Ras association (RalGDS/AF-6) domain family member 1
Enables small GTPase binding activity. Predicted to be involved in several processes, including Ras protein signal transduction; positive regulation of protein ubiquitination; and protein stabilization. Predicted to act upstream of with a negative effect on regulation of cell cycle G1/S phase transi
tion. Predicted to be located in cytoplasm and microtubule cytoskeleton. Predicted to be active in microtubule cytoskeleton and nucleus. Is expressed in liver; metanephros; and neural retina. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to human RASSF1 (Ras association domain family member 1). [provided by Alliance of Genome Resources, Jul 2025]
9
107428752
107439460
Mouse
257
symbol , old_gene_name , PhenoGen , description , old_gene_symbol
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
Involved in positive regulation of neural precursor cell proliferation and positive regulation of neurogenesis. Predicted to be located in centrosome; cytosol; and spindle pole. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and respiratory