| 12050329 | ENAM | enamelin | INVOLVED IN ameloblast differentiation (ortholog); amelogenesis (ortholog); odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH amelogenesis imperfecta; amelogenesis imperfecta type 1B (ortholog); amelogenesis imperfecta type 1C (ortholog); FOUND IN extracellular matrix (ortholog) | 13 | 59934299 | 59948279 | Dog | 21 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12292767 | MMP20 | matrix metallopeptidase 20 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN amelogenesis (ortholog); extracellular matrix disassembly (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH amelogenesis imperfecta hypom aturation type 2A2 (ortholog); amelogenesis imperfecta type 1C (ortholog); autosomal dominant intellectual developmental disorder 56 (ortholog); FOUND IN extracellular matrix (inferred) | 5 | 29106717 | 29154628 | Dog | 25 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12233051 | ADGRF2 | adhesion G protein-coupled receptor F2 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); gene expression (ortholog); ASSOCIATED WITH autistic diso rder (ortholog); FOUND IN membrane (inferred) | 12 | 15716866 | 15739690 | Dog | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 12264726 | AMBN | ameloblastin | ENCODES a protein that exhibits structural constituent of tooth enamel (inferred); INVOLVED IN regulation of cell population proliferation (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 1F (ortholog); BCARD syndrome (ortholog); osteoporosis-pseudogliom a syndrome (ortholog) | 13 | 59899968 | 59912699 | Dog | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 12072321 | AMTN | amelotin | INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane (inferred); cell-cell junction (inferred); extracellular mat rix (inferred) | 13 | 59855278 | 59867133 | Dog | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 12318329 | CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | ENCODES a protein that exhibits magnesium ion transmembrane transporter activity (inferred); sodium ion transmembrane transporter activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN enamel mineralization (ortholog); magnesium ion home ostasis (ortholog); magnesium ion transport (ortholog); ASSOCIATED WITH Amaurosis Hypertrichosis (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN dendrite (ortholog); neuronal cell body (ortholog) | 10 | 45157418 | 45197323 | Dog | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 12420669 | CTBP1 | C-terminal binding protein 1 | ENCODES a protein that exhibits chromatin binding (ortholog); identical protein binding (ortholog); lncRNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); Notch signaling pathway (ortholog); presynapse to nucleus signaling pathway (ortholog); PAR TICIPATES IN Notch signaling pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); genetic disease (ortholog); HYPOTONIA, ATAXIA, DEVELOPMENTAL DELAY, AND TOOTH ENAMEL DEFECT SYNDROME (ortholog); FOUND IN cytoplasm (ortholog); extrinsic component of presynaptic endocytic zone membrane (ortholog); GABA-ergic synapse (ortholog) | 3 | 91385733 | 91400252 | Dog | 96 | description | gene, protein-coding, MODEL [RefSeq] |
| 12382461 | DMP1 | dentin matrix acidic phosphoprotein 1 | ENCODES a protein that exhibits calcium ion binding (ortholog); Hsp70 protein binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); regulation of enamel mineralization (ortholog); ASSOCIATED WITH autosomal recessive hypophosphatemic rickets (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); extracellular matrix (inferred); nucleus (inferred) | 32 | 11022900 | 11053900 | Dog | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 12427477 | FAM20A | FAM20A golgi associated secretory pathway pseudokinase | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN enamel mineralization (ortholog); positive regulation of protein phosphorylation (ortholog); response to bacterium (ortholog); ASSOCIATED WITH amelogenesis imperfect a type 1G (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (inferred); endoplasmic reticulum (inferred); extracellular space (inferred) | 9 | 15205887 | 15218873 | Dog | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 12432310 | FAM20C | FAM20C golgi associated secretory pathway kinase | ENCODES a protein that exhibits calcium ion binding (ortholog); manganese ion binding (ortholog); protease binding (ortholog); INVOLVED IN biomineral tissue development (ortholog); dentinogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amel ogenesis imperfecta; COVID-19 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); Golgi membrane (ortholog) | 6 | 16448603 | 16497064 | Dog | 48 | description | gene, protein-coding, MODEL [RefSeq] |
| 12212417 | FOSL2 | FOS like 2, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN alveolar secondary septum development (ortholog); B cell differentiation (ortholog); B cell proliferation (ortholog); ASSOCIATED WITH APLA SIA CUTIS-ENAMEL DYSPLASIA SYNDROME (ortholog); colon adenocarcinoma (ortholog); colorectal cancer (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); transcription factor AP-1 complex (inferred) | 17 | 22340469 | 22364994 | Dog | 141 | description | gene, protein-coding, MODEL [RefSeq] |
| 12117701 | KLK4 | kallikrein related peptidase 4 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); peptidase activity (inferred); INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); extracellular matrix disassembly (ortholog); ASSOCIATED WITH amelog enesis imperfecta (ortholog); amelogenesis imperfecta type 2A1 (ortholog); breast cancer (ortholog); FOUND IN extracellular region (inferred) | 1 | 105950948 | 105955464 | Dog | 27 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 12394910 | STIM1 | stromal interaction molecule 1 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); channel activator activity (ortholog); identical protein binding (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); detection of calcium ion (ortholog); enam '>enamel mineralization (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH colorectal cancer (ortholog); common variable immunodeficiency 10 (ortholog); congenital structural myopathy (ortholog); FOUND IN cortical endoplasmic reticulum (ortholog); growth cone (ortholog); plasma membrane (ortholog) | 21 | 26394592 | 26594764 | Dog | 109 | description | gene, protein-coding, MODEL [RefSeq] |
| 12168669 | WDR72 | WD repeat domain 72 | INVOLVED IN ameloblast differentiation (ortholog); amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta hypomaturation type 2A3 (ortholog); amelogenesis imperfecta type 1C (ortholo g); FOUND IN endosome (ortholog); extracellular region (ortholog); nucleus (ortholog) | 30 | 19120021 | 19340781 | Dog | 37 | description | gene, protein-coding, MODEL [RefSeq] |