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Gene: Tsc22d4 (TSC22 domain family member 4) Ictidomys tridecemlineatus

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Symbol:

Tsc22d4

Name:

TSC22 domain family member 4

RGD ID:

12722541

Description:

INVOLVED IN glucose homeostasis (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); neuron cellular homeostasis (ortholog); ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN dendrite (ortholog); synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

TSC22 domain family protein 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	133,486,985 - 133,497,302 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936543	537,969 - 548,617 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936543	539,222 - 549,542 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

pleomorphic xanthoastrocytoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glucose homeostasis (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

neuron cellular homeostasis (ISO)

neuron projection extension (ISO)

regulation of transcription by RNA polymerase II (IEA)

response to osmotic stress (IEA,ISO)

Cellular Component

cytoplasm (IEA)

dendrite (ISO)

nucleus (IEA)

synapse (ISO)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tsc22d4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	133,486,985 - 133,497,302 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936543	537,969 - 548,617 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936543	539,222 - 549,542 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TSC22D4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	100,466,519 - 100,479,214 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	100,463,359 - 100,479,232 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	100,064,142 - 100,076,837 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	99,902,078 - 99,914,838 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	94,793,941 - 94,806,701 (-)	NCBI		Celera
Cytogenetic Map	7	q22.1	NCBI
HuRef	7	94,697,543 - 94,710,215 (-)	NCBI		HuRef
CHM1_1	7	99,994,757 - 100,007,518 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	101,706,601 - 101,719,289 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	99,424,226 - 99,436,987 (-)	NCBI

Tsc22d4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	137,744,274 - 137,758,011 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	137,743,992 - 137,766,712 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	137,745,969 - 137,768,453 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	137,745,730 - 137,768,450 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	138,187,224 - 138,200,975 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	137,975,784 - 137,989,539 (+)	NCBI		MGSCv36	mm8
Celera	5	134,732,531 - 134,746,249 (+)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	76.64	NCBI

Tsc22d4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	24,575,948 - 24,588,806 (-)	NCBI		GRCr8
mRatBN7.2	12	18,939,150 - 18,952,008 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	18,914,398 - 18,952,008 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	20,094,279 - 20,107,085 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	20,707,155 - 20,719,962 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	19,771,483 - 19,784,290 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	22,008,956 - 22,021,814 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	22,009,011 - 22,021,851 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	12	21,722,075 - 21,761,487 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	24,017,638 - 24,039,147 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	19,814,586 - 19,826,254 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	20,744,972 - 20,757,750 (-)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

Tsc22d4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955573	415,826 - 429,105 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955573	414,984 - 425,480 (+)	NCBI	ChiLan1.0	ChiLan1.0

TSC22D4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	118,379,740 - 118,392,879 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	166,644,372 - 166,657,180 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	92,495,407 - 92,508,204 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	105,887,295 - 105,909,981 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	105,896,307 - 105,909,967 (-)	Ensembl	panpan1.1		panPan2

TSC22D4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	9,196,199 - 9,206,929 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	9,197,197 - 9,211,885 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	10,900,933 - 10,911,479 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	9,130,449 - 9,140,993 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	9,126,041 - 9,145,943 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	8,982,924 - 8,993,466 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	8,960,443 - 8,971,023 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	9,142,821 - 9,153,385 (+)	NCBI		UU_Cfam_GSD_1.0

LOC100514038
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	8,395,229 - 8,406,218 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	8,390,945 - 8,406,240 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	7,734,046 - 7,750,006 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TSC22D4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	12,729,798 - 12,744,222 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	28	12,730,714 - 12,745,483 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666070	3,552,822 - 3,565,856 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tsc22d4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	16,589,309 - 16,600,155 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624740	16,582,726 - 16,598,477 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005328451	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000032031 ⟹ ENSSTOP00000025981

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936543	537,969 - 548,617 (-)	Ensembl

Ensembl Acc Id:

ENSSTOT00000034607 ⟹ ENSSTOP00000031237

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936543	539,700 - 540,630 (-)	Ensembl

Ensembl Acc Id:

ENSSTOT00000042494 ⟹ ENSSTOP00000027356

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936543	539,700 - 540,792 (-)	Ensembl

RefSeq Acc Id:

XM_005328451 ⟹ XP_005328508

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	133,486,985 - 133,497,302 (+)	NCBI
SpeTri2.0	NW_004936543	539,222 - 549,542 (-)	NCBI

Sequence:

show sequence

AGGAGAGGAGCTGTGAGCAGGCCCGAGGAGGCAGGACTTCCTGGTGTGGGGGTTGTCAACAGCC
CAGAAAGAGAAAGACAGAGACAGAGACCGAGAAGAGCTGAGGAACCAAGAGACGGATCCAGCAG
GGCCACGCGGGAAAAGCCTTGGGAGACCCACTTGTCCGGGACCGCCGAGACCCGCTGCCACCTG
GAGCAGCTGGGGGCTGAGCCGCCCCCTCCCACAGCCGTCGGGAGACCCGTGGGGCTGCAGAGGC
CGCGCCTGGACTCCTCCTCCGAGGCGCGGGTTCCTTCTTTTCTGGACAGCAAACTTTCCACGGA
GATGCCTCGCAGGATGAGGTGCGGCCTCCGAAGAACTCCGGGCAGCTCCTGATCGCTGCCTGCG
TCCCCCGCATTGACCGGGGACAGGCGGCCCCAGGAGAAGGACAGCCCGACATCTTAGTCGCTGA
GACCCCTGGCTCAGCTCGGTGACTGAGACCCGAGAGTTTGCAAACTCAGCTCTGGAGTTCAGCA
GCGACAGCAGCAGGAAAAACCTGCCCCTGCCCCTGCCCCCCCCTCCCGCCACCTCTCCTCCCCT
GTTCTCCCGTCCCCAACCAGGCACCCCCAGTTCTTTCAAGGCCCTCTTACCATGTCGGACCCAG
ACGTCACTAGGGGCCCTGATGCCCCCGCCATGTGGCCCCCCTGTTCCAGGGGTGCCTGAGCCCC
TTCTAGGAGCCCAGCCCCTCCCCCACCCCTACTCGTTCTGAGCCCCAGGGACCATGAGTGGGGG
CAAGAAGAAGAGCAGTTTCCAAATCACCAGCGTCACCACGGACTACGAGGGCCCAGGGAGCCCA
GGGGCTTCAGATTCCCCTGCTTCGACGGCCCCCACCGGGCCCCCACCACGCCTTCCCAACGGGG
AGCCCAACCCTGATCCAGGGGGCAGGAGCACCCCCCGGAATGGCTCCCCACCACCTGGGGCCCC
TGCCTCCCGTTTCCGGGTGGTGAAGCTGCCCCACGGCCTGGGAGAGCCTTATCGCCGAGGTCGT
TGGACGTGTGTGGATGTTTACGAGAGAGACCTGGAGCCCCCGAGCTTCAGCCGCCTCTTGGAGG
GAATTCGAGGGGCCTCGGGGGGCACTGGGGGCAGATCTTTGGATTCCAGGTTGGAGCTGGCCAG
CTTGGGCCTGGGTGCCCCCATGCCACAGTCAGGCCTGTCTCAGGGCCCCACCTCCTGGCTCCGC
CCACCCCCCACCTCCCCTGGACCTCAAGCCCGCTCCTTCACTGGGGGACTGGGCCAGCTGGCGG
TTCCTGGCAAGGCCAAGGCGGAGACACCCCTCCTATCAGCCTCCCCACCCCAGCAGCGCCCCCC
AGAGCCTGGGACTGGGGATAGCACGGGCACATCCCTGGCTGCCACACCCCTGCCCTCCCTGAGG
GTGGAGGTAGAGGCTGGGGGGTCCGCAGCTGGGACCCCTCCACTGTCCCGGAGGAGAGATGGAG
CCCAACGGCTGAGGATGGAGTTGGTTCCTCCAGAGGAGACAGGGCAGGTGCCCCCATTTGACTC
CCGCCCCAGCTCCCCGGCCCTCTACTTTGATGCCAGTCTGGTTCACAAGTCTCCAGACCCCTTT
GGAGCAGCAGCAGCCCAGAGCCTCAGCCTGGCCCGTTCCATGTTGGCCATCAGTGGTCACTTGG
ACAGCGATGACGATAGCGGCTCCGGAAGCCTGGTTGGCATTGACAACAAGATCGAACAAGCCAT
GGACTTGGTAAAGTCCCACCTCATGTTTGCGGTCCGGGAGGAGGTGGAGGTGCTGAAGGAGCAG
ATCCGAGACCTGGCAGAGCGGAACGCCGCGCTGGAGCAGGAGAACGGACTGCTGCGTGCCCTGG
CCAGCCCAGAGCAGCTGGCACAGCTGCCCTCCTCGGGGCTCCCACGGCTTGGGCCCCCTGCGCC
CAACGGGCCCTCCGTCTGAGCCTCCCTTCCCTCACAATGTGCCTTTGGGGGCTGCCATGGTCGC
CAGGCTTTGCGCCAGCAGCCTGCCCCCTCTTCCTATGCAGCTTTAATGCCCCCTGACCCCCAGG
GATGGGATTTTCAGGCTCAGTACTGTCAGTACTGGCCTGTTCCCCGCCTTGCCCCCGTCCCCGC
CTTGGTCCTCAGGTCTCGATGGAGGGGGGAGGGCTCGGAATGGGGTGCTAGATGGAGCCCCCTC
CATGAGAGATCCCAGCCCCCTCCCTCCCTGGGTGTCAGTGTTCTGGGTTCCCCAGCAGTAGATG
GCTTGGGGGAGTCGGAGGCTCCCTGGCAACAATCCCCCCCACACTTTGTTCCCCTCAAAGTGCT
CCCTCTCCACTGCCCAGGGGAGGGCATATGGACAGTGTCTGGAAGTTCTGGGTTTCAGGTTGTT
ATTAAAATAATAATTATAATTAAAAAATCTGAAGAAACTTGAATTTGGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005328508	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000025981.1
	ENSSTOP00000027356.1
	ENSSTOP00000031237.1
GenBank Protein	KAG3259910	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005328508 ⟸ XM_005328451

- UniProtKB:

A0A287CXH2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSGGKKKSSFQITSVTTDYEGPGSPGASDSPASTAPTGPPPRLPNGEPNPDPGGRSTPRNGSPP
PGAPASRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPPSFSRLLEGIRGASGGTGGRSLDSRL
ELASLGLGAPMPQSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLAVPGKAKAETPLLSASPPQ
QRPPEPGTGDSTGTSLAATPLPSLRVEVEAGGSAAGTPPLSRRRDGAQRLRMELVPPEETGQVP
PFDSRPSSPALYFDASLVHKSPDPFGAAAAQSLSLARSMLAISGHLDSDDDSGSGSLVGIDNKI
EQAMDLVKSHLMFAVREEVEVLKEQIRDLAERNAALEQENGLLRALASPEQLAQLPSSGLPRLG
PPAPNGPSV

hide sequence

Ensembl Acc Id:

ENSSTOP00000025981 ⟸ ENSSTOT00000032031

Ensembl Acc Id:

ENSSTOP00000031237 ⟸ ENSSTOT00000034607

Ensembl Acc Id:

ENSSTOP00000027356 ⟸ ENSSTOT00000042494

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000030762	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000032031.1	UniProtKB/TrEMBL
	ENSSTOT00000034607.1	UniProtKB/TrEMBL
	ENSSTOT00000042494.1	UniProtKB/TrEMBL
Gene3D-CATH	Single helix bin	UniProtKB/TrEMBL
InterPro	TSC-22_Dip_Bun	UniProtKB/TrEMBL
	TSC22/BUN_CS	UniProtKB/TrEMBL
	TSC22D4	UniProtKB/TrEMBL
NCBI Gene	Tsc22d4	ENTREZGENE
PANTHER	PTHR47610	UniProtKB/TrEMBL
	TSC22 DOMAIN FAMILY PROTEIN 4	UniProtKB/TrEMBL
Pfam	TSC22	UniProtKB/TrEMBL
PROSITE	TSC22	UniProtKB/TrEMBL
Superfamily-SCOP	Delta-sleep-inducing peptide immunoreactive peptide	UniProtKB/TrEMBL
UniProt	A0A287CXH2	ENTREZGENE, UniProtKB/TrEMBL
	A0A287D189_ICTTR	UniProtKB/TrEMBL
	A0A287DCE6_ICTTR	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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