| 12587290 | Osm | oncostatin M | ENCODES a protein that exhibits growth factor activity (ortholog); INVOLVED IN behavioral response to pain (ortholog); negative regulation of hormone secretion (ortholog); negative regulation of meiotic nuclear division (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor sig naling pathway; interleukin-3 signaling pathway; ASSOCIATED WITH Chloracne (ortholog); contact dermatitis (ortholog); COVID-19 (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | NW_004936904 | 390089 | 394195 | Squirrel | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12448278 | Osmr | oncostatin M receptor | ENCODES a protein that exhibits cytokine binding (ortholog); oncostatin-M receptor activity (ortholog); INVOLVED IN oncostatin-M-mediated signaling pathway (inferred); positive regulation of cell population proliferation (inferred); response to cytokine (inferred); ASSOCIATED WITH COVID-19 (ortholog ); genetic disease (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN external side of plasma membrane (ortholog) | NW_004936518 | 3320057 | 3381518 | Squirrel | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12533320 | Tsc22d2 | TSC22 domain family member 2 | INVOLVED IN response to osmotic stress (ortholog); ASSOCIATED WITH keratoconus (ortholog) | NW_004936758 | 845359 | 898937 | Squirrel | 7 | description | gene, protein-coding, MODEL [RefSeq] |
| 12723494 | Dysf | dysferlin | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); microtubule binding (ortholog); INVOLVED IN angiogenesis (ortholog); cellular response to osmotic stress (ortholog); fat cell differentiation (ortholog); ASSOCIATED WITH autosomal recessive limb-g irdle muscular dystrophy (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2B (ortholog); autosomal recessive nonsyndromic deafness (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog); lamellipodium (ortholog) | NW_004936491 | 15412606 | 15618519 | Squirrel | 105 | description | gene, protein-coding, MODEL [RefSeq] |
| 125021944 | Gypa | glycophorin A (MNS blood group) | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN regulation of response to osmotic stress (ortholog); ASSOCIATED WITH malaria (ortholog); Skin Neoplasms (ortholog); FOUND IN ankyrin-1 complex (ortholog); external side of plasma m embrane (ortholog); plasma membrane (ortholog) | | | | Squirrel | 16 | description | gene, protein-coding, MODEL [RefSeq] |
| 12591288 | Lrrc8c | leucine rich repeat containing 8 VRAC subunit C | ENCODES a protein that exhibits volume-sensitive anion channel activity (inferred); INVOLVED IN aspartate transmembrane transport (ortholog); cellular response to osmotic stress (ortholog); fat cell differentiation (ortholog); ASSOCIATED WITH multiple sclerosis (ortholog); TIMES Syndrome (ortholog); FOUND IN cytoplasm (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred) | NW_004936537 | 9050495 | 9124649 | Squirrel | 23 | description | gene, protein-coding, MODEL [RefSeq] |
| 12686540 | Lrrc8e | leucine rich repeat containing 8 VRAC subunit E | ENCODES a protein that exhibits volume-sensitive anion channel activity (ortholog); INVOLVED IN aspartate transmembrane transport (inferred); cell volume homeostasis (inferred); cellular response to osmotic stress (inferred); ASSOCIATED WITH long QT syndrome (or tholog); FOUND IN cytoplasm (inferred); endoplasmic reticulum membrane (inferred); lysosomal membrane (inferred) | NW_004936588 | 4873412 | 4880574 | Squirrel | 23 | description | gene, protein-coding, MODEL [RefSeq] |
| 12725579 | Map2k7 | mitogen-activated protein kinase kinase 7 | ENCODES a protein that exhibits ATP binding (ortholog); JUN kinase kinase activity (ortholog); MAP kinase kinase activity (ortholog); INVOLVED IN cellular response to osmotic stress (ortholog); cellular response to sorbitol (ortholog); JNK cascade (ortholog); PA RTICIPATES IN adenosine signaling pathway; c-Jun N-terminal kinases MAPK signaling pathway; FasL mediated signaling pathway; ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); colon adenocarcinoma (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | NW_004936588 | 4882191 | 4891807 | Squirrel | 109 | description | gene, protein-coding, MODEL [RefSeq] |
| 12538215 | Ptger2 | prostaglandin E receptor 2 | ENCODES a protein that exhibits prostaglandin E receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress (ortholog); negative regulat ion of mucus secretion (ortholog); ASSOCIATED WITH allergic asthma (ortholog); asthma (ortholog); asthma, nasal polyps, and aspirin intolerance (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936697 | 2440943 | 2453897 | Squirrel | 46 | description | gene, protein-coding, MODEL [RefSeq] |
| 12728533 | Relb | RELB proto-oncogene, NF-kB subunit | ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN antigen processing and presentation (ortholog); cellular response to osmotic stress (ortholog); myeloid dendritic cell differentiation (ortholog); PARTICIPATES IN interleukin-12 signaling pathwa y; nuclear factor kappa B signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); atopic dermatitis (ortholog); breast cancer (ortholog); FOUND IN centrosome (inferred); chromatin (inferred); cytoplasm (inferred) | NW_004936706 | 1569603 | 1596831 | Squirrel | 79 | description | gene, protein-coding, MODEL [RefSeq] |
| 12561715 | Trpa1 | transient receptor potential cation channel subfamily A member 1 | ENCODES a protein that exhibits osmolarity-sensing monoatomic cation channel activity (ortholog); voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol (ortholog); calcium ion transport (ortholog); cellular response to caffeine (ortholog); ASSOCIATED WITH Abdominal Pain (ortholog); asthma (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog) | NW_004936648 | 1094460 | 1141394 | Squirrel | 85 | description | gene, protein-coding, MODEL [RefSeq] |
| 12722541 | Tsc22d4 | TSC22 domain family member 4 | INVOLVED IN response to osmotic stress (ortholog); FOUND IN cytoplasm (inferred); dendrite (inferred); nucleus (inferred) | NW_004936543 | 539222 | 549542 | Squirrel | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 12611031 | Usp15 | ubiquitin specific peptidase 15 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); INVOLVED IN regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASS OCIATED WITH chronic myeloid leukemia (ortholog); diabetic neuropathy (ortholog); FOUND IN cytoplasm (ortholog) | NW_004936545 | 978318 | 1094729 | Squirrel | 46 | description | gene, protein-coding, MODEL [RefSeq] |
| 12470363 | Wnk3 | WNK lysine deficient protein kinase 3 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); molecular condensate scaffold activity (inferred); INVOLVED IN cell volume homeostasis (ortholog); maintenance of blood-brain barrier (ortholog); osmosensory signaling pathway (o rtholog); ASSOCIATED WITH autistic disorder (ortholog); Neurodevelopmental Disorders (ortholog); Prieto syndrome (ortholog); FOUND IN adherens junction (inferred); bicellular tight junction (inferred); cytoplasm (inferred) | NW_004936751 | 1095578 | 1266772 | Squirrel | 48 | description | gene, protein-coding, MODEL [RefSeq] |
| 12515883 | Zfand1 | zinc finger AN1-type containing 1 | ENCODES a protein that exhibits metal ion binding (inferred); proteasome binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to heat (ortholog); cellular response to osmotic stress (ortholog); cellular response to oxidative stress (ort holog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred) | NW_004936656 | 2571757 | 2588385 | Squirrel | 19 | description | gene, protein-coding, MODEL [RefSeq] |