NRIP2 (nuclear receptor interacting protein 2) - Rat Genome Database

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Pathways
Gene: NRIP2 (nuclear receptor interacting protein 2) Canis lupus familiaris
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Symbol: NRIP2
Name: nuclear receptor interacting protein 2
RGD ID: 12062004
Description: ENCODES a protein that exhibits aspartic-type endopeptidase activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); Notch signaling pathway (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear receptor-interacting protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12741,925,083 - 41,933,475 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2741,925,730 - 41,931,669 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha274,750,712 - 4,758,746 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02742,283,595 - 42,291,630 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2742,283,691 - 42,291,627 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12742,225,122 - 42,233,152 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02742,194,799 - 42,202,824 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0274,110,419 - 4,118,454 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
NRIP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12741,925,083 - 41,933,475 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2741,925,730 - 41,931,669 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha274,750,712 - 4,758,746 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02742,283,595 - 42,291,630 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2742,283,691 - 42,291,627 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12742,225,122 - 42,233,152 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02742,194,799 - 42,202,824 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0274,110,419 - 4,118,454 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
NRIP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38122,825,348 - 2,835,035 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl122,825,348 - 2,835,544 (-)Ensemblhg38GRCh38
GRCh37122,934,514 - 2,944,201 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,804,775 - 2,814,450 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34122,804,775 - 2,814,450NCBI
Celera124,548,450 - 4,558,161 (-)NCBICelera
Cytogenetic Map12p13.33NCBI
HuRef122,792,079 - 2,801,789 (-)NCBIHuRef
CHM1_1122,933,751 - 2,943,458 (-)NCBICHM1_1
T2T-CHM13v2.0122,831,348 - 2,841,035 (-)NCBIT2T-CHM13v2.0
Nrip2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396128,374,780 - 128,386,747 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6128,376,259 - 128,393,390 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm386128,397,818 - 128,409,780 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6128,399,296 - 128,416,427 (+)Ensemblmm10GRCm38
MGSCv376128,349,784 - 128,358,953 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366128,365,385 - 128,373,870 (+)NCBIMGSCv36mm8
Celera6130,076,598 - 130,085,769 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map662.99NCBI
Nrip2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84163,359,592 - 163,370,144 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4163,360,665 - 163,370,141 (+)EnsemblGRCr8
mRatBN7.24161,673,964 - 161,684,055 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4161,639,356 - 161,684,070 (+)EnsemblmRatBN7.2
Dahl_SR_JrHsd4165,524,414 - 165,533,708 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive4163,181,123 - 163,190,417 (+)NCBILyon_Normotensive
Lyon_Hypertensive4163,664,190 - 163,673,484 (+)NCBILyon_Hypertensive
F344_StmMcwi4162,998,022 - 163,007,316 (+)NCBIF344_StmMcwi
Rnor_6.04161,719,434 - 161,729,673 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4161,720,501 - 161,729,192 (+)Ensemblrn6Rnor6.0
Rnor_5.04226,924,969 - 226,935,214 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44165,419,535 - 165,427,882 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4150,375,415 - 150,385,654 (+)NCBICelera
Cytogenetic Map4q42NCBI
NRIP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2108,377,177 - 8,385,257 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1128,372,124 - 8,382,447 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0122,945,844 - 2,956,155 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1122,877,833 - 2,888,177 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl122,879,690 - 2,887,722 (-)EnsemblpanPan2panpan1.1
Nrip2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945106,002,501 - 106,025,116 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366063,158,910 - 3,167,578 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366063,159,049 - 3,167,629 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NRIP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl567,281,107 - 67,291,522 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1567,281,032 - 67,291,524 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2569,567,779 - 69,577,827 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NRIP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,892,520 - 2,902,377 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,893,730 - 2,901,495 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660635,411,390 - 5,423,425 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in NRIP2
63 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000024801   ⟹   ENSCAFP00000023008
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2741,925,730 - 41,931,669 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845044339   ⟹   ENSCAFP00845034743
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2742,283,691 - 42,291,627 (+)Ensembl
RefSeq Acc Id: XM_038439332   ⟹   XP_038295260
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02742,283,595 - 42,291,630 (+)NCBI
RefSeq Acc Id: XM_038513991   ⟹   XP_038369919
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12742,225,122 - 42,233,152 (+)NCBI
RefSeq Acc Id: XM_038576463   ⟹   XP_038432391
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0274,110,419 - 4,118,454 (-)NCBI
RefSeq Acc Id: XM_038641845   ⟹   XP_038497773
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02742,194,799 - 42,202,824 (+)NCBI
RefSeq Acc Id: XM_543871   ⟹   XP_543871
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12741,925,083 - 41,933,475 (+)NCBI
Dog10K_Boxer_Tasha274,750,712 - 4,758,746 (-)NCBI
Sequence:
RefSeq Acc Id: XP_543871   ⟸   XM_543871
- UniProtKB: A0A8C0KP72 (UniProtKB/TrEMBL),   A0A8C0TSG9 (UniProtKB/TrEMBL),   A0A8I3PXK9 (UniProtKB/TrEMBL),   A0A8C0PYH9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000023008   ⟸   ENSCAFT00000024801
RefSeq Acc Id: XP_038369919   ⟸   XM_038513991
RefSeq Acc Id: XP_038497773   ⟸   XM_038641845
RefSeq Acc Id: XP_038295260   ⟸   XM_038439332
- UniProtKB: A0A8C0KP72 (UniProtKB/TrEMBL),   A0A8C0TSG9 (UniProtKB/TrEMBL),   A0A8I3PXK9 (UniProtKB/TrEMBL),   A0A8C0PYH9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038432391   ⟸   XM_038576463
- UniProtKB: A0A8C0KP72 (UniProtKB/TrEMBL),   A0A8C0PYH9 (UniProtKB/TrEMBL),   A0A8C0TSG9 (UniProtKB/TrEMBL),   A0A8I3PXK9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845034743   ⟸   ENSCAFT00845044339

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015655 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025902 UniProtKB/TrEMBL
  ENSCAFG00040024400 UniProtKB/TrEMBL
  ENSCAFG00845025130 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000024801.5 UniProtKB/TrEMBL
  ENSCAFT00030047834.1 UniProtKB/TrEMBL
  ENSCAFT00040045453.1 UniProtKB/TrEMBL
  ENSCAFT00845044339 ENTREZGENE
  ENSCAFT00845044339.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.70.10 UniProtKB/TrEMBL
InterPro Peptidase_aspartic_DDI1-type UniProtKB/TrEMBL
  Peptidase_aspartic_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:486744 UniProtKB/TrEMBL
NCBI Gene NRIP2 ENTREZGENE
PANTHER ASPARTYL PROTEASE DDI-RELATED UniProtKB/TrEMBL
  NUCLEAR RECEPTOR-INTERACTING PROTEIN 2 UniProtKB/TrEMBL
Pfam Asp_protease UniProtKB/TrEMBL
Superfamily-SCOP SSF50630 UniProtKB/TrEMBL
UniProt A0A8C0KP72 ENTREZGENE
  A0A8C0PYH9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TSG9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PXK9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43970 ENTREZGENE