| 12079506 | INO80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits actin binding (inferred); alpha-tubulin binding (inferred); ATP binding (inferred); INVOLVED IN cell division (inferred); cellular response to ionizing radiation (inferred); cellular response to UV (inferred); PARTICIPATES IN INO80 > family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN chromosome (inferred); cytosol (inferred); Ino80 complex (inferred) | 30 | 8100536 | 8229868 | Dog | 75 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12339646 | INO80B | INO80 complex subunit B | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 yle='font-weight:700;'>Ino80 complex (inferred); nuclear body (inferred); nucleolus (inferred) | 17 | 48674004 | 48676869 | Dog | 23 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12402575 | INO80C | INO80 complex subunit C | INVOLVED IN chromatin remodeling (inferred); DNA-templated transcription (inferred); positive regulation of DNA repair (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (inferred); Ino80 700;'>Ino80 complex (inferred); MLL1 complex (inferred); INTERACTS WITH bisphenol A | 7 | 54569954 | 54586902 | Dog | 25 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12148691 | INO80D | INO80 complex subunit D | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (inferred) | 37 | 14581531 | 14647930 | Dog | 14 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12234447 | INO80E | INO80 complex subunit E | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA-templated transcription (inferred); regulation of cell cycle (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (orth olog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | 6 | 18033366 | 18041604 | Dog | 21 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12113188 | ACTL6A | actin like 6A | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN blastocyst formation (ortholog); chromatin remodeling (ortholog); spinal cord development (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 fa mily mediated chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); cervical dystonia (ortholog); Developmental Disabilities (ortholog); FOUND IN Ino80 complex (inferred); npBAF complex (inferred); NuA4 histone acetyltransferase complex (inferred) | 34 | 12922506 | 12988334 | Dog | 66 | description | gene, protein-coding, MODEL [RefSeq] |
| 12091099 | ACTR5 | actin related protein 5 | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplas m (inferred); Ino80 complex (inferred); nucleus (inferred) | 24 | 27154283 | 27190947 | Dog | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 12150482 | ACTR8 | actin related protein 8 | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN cell division (inferred); chromatin remodeling (inferred); DNA damage response (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUN D IN chromosome (inferred); Ino80 complex (inferred); nucleoplasm (inferred) | 20 | 36118471 | 36135064 | Dog | 33 | description | gene, protein-coding, MODEL [RefSeq] |
| 12419875 | NFRKB | nuclear factor related to kappaB binding protein | ENCODES a protein that exhibits DNA binding (inferred); protease binding (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 f amily mediated chromatin remodeling pathway; FOUND IN Ino80 complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 5 | 4944278 | 4982377 | Dog | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 12261807 | ACTB | actin beta | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); identical protein binding (ortholog); kinesin binding (ortholog); INVOLVED IN adherens junction assembly (ortholog); apical protein localization (ortholog); axonogenesis (ortholog); PARTICIPATES IN auditory mechanotransduction pathw ay; INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); Animal Mammary Neoplasms (ortholog); Baraitser-Winter syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); adherens junction (ortholog); apical junction complex (ortholog) | 6 | 12421006 | 12424449 | Dog | 180 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 12203187 | ACTR6 | actin related protein 6 | INVOLVED IN nucleolus organization (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (inferred); cytoskeleton (inferred); nucleolus (inferred) | 15 | 39312863 | 39342208 | Dog | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 12064692 | BRD8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (inferred); transcription coactivator activity (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma (ortholog); endometriosis (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 11 | 25793375 | 25825868 | Dog | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 12351897 | DMAP1 | DNA methyltransferase 1 associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (inferred); transcription corepressor activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); response to ethanol (ortholog); PARTICIPATES IN INO80 ='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); cytosol (inferred) | 15 | 16077164 | 16085666 | Dog | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 12432924 | EP400 | E1A binding protein p400 | ENCODES a protein that exhibits chromatin binding (ortholog); protein antigen binding (ortholog); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nuclear speck (inferred); nucleoplasm (inferred) | 26 | 848028 | 951135 | Dog | 45 | description | gene, protein-coding, MODEL [RefSeq] |
| 12264107 | EPC1 | enhancer of polycomb homolog 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (ortholog); enzyme-substrate adaptor activity (ortholog); INVOLVED IN double-strand break repair via homologous recombination (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of gene expr ession, epigenetic (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN nuclear body (ortholog); nuclear membrane (ortholog); nucleolus (ortholog) | 2 | 14566177 | 14659774 | Dog | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 12262168 | EPC2 | enhancer of polycomb homolog 2 | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleus (inferred) | 19 | 50356490 | 50484405 | Dog | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 12358492 | ING3 | inhibitor of growth family member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (inferred); histone H3K4me3 reader activity (inferred); histone H4 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (inferred); PAR TICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 14 | 59067282 | 59093399 | Dog | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 12397322 | KAT5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); phospholipase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to X-ray (ortholog); lipid droplet disassembly (ortholog); PARTICIPATES IN a taxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); protein-containing complex (ortholog) | 18 | 51499615 | 51507434 | Dog | 112 | description | gene, protein-coding, MODEL [RefSeq] |
| 12083817 | MCRS1 | microspherule protein 1 | ENCODES a protein that exhibits telomerase inhibitor activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomere lengthening (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN dendrite (ortholog ); perikaryon (ortholog) | 27 | 5076075 | 5085483 | Dog | 61 | description | gene, protein-coding, MODEL [RefSeq] |
| 12255673 | MEAF6 | MYST/Esa1 associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (inferred); histone H4K12 acetyltransferase activity (inferred); histone H4K5 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (i nferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN histone acetyltransferase complex (inferred); kinetochore (inferred); MOZ/MORF histone acetyltransferase complex (inferred) | 15 | 4944059 | 4971573 | Dog | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 12302353 | MORF4L1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN cell population proliferation (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN NuA4 histone ace tyltransferase complex (inferred); nuclear speck (inferred); nucleus (inferred) | 3 | 58127152 | 58149709 | Dog | 39 | description | gene, protein-coding, MODEL [RefSeq] |
| 12189404 | MORF4L2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of striated muscle cell differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleolus (inferred); nucleopla sm (inferred); nucleus (inferred) | X | 77084940 | 77097900 | Dog | 27 | description | gene, protein-coding, MODEL [RefSeq] |
| 12157113 | MRGBP | MRG domain binding protein | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH neuronal ceroid lipofuscinosis (ortholog); FOUND IN H4/H2A histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 24 | 46634580 | 46637222 | Dog | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 12434129 | RUVBL1 | RuvB like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of plasminogen activation (ortholog); regulation of fibroblast apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear matrix (ortholog); protein-containing complex (ortholog) | 20 | 2095807 | 2137528 | Dog | 73 | description | gene, protein-coding, MODEL [RefSeq] |
| 12175919 | RUVBL2 | RuvB like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN gene expression (ortholog); telomerase RNA localization to Cajal body (ortholog); PARTICIPATES IN INO80 family mediated chromatin remo deling pathway; FOUND IN cytoplasm (inferred); cytosol (inferred); dynein axonemal particle (inferred) | 1 | 107384328 | 107400849 | Dog | 82 | description | gene, protein-coding, MODEL [RefSeq] |
| 12386809 | SRCAP | Snf2 related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (inferred); chromatin organization (inferred); chromatin remodeling (inferred); PARTICIPATES IN INO80 family mediated chromatin remode ling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleus (ortholog) | 6 | 17437097 | 17470724 | Dog | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 12312628 | TFPT | TCF3 fusion partner | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN actin filament (ortholog) | 1 | 103090723 | 103098601 | Dog | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 12108323 | TRRAP | transformation/transcription domain associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regu lation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (ortholog); Swr1 complex (ortholog); transcription factor TFTC complex (ortholog) | 6 | 10519734 | 10635175 | Dog | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 12325188 | UCHL5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); endopeptidase inhibitor activity (inferred); INVOLVED IN regulation of AMPA receptor activity (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH alcohol-associated liver disease (ortholog); Experimental Diabetes Mellitus (ortholog); Testis Reperfusion Injury (ortholog); FOUND IN cytosolic proteasome complex (ortholog); synaptic vesicle (ortholog) | 38 | 6004595 | 6045999 | Dog | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 12429933 | VPS72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (inferred); histone chaperone activity (inferred); INVOLVED IN somatic stem cell population maintenance (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (inferr ed); protein-containing complex (inferred) | 17 | 60239299 | 60252323 | Dog | 16 | description | gene, protein-coding, MODEL [RefSeq] |
| 12334230 | YEATS4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (inferred); histone H3K27ac reader activity (inferred); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma (ortholog); liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 10 | 11364435 | 11382340 | Dog | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 12360152 | YY1 | YY1 transcription factor | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); camera-type eye morphogenesis (ortholog); cellular response to interleukin-1 (ortholog); PARTICIPATES IN INO80 family media ted chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy 78 (ortholog); FOUND IN nuclear matrix (ortholog); nucleus (ortholog); ribonucleoprotein complex (ortholog) | 8 | 68539511 | 68572796 | Dog | 134 | description | gene, protein-coding, MODEL [RefSeq] |
| 12238103 | ZNHIT1 | zinc finger HIT-type containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone deacetylase binding (inferred); INVOLVED IN negative regulation of G0 to G1 transition (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of T cell proliferatio n (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (inferred) | 6 | 8658288 | 8663511 | Dog | 37 | description | gene, protein-coding, MODEL [RefSeq] |