PGC (progastricsin) - Rat Genome Database

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Gene: PGC (progastricsin) Canis lupus familiaris
Analyze
Symbol: PGC
Name: progastricsin
RGD ID: 12350437
Description: ENCODES a protein that exhibits aspartic-type endopeptidase activity (ortholog); INVOLVED IN positive regulation of antibacterial peptide production (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: gastricsin; progastricsin (pepsinogen C)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11210,425,137 - 10,435,129 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1210,454,837 - 10,463,787 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01210,905,543 - 10,914,475 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11210,436,269 - 10,445,194 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01210,519,705 - 10,528,842 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01210,613,396 - 10,622,545 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PGC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11210,425,137 - 10,435,129 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1210,454,837 - 10,463,787 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01210,905,543 - 10,914,475 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11210,436,269 - 10,445,194 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01210,519,705 - 10,528,842 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01210,613,396 - 10,622,545 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
PGC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38641,736,711 - 41,747,397 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl641,736,711 - 41,754,109 (-)Ensemblhg38GRCh38
GRCh37641,704,449 - 41,715,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36641,812,430 - 41,823,099 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34641,812,429 - 41,823,099NCBI
Celera643,257,886 - 43,268,464 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef641,423,279 - 41,433,946 (-)NCBIHuRef
CHM1_1641,707,932 - 41,718,508 (-)NCBICHM1_1
T2T-CHM13v2.0641,565,267 - 41,576,000 (-)NCBIT2T-CHM13v2.0
Pgc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391748,037,767 - 48,045,403 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1748,037,767 - 48,045,407 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381747,726,842 - 47,734,478 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1747,726,842 - 47,734,482 (+)Ensemblmm10GRCm38
MGSCv371747,863,791 - 47,871,427 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361747,190,033 - 47,197,669 (+)NCBIMGSCv36mm8
Celera1751,163,923 - 51,171,529 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1723.98NCBI
Pgc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8920,755,002 - 20,763,220 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl920,755,002 - 20,763,220 (-)EnsemblGRCr8
mRatBN7.2913,257,462 - 13,265,682 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl913,257,462 - 13,265,682 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx921,837,988 - 21,845,673 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0926,902,067 - 26,909,766 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0925,201,385 - 25,209,079 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd924,603,529 - 24,611,228 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive920,381,503 - 20,389,202 (-)NCBILyon_Normotensive
Lyon_Hypertensive920,471,244 - 20,478,939 (-)NCBILyon_Hypertensive
F344_StmMcwi922,423,174 - 22,430,861 (-)NCBIF344_StmMcwi
Rnor_6.0915,266,699 - 15,274,917 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl915,266,699 - 15,274,917 (-)Ensemblrn6Rnor6.0
Rnor_5.0914,191,145 - 14,199,127 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.498,723,620 - 8,731,837 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera911,009,766 - 11,018,396 (-)NCBICelera
RGSC_v3.198,722,923 - 8,731,141 (-)NCBI
Cytogenetic Map9q12NCBI
Pgc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554378,142,661 - 8,151,339 (-)Ensembl
ChiLan1.0NW_0049554378,142,523 - 8,153,044 (-)NCBIChiLan1.0ChiLan1.0
PGC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2556,229,793 - 56,240,297 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1652,099,801 - 52,110,296 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0641,321,932 - 41,330,494 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1642,627,385 - 42,637,514 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl642,627,222 - 42,637,514 (-)EnsemblpanPan2panpan1.1
Pgc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494645,913,605 - 45,920,575 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647618,039,709 - 18,046,510 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647618,039,709 - 18,046,510 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl736,922,271 - 36,951,349 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1736,922,269 - 36,951,380 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2742,257,163 - 42,286,645 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PGC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11730,414,769 - 30,424,708 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1730,415,124 - 30,424,766 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604441,732,945 - 41,743,040 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475417,311,644 - 17,319,764 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475417,311,743 - 17,319,675 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pgc
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1482,142,680 - 82,150,222 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in PGC
172 total Variants

Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_038492733   ⟹   XP_038348661
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11210,436,269 - 10,445,194 (-)NCBI
RefSeq Acc Id: XM_038553373   ⟹   XP_038409301
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01210,613,396 - 10,622,545 (-)NCBI
RefSeq Acc Id: XM_038617267   ⟹   XP_038473195
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01210,519,705 - 10,528,842 (-)NCBI
RefSeq Acc Id: XM_038677358   ⟹   XP_038533286
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1210,454,837 - 10,463,787 (-)NCBI
RefSeq Acc Id: XM_038682846   ⟹   XP_038538774
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01210,905,543 - 10,914,475 (-)NCBI
RefSeq Acc Id: XP_038348661   ⟸   XM_038492733
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038473195   ⟸   XM_038617267
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038538774   ⟸   XM_038682846
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038533286   ⟸   XM_038677358
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038409301   ⟸   XM_038553373
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
NCBI Gene PGC ENTREZGENE
VGNC ID VGNC:57228 ENTREZGENE