| 12119451 | TP53 | tumor protein p53 | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); ATP-dependent DNA/DNA annealing activity (ortholog); copper ion binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II; apoptotic signaling pathway (ortholog); cellular response to glucose starvatio n (ortholog); PARTICIPATES IN altered p53 signaling pathway; endometrial cancer pathway; lung non-small cell carcinoma pathway; ASSOCIATED WITH Acute Erythroleukemia (ortholog); acute kidney failure (ortholog); acute lymphoblastic leukemia (ortholog); FOUND IN centrosome (ortholog); chromatin (ortholog); cytoplasm (ortholog); INTERACTS WITH toosendanin | 5 | 32561406 | 32565149 | Dog | 1166 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12295025 | TP53TG5 | TP53 target 5 | FOUND IN chromosome (inferred); nucleolus (inferred) | 24 | 32672193 | 32675873 | Dog | 2 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12193967 | TP53RK | TP53 regulating kinase | ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); hydrolase activity (inferred); INVOLVED IN protein phosphorylation (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); Galloway-Mowat syndrome (ortholog); Galloway-Mowat syndrome 4 (ortholog); FOUND IN cytoplasm (inferred); EKC/KEOPS complex (inferred); nucleus (inferred) | 24 | 33895530 | 33898461 | Dog | 37 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12380128 | LOC100688975 | TP53 regulating kinase pseudogene | | 22 | 57870744 | 57871184 | Dog | | name | gene, pseudo, MODEL [RefSeq] |
| 12124119 | WRAP53 | WD repeat containing antisense to TP53 | ENCODES a protein that exhibits histone binding (inferred); identical protein binding (inferred); protein carrier chaperone (inferred); INVOLVED IN positive regulation of telomere maintenance via telomerase (ortholog); ASSOCIATED WITH Autosomal Recessive Dyskeratosis Congenita (ortholog); autosomal recessive dyskeratosis congenita 3 (ortholog); Body Weight (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density membrane (ortholog) | 5 | 32574153 | 32586222 | Dog | 67 | name | gene, protein-coding, MODEL [RefSeq] |
| 12304710 | TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | ENCODES a protein that exhibits p53 binding (ortholog); INVOLVED IN cellular response to UV (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); mitotic G1 DNA damage checkpoint signaling (ortholog); FOUND IN mitochondrial intermembrane space (ortholog); mitochondri on (ortholog); protein-containing complex (ortholog) | 26 | 16349513 | 16352805 | Dog | 24 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13324663 | LOC111094306 | TP53-regulated inhibitor of apoptosis 1-like | | 36 | 4234997 | 4236093 | Dog | | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 40917070 | LOC119874533 | TP53-regulated inhibitor of apoptosis 1-like | | | | | Dog | | name | gene, pseudo, MODEL [RefSeq] |
| 12168136 | TIGAR | TP53 induced glycolysis regulatory phosphatase | ENCODES a protein that exhibits catalytic activity (inferred); fructose-2,6-bisphosphate 2-phosphatase activity (inferred); hydrolase activity (inferred); INVOLVED IN fructose 2,6-bisphosphate metabolic process (ortholog); intestinal epithelial cell development (ortholog); negative regulation of glu cose catabolic process to lactate via pyruvate (ortholog); ASSOCIATED WITH Nerve Degeneration (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrial outer membrane (inferred) | 27 | 40521751 | 40549304 | Dog | 46 | name | gene, protein-coding, MODEL [RefSeq] |
| 40909273 | RPRM | reprimo, TP53 dependent G2 arrest mediator homolog | INVOLVED IN regulation of cell cycle (ortholog); regulation of mitotic cell cycle (ortholog); ASSOCIATED WITH Barrett's esophagus (ortholog); Esophageal Neoplasms (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred) | | | | Dog | 11 | name | gene, protein-coding, MODEL [RefSeq] |
| 12162289 | RRM2B | ribonucleotide reductase regulatory TP53 inducible subunit M2B | ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN deoxyribonucleoside triphosphate metabolic process (ortholog); deoxyribonucleotide biosynthetic process (ortholog); DNA repair (ortholog); PARTICIPATES IN beta-ureidopropionase deficiency pathway; dihydropyrimidinase deficiency pathway; gemcitabine pharmacodynamics pathway; ASSOCIATED WITH autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 5 (ortholog); Camptocormia (ortholog); chronic progressive external ophthalmoplegia (ortholog); FOUND IN cytosol (inferred); mitochondrion (inferred); nucleoplasm (inferred) | 13 | 3774725 | 3838576 | Dog | 63 | name | gene, protein-coding, MODEL [RefSeq] |
| 12324739 | TP53BP1 | tumor protein p53 binding protein 1 | ENCODES a protein that exhibits DNA binding (inferred); histone H4K20me methyltransferase activity (inferred); histone H4K20me2 reader activity (inferred); INVOLVED IN cellular response to X-ray (ortholog); DNA damage response (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); glioblastoma (ortholog); FOUND IN site of double-strand break (ortholog) | 30 | 10263650 | 10362646 | Dog | 83 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12060131 | PERP | p53 apoptosis effector related to PMP22 | INVOLVED IN amelogenesis (ortholog); desmosome organization (ortholog); heterotypic cell-cell adhesion (ortholog); ASSOCIATED WITH Erythrokeratodermia Variabilis et Progressiva 7 (ortholog); genetic disease (ortholog); Olmsted Syndrome 2 (ortholog); FOUND IN cytoplasm (inferred); desmosome (inferred ); Golgi apparatus (inferred) | 1 | 30418847 | 30435287 | Dog | 31 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 40922173 | TP53I3 | tumor protein p53 inducible protein 3 | ENCODES a protein that exhibits oxidoreductase activity (inferred); INVOLVED IN apoptotic process (ortholog); reactive oxygen species biosynthetic process (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); autism spectrum disorder (ortholog); carcinoma (ortholog) | 17 | 18560123 | 18566588 | Dog | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12097757 | TP53BP2 | tumor protein p53 binding protein 2 | ENCODES a protein that exhibits identical protein binding (inferred); NF-kappaB binding (inferred); p53 binding (inferred); INVOLVED IN positive regulation of cellular process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH breast lobular carcinoma (ortholog); Breast Neoplasms (or tholog); chromosome 1q41-q42 deletion syndrome (ortholog); FOUND IN cell junction (inferred); cytoplasm (inferred); cytosol (inferred) | 7 | 40296278 | 40329818 | Dog | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12239554 | TP53I11 | tumor protein p53 inducible protein 11 | FOUND IN membrane (inferred) | 18 | 44372619 | 44386675 | Dog | 1 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12201675 | TP53I13 | tumor protein p53 inducible protein 13 | INVOLVED IN negative regulation of cell cycle (inferred); response to UV (inferred); response to xenobiotic stimulus (inferred); FOUND IN cytoplasm (inferred) | 9 | 43671184 | 43676330 | Dog | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12235144 | TP53INP1 | tumor protein p53 inducible nuclear protein 1 | ENCODES a protein that exhibits antioxidant activity (inferred); INVOLVED IN cellular response to ethanol (ortholog); cellular response to hydroperoxide (ortholog); cellular response to methyl methanesulfonate (ortholog); ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); FOUND IN au tophagosome (inferred); cytoplasmic vesicle (inferred); cytosol (inferred) | 29 | 39575782 | 39593389 | Dog | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12199624 | TP53INP2 | tumor protein p53 inducible nuclear protein 2 | INVOLVED IN autophagosome assembly (inferred); autophagy (inferred); DNA-templated transcription (inferred); FOUND IN autophagosome (inferred); cytoplasmic vesicle (inferred); cytosol (inferred) | 24 | 23768208 | 23801268 | Dog | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12427821 | TPRKB | TP53RK binding protein | ENCODES a protein that exhibits protein kinase binding (inferred); INVOLVED IN tRNA processing (inferred); tRNA threonylcarbamoyladenosine modification (inferred); ASSOCIATED WITH Galloway-Mowat syndrome (ortholog); Galloway-Mowat syndrome 5 (ortholog); nephrotic syndrome (ortholog); FOUND IN cytopl asm (inferred); cytosol (inferred); EKC/KEOPS complex (inferred) | 17 | 49271845 | 49278794 | Dog | 19 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |