRef
CHM1_1	16	20,130,377 - 20,172,340 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	19,959,033 - 20,004,824 (-)	NCBI		T2T-CHM13v2.0

Gpr139
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	118,739,970 - 118,783,761 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	118,739,970 - 118,783,826 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	119,140,747 - 119,184,538 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	119,140,747 - 119,184,603 (-)	Ensembl			mm10	GRCm38
MGSCv37	7	126,287,837 - 126,327,888 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	118,935,472 - 118,975,523 (-)	NCBI		MGSCv36	mm8
Celera	7	119,078,265 - 119,118,422 (-)	NCBI		Celera
Cytogenetic Map	7	F2	NCBI
cM Map	7	63.79	NCBI

Gpr139
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	182,909,476 - 182,953,942 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	182,909,476 - 182,953,942 (-)	Ensembl				GRCr8
mRatBN7.2	1	173,478,137 - 173,522,615 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	173,481,583 - 173,522,451 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	181,788,720 - 181,830,189 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	188,974,824 - 189,016,299 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	181,712,576 - 181,754,036 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	1	182,155,788 - 182,200,238 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	1	187,183,619 - 187,228,069 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	1	183,851,045 - 183,895,495 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	1	182,128,604 - 182,173,014 (-)	NCBI		F344_StmMcwi
Rnor_6.0	1	188,854,371 - 188,895,223 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	188,854,371 - 188,895,223 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	195,796,295 - 195,837,147 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	177,373,619 - 177,415,129 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	171,242,774 - 171,283,487 (-)	NCBI		Celera
RGSC_v3.1	1	177,512,865 - 177,554,375 (-)	NCBI
Cytogenetic Map	1	q35	NCBI

Gpr139
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	3,698,546 - 3,737,281 (-)	Ensembl
ChiLan1.0	NW_004955442	3,698,546 - 3,737,281 (-)	NCBI	ChiLan1.0	ChiLan1.0

GPR139
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	21,292,449 - 21,338,084 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	25,814,157 - 25,859,790 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	18,238,117 - 18,283,773 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	20,130,146 - 20,172,342 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	20,126,515 - 20,172,343 (-)	Ensembl			panPan2	panpan1.1

GPR139
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	25,249,898 - 25,293,044 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	25,249,584 - 25,290,435 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	26,612,629 - 26,652,957 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	25,404,038 - 25,444,386 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	25,403,784 - 25,444,360 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	25,204,794 - 25,245,139 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	25,100,135 - 25,140,480 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	25,487,861 - 25,528,008 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

GPR139
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	25,714,298 - 25,757,504 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	25,714,321 - 25,760,574 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	26,493,397 - 26,539,596 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPR139
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	18,323,427 - 18,367,528 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	18,325,071 - 18,366,841 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666068	11,549,085 - 11,593,444 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpr139
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	3,362,869 - 3,402,880 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624782	3,360,589 - 3,403,112 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gpr139
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	82,470,247 - 82,510,687 (+)	NCBI		Rrattus_CSIRO_v1

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005323715	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277577	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JBPVTT010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000004911 ⟹ ENSSTOP00000004405

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936501	5,585,798 - 5,620,385 (-)	Ensembl

RefSeq Acc Id:

XM_005323715 ⟹ XP_005323772

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	117,484,457 - 117,522,996 (-)	NCBI
SpeTri2.0	NW_004936501	5,585,278 - 5,620,667 (-)	NCBI

Sequence:

show sequence

GAGCGGTCCGAGGTGGGAGGTGCACTAACCGGCTCCGAGCCCCTCCCGAGTCCCCGCGCCCTGC
GCCGCGCGCTCTGCACCCTGTGGGAGGGCTGAGCGCGGACTCCAGGCGGGCAGGTGCGGAGCGA
GCAGAGGATCGCGGCCAAGGGTAGAAGCCAGTCCTGCGGGGAGAGAGGCGCCGCTGCTCCAGCT
GCTGCCTCCGCCGCCACCACCACGGAGCCGGCGTCCAGAGCCCGGCTGGCAGGCTGGGCGCGCA
GCGGCGAGGGCAGGAGGGGCGCGCTCATGGAGCACACGCACGCCCACCTCGCAGCCAACAGCTC
GCTGTCCTGCGGCTTGGGCTTCGTGCCCGTGGTCTACTACAGCCTCCTGCTGTGCCTCGGTTTA
CCAGCAAACATCTTGACGGTGATCATCCTCTCGCAGCTGGTGGCCAGACGGCAGAAGTCCTCCT
ACAACTATCTCTTGGCGCTGGCCGCGGCCGACATCCTGGTCCTCTTCTTCATCGTGTTTGTCGA
CTTCCTGTTGGAAGACTTCATCCTGCACATGCAGATGCCCCAGGTCCCCGACAAGATCATCGAA
GTCCTGGAGTTCACCTCCATCCACACCTCCATCTGGATCACGGTTCCCTTGACCATCGACAGGT
ACATCGCCGTCTGCCACCCGCTCAAATACCACACCGTCTCCTACCCGGCCCGCACCCGGAAGGT
CATTGTCAGCGTTTACGTCACCTGCTTCCTGACCAGCATCCCCTACTACTGGTGGCCCAACATC
TGGACCGAGGACTACATCAGCACCTCCGTGCACCACATCCTGGTGTGGGTACACTGCTTCACCG
TGTACCTGGTGCCCTGCTCCATCTTCTTCATCTTGAACTCCATCATCGTGTACAAGCTCAGGAG
GAAGAGCAACTTTCGCCTCCGTGGCTACTCCACTGGGAAGACCACCGCCATCTTGTTCACCATC
ACCTCCATCTTCGCCACGCTCTGGGCCCCCCGCATCATCGTGATCCTCTACCACCTCTACGGGA
CGCCCATCCAGAACCTCTGGCTGGTGCACATCATGTCCGACGTGGCCAACATGCTGGCCCTCCT
GAACACGGCCATCAACTTCTTCCTTTACTGCTTCATCAGCAAGCGGTTCCGAACCATGGCGGCC
GCCACGCTCAAGGCCTTCTTCAAGTGCCAGAAGCAGCCTGTGCAGTTCTACACCAACCATAACT
TTTCCATAACGAGTAGTCCCTGGATCTCGCCGGCCAACTCCCACTGTATCAAGATGCTGGTATA
CCAGTACGACAAAAACGGAAAGCCTATAAAAGTCTCCCCTTGACACCCCCCTGGGTTGGCACCG
AGTGCCTCGTGTGTGATCCATTCCCGATGGGAGGGCGTCCCATCCTCTGGCTGAACAGGTCTCC
TTAAGAGTGCTAACCTGATTTCCTGCCTCCACAGACTGAGGAACTCTCAGGGTGGCAGATGAGA
GAGAGACGGAAGAGAAGAAGAAAGGAAAGCATGAATCTCGTTTTTCCTGTGTGCACTCATTTCC
ACAAAAATAAAATCACGTCGACAGCAAAAGTTCCTACCCGTTTGGAGATGCTGTTGGAAGTTGT
GCCATCATCCTGTGACCAGTGAGGACCACAGTAGAGAAATAGTCTGTGATTTAGCACCGGCACC
ATCCACCATCACTGGGAACCACTCATTTGTGTGACACCCCGAGCCATGGTAGCGCGTGGCCACG
TCGAAGCTCTTCTTCCCAGAGCTGAGGTCATCCATCGCTCCCCTGGGCCATGCCCAGAAGGCTA
CCCATGCTGACTGATGGGAGATTTTTTTCCAAGGTGCCCTCTGTCCTAGAGAG

hide sequence

RefSeq Acc Id:

XM_040277576 ⟹ XP_040133510

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	117,484,457 - 117,523,430 (-)	NCBI

RefSeq Acc Id:

XM_040277577 ⟹ XP_040133511

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	117,484,457 - 117,504,416 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005323772	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000004405.3
GenBank Protein	KAG3259427	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005323772 ⟸ XM_005323715
- Peptide Label:	isoform X2
- UniProtKB:	I3M538 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEHTHAHLAANSSLSCGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAA ADILVLFFIVFVDFLLEDFILHMQMPQVPDKIIEVLEFTSIHTSIWITVPLTIDRYIAVCHPLK YHTVSYPARTRKVIVSVYVTCFLTSIPYYWWPNIWTEDYISTSVHHILVWVHCFTVYLVPCSIF FILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIVILYHLYGTPIQNLWLV HIMSDVANMLALLNTAINFFLYCFISKRFRTMAAATLKAFFKCQKQPVQFYTNHNFSITSSPWI SPANSHCIKMLVYQYDKNGKPIKVSP hide sequence

RefSeq Acc Id:	XP_040133510 ⟸ XM_040277576
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_040133511 ⟸ XM_040277577
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSSTOP00000004405 ⟸ ENSSTOT00000004911

Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000004919	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000004911.3	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	GPR139	UniProtKB/TrEMBL
	Orphan_GPCR1	UniProtKB/TrEMBL
KEGG Report	iti:101968615	UniProtKB/TrEMBL
NCBI Gene	Gpr139	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR 139-RELATED	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	I3M538	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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