TSC22D4 (TSC22 domain family member 4) - Rat Genome Database

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Gene: TSC22D4 (TSC22 domain family member 4) Chlorocebus sabaeus
Analyze
Symbol: TSC22D4
Name: TSC22 domain family member 4
RGD ID: 18695368
Description: INVOLVED IN response to osmotic stress (ortholog); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TSC22 domain family protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,729,798 - 12,744,222 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,730,714 - 12,745,483 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,552,822 - 3,565,856 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TSC22D4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,729,798 - 12,744,222 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,730,714 - 12,745,483 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,552,822 - 3,565,856 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TSC22D4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,466,519 - 100,479,214 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,463,359 - 100,479,232 (-)EnsemblGRCh38hg38GRCh38
GRCh377100,064,142 - 100,076,837 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,902,078 - 99,914,838 (-)NCBINCBI36Build 36hg18NCBI36
Celera794,793,941 - 94,806,701 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,697,543 - 94,710,215 (-)NCBIHuRef
CHM1_1799,994,757 - 100,007,518 (-)NCBICHM1_1
T2T-CHM13v2.07101,706,601 - 101,719,289 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,424,226 - 99,436,987 (-)NCBI
Tsc22d4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,744,274 - 137,758,011 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,743,992 - 137,766,712 (+)EnsemblGRCm39 Ensembl
GRCm385137,745,969 - 137,768,453 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,745,730 - 137,768,450 (+)EnsemblGRCm38mm10GRCm38
MGSCv375138,187,224 - 138,200,975 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365137,975,784 - 137,989,539 (+)NCBIMGSCv36mm8
Celera5134,732,531 - 134,746,249 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.64NCBI
Tsc22d4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81224,575,948 - 24,588,806 (-)NCBIGRCr8
mRatBN7.21218,939,150 - 18,952,008 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1218,914,398 - 18,952,008 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1220,094,279 - 20,107,085 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01220,707,155 - 20,719,962 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01219,771,483 - 19,784,290 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,008,956 - 22,021,814 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,009,011 - 22,021,851 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,722,075 - 21,761,487 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,017,638 - 24,039,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41219,814,586 - 19,826,254 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1220,744,972 - 20,757,750 (-)NCBICelera
Cytogenetic Map12q12NCBI
Tsc22d4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573415,826 - 429,105 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955573414,984 - 425,480 (+)NCBIChiLan1.0ChiLan1.0
TSC22D4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,379,740 - 118,392,879 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,644,372 - 166,657,180 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,495,407 - 92,508,204 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,887,295 - 105,909,981 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,896,307 - 105,909,967 (-)Ensemblpanpan1.1panPan2
TSC22D4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,196,199 - 9,206,929 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,197,197 - 9,211,885 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,900,933 - 10,911,479 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.069,130,449 - 9,140,993 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,126,041 - 9,145,943 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.168,982,924 - 8,993,466 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.068,960,443 - 8,971,023 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,142,821 - 9,153,385 (+)NCBIUU_Cfam_GSD_1.0
Tsc22d4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,486,985 - 133,497,302 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543537,969 - 548,617 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543539,222 - 549,542 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100514038
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,395,229 - 8,406,218 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,390,945 - 8,406,240 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,734,046 - 7,750,006 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Tsc22d4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,589,309 - 16,600,155 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,582,726 - 16,598,477 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 14 58
Low 6 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000015997   ⟹   ENSCSAP00000013922
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2812,730,714 - 12,745,483 (+)Ensembl
RefSeq Acc Id: XM_008018549   ⟹   XP_008016740
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12812,729,798 - 12,744,222 (+)NCBI
Vero_WHO_p1.0NW_0236660703,552,822 - 3,565,842 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037990419   ⟹   XP_037846347
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660703,552,822 - 3,565,856 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008016740 (Get FASTA)   NCBI Sequence Viewer  
  XP_037846347 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013922
  ENSCSAP00000013922.1
Reference Protein Sequences
RefSeq Acc Id: XP_008016740   ⟸   XM_008018549
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RZ83 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013922   ⟸   ENSCSAT00000015997
RefSeq Acc Id: XP_037846347   ⟸   XM_037990419
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017902 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015997.1 UniProtKB/TrEMBL
Gene3D-CATH Single helix bin UniProtKB/TrEMBL
InterPro TSC-22_Dip_Bun UniProtKB/TrEMBL
  TSC22/BUN_CS UniProtKB/TrEMBL
  TSC22D4 UniProtKB/TrEMBL
KEGG Report csab:103246737 UniProtKB/TrEMBL
NCBI Gene TSC22D4 ENTREZGENE
PANTHER PTHR47610 UniProtKB/TrEMBL
  TSC22 DOMAIN FAMILY PROTEIN 4 UniProtKB/TrEMBL
Pfam TSC22 UniProtKB/TrEMBL
PROSITE TSC22 UniProtKB/TrEMBL
Superfamily-SCOP Delta-sleep-inducing peptide immunoreactive peptide UniProtKB/TrEMBL
UniProt A0A0D9RZ83 ENTREZGENE, UniProtKB/TrEMBL