GPR139 (G protein-coupled receptor 139) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: GPR139 (G protein-coupled receptor 139) Sus scrofa
Analyze
Symbol: GPR139
Name: G protein-coupled receptor 139
RGD ID: 14122692
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); identical protein binding (inferred); neuropeptide receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable G-protein coupled receptor 139
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl325,714,298 - 25,757,504 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1325,714,321 - 25,760,574 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2326,493,397 - 26,539,596 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
GPR139
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl325,714,298 - 25,757,504 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1325,714,321 - 25,760,574 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2326,493,397 - 26,539,596 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPR139
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381620,028,239 - 20,073,890 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1620,028,239 - 20,073,890 (-)EnsemblGRCh38hg38GRCh38
GRCh371620,039,561 - 20,085,212 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361619,950,544 - 19,992,601 (-)NCBINCBI36Build 36hg18NCBI36
Celera1619,191,989 - 19,234,374 (-)NCBICelera
Cytogenetic Map16p12.3NCBI
HuRef1618,579,949 - 18,622,260 (-)NCBIHuRef
CHM1_11620,130,377 - 20,172,340 (-)NCBICHM1_1
T2T-CHM13v2.01619,959,033 - 20,004,824 (-)NCBIT2T-CHM13v2.0
Gpr139
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397118,739,970 - 118,783,761 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7118,739,970 - 118,783,826 (-)EnsemblGRCm39 Ensembl
GRCm387119,140,747 - 119,184,538 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7119,140,747 - 119,184,603 (-)EnsemblGRCm38mm10GRCm38
MGSCv377126,287,837 - 126,327,888 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367118,935,472 - 118,975,523 (-)NCBIMGSCv36mm8
Celera7119,078,265 - 119,118,422 (-)NCBICelera
Cytogenetic Map7F2NCBI
cM Map763.79NCBI
Gpr139
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81182,909,476 - 182,953,942 (-)NCBIGRCr8
mRatBN7.21173,478,137 - 173,522,615 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1173,481,583 - 173,522,451 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1181,788,720 - 181,830,189 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01188,974,824 - 189,016,299 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01181,712,576 - 181,754,036 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01188,854,371 - 188,895,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,854,371 - 188,895,223 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01195,796,295 - 195,837,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41177,373,619 - 177,415,129 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11177,512,865 - 177,554,375 (-)NCBI
Celera1171,242,774 - 171,283,487 (-)NCBICelera
Cytogenetic Map1q35NCBI
Gpr139
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554423,698,546 - 3,737,281 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554423,698,546 - 3,737,281 (-)NCBIChiLan1.0ChiLan1.0
GPR139
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21821,292,449 - 21,338,084 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11625,814,157 - 25,859,790 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01618,238,117 - 18,283,773 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11620,130,146 - 20,172,342 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1620,126,515 - 20,172,343 (-)Ensemblpanpan1.1panPan2
GPR139
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1625,249,898 - 25,293,044 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl625,249,584 - 25,290,435 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha626,612,629 - 26,652,957 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0625,404,038 - 25,444,386 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl625,403,784 - 25,444,360 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1625,204,794 - 25,245,139 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0625,100,135 - 25,140,480 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0625,487,861 - 25,528,008 (+)NCBIUU_Cfam_GSD_1.0
Gpr139
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344117,484,457 - 117,523,430 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365015,585,798 - 5,620,385 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365015,585,278 - 5,620,667 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPR139
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1518,323,427 - 18,367,528 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl518,325,071 - 18,366,841 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606811,549,085 - 11,593,444 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpr139
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247823,362,869 - 3,402,880 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247823,360,589 - 3,403,112 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GPR139
1655 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

nervous system
High
Medium
Low 6
Below cutoff 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000008614   ⟹   ENSSSCP00000008393
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl325,714,298 - 25,757,504 (+)Ensembl
RefSeq Acc Id: XM_003124564   ⟹   XP_003124612
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1325,714,321 - 25,760,574 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003124612   ⟸   XM_003124564
- UniProtKB: F1RPA5 (UniProtKB/TrEMBL),   A0A8D0YZE3 (UniProtKB/TrEMBL),   A0A4X1VHJ8 (UniProtKB/TrEMBL),   A0A8D1HM46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000008393   ⟸   ENSSSCT00000008614
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007862 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025072705 UniProtKB/TrEMBL
  ENSSSCG00030018420 UniProtKB/TrEMBL
  ENSSSCG00035016632 UniProtKB/TrEMBL
  ENSSSCG00040075525 UniProtKB/TrEMBL
  ENSSSCG00045017289 UniProtKB/TrEMBL
  ENSSSCG00050048871 UniProtKB/TrEMBL
  ENSSSCG00055012883 UniProtKB/TrEMBL
  ENSSSCG00060062199 UniProtKB/TrEMBL
  ENSSSCG00065073765 UniProtKB/TrEMBL
  ENSSSCG00070024517 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000008614 ENTREZGENE
  ENSSSCT00000008614.5 UniProtKB/TrEMBL
  ENSSSCT00025100005.1 UniProtKB/TrEMBL
  ENSSSCT00030025426.1 UniProtKB/TrEMBL
  ENSSSCT00035021272.1 UniProtKB/TrEMBL
  ENSSSCT00040104789.1 UniProtKB/TrEMBL
  ENSSSCT00045029403.1 UniProtKB/TrEMBL
  ENSSSCT00050066518.1 UniProtKB/TrEMBL
  ENSSSCT00055025351.1 UniProtKB/TrEMBL
  ENSSSCT00060084838.1 UniProtKB/TrEMBL
  ENSSSCT00065101553.1 UniProtKB/TrEMBL
  ENSSSCT00070048927.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  GPR139 UniProtKB/TrEMBL
KEGG Report ssc:100511500 UniProtKB/TrEMBL
NCBI Gene GPR139 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR 139-RELATED UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A4X1VHJ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YZE3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1HM46 ENTREZGENE, UniProtKB/TrEMBL
  F1RPA5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:88603 ENTREZGENE