Rassf10 (Ras association (RalGDS/AF-6) domain family (N-terminal) member 10) - Rat Genome Database

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Gene: Rassf10 (Ras association (RalGDS/AF-6) domain family (N-terminal) member 10) Mus musculus
Analyze
Symbol: Rassf10
Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
RGD ID: 1320411
MGI Page MGI
Description: Involved in positive regulation of neural precursor cell proliferation and positive regulation of neurogenesis. Predicted to be located in cytoplasm and cytoskeleton. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and respiratory system. Orthologous to human RASSF10 (Ras association domain family member 10).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4632411J06Rik; ras association domain-containing protein 10
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397112,553,169 - 112,556,665 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7112,553,169 - 112,556,664 (+)EnsemblGRCm39 Ensembl
GRCm387112,953,962 - 112,957,458 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7112,953,962 - 112,957,457 (+)EnsemblGRCm38mm10GRCm38
MGSCv377120,097,476 - 120,100,972 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367112,745,143 - 112,748,627 (+)NCBIMGSCv36mm8
Celera7112,927,035 - 112,930,530 (+)NCBICelera
Cytogenetic Map7F1NCBI
cM Map759.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:19706712   PMID:21267068   PMID:22008794   PMID:26073538  
PMID:29490266   PMID:32047266   PMID:32423821   PMID:34709416  


Genomics

Comparative Map Data
Rassf10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397112,553,169 - 112,556,665 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7112,553,169 - 112,556,664 (+)EnsemblGRCm39 Ensembl
GRCm387112,953,962 - 112,957,458 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7112,953,962 - 112,957,457 (+)EnsemblGRCm38mm10GRCm38
MGSCv377120,097,476 - 120,100,972 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367112,745,143 - 112,748,627 (+)NCBIMGSCv36mm8
Celera7112,927,035 - 112,930,530 (+)NCBICelera
Cytogenetic Map7F1NCBI
cM Map759.13NCBI
RASSF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381113,009,316 - 13,012,119 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1113,009,316 - 13,012,119 (+)EnsemblGRCh38hg38GRCh38
GRCh371113,030,863 - 13,033,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361112,987,272 - 12,989,223 (+)NCBINCBI36Build 36hg18NCBI36
Celera1113,156,837 - 13,158,788 (+)NCBICelera
Cytogenetic Map11p15.3NCBI
HuRef1112,711,157 - 12,713,839 (+)NCBIHuRef
CHM1_11113,029,962 - 13,032,655 (+)NCBICHM1_1
T2T-CHM13v2.01113,101,893 - 13,104,695 (+)NCBIT2T-CHM13v2.0
Rassf10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81176,492,814 - 176,498,127 (+)NCBIGRCr8
mRatBN7.21167,058,277 - 167,063,591 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1167,058,099 - 167,063,572 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1175,393,146 - 175,398,473 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,579,221 - 182,584,546 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01175,274,589 - 175,279,904 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01177,764,177 - 177,769,531 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1177,764,445 - 177,765,968 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01184,738,965 - 184,744,283 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41170,752,114 - 170,755,375 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11170,840,261 - 170,874,816 (+)NCBI
Celera1164,929,946 - 164,935,321 (+)NCBICelera
Cytogenetic Map1q33NCBI
Rassf10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541428,405,289 - 28,406,794 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541428,405,024 - 28,407,734 (+)NCBIChiLan1.0ChiLan1.0
RASSF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2915,454,309 - 15,458,146 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11115,417,408 - 15,421,123 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01113,176,035 - 13,179,744 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11112,868,573 - 12,871,345 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1112,868,816 - 12,870,339 (+)Ensemblpanpan1.1panPan2
RASSF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12135,984,334 - 35,986,358 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2135,984,551 - 35,986,918 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2135,488,889 - 35,490,538 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02136,867,957 - 36,869,606 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2136,868,018 - 36,869,514 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12136,127,204 - 36,128,852 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02136,303,760 - 36,305,412 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02136,592,068 - 36,593,718 (+)NCBIUU_Cfam_GSD_1.0
Rassf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494749,503,874 - 49,507,556 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365285,539,742 - 5,541,262 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365285,536,775 - 5,541,485 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASSF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl246,336,886 - 46,338,394 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1246,332,888 - 46,340,347 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2249,727,233 - 49,748,330 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RASSF10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1151,829,478 - 51,833,606 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl151,830,656 - 51,832,182 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038149,423,657 - 149,426,474 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rassf10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247665,007,442 - 5,008,947 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247665,007,240 - 5,012,264 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rassf10
163 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:531
Count of miRNA genes:410
Interacting mature miRNAs:462
Transcripts:ENSMUST00000058681, ENSMUST00000182858
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787143137119485380Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105250663139250811Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105350008139350008Mouse
13524524Bodwtq6_mbody wweight QTL 6 (mouse)7107245693113055693Mouse
4141056Lskcn2_mLSK cell number 2 (mouse)Not determined108482996118693530Mouse
35673311Ari6_mantibody response to influenza 6, day 15, IgG2b (mouse)7108699207115099235Mouse
25394557Skmw64_mskeletal muscle weight 64, soleus (mouse)7108715780114592736Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000182858   ⟹   ENSMUSP00000138103
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7112,553,169 - 112,556,664 (+)Ensembl
GRCm38.p6 Ensembl7112,953,962 - 112,957,457 (+)Ensembl
RefSeq Acc Id: NM_175279   ⟹   NP_780488
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397112,553,169 - 112,556,665 (+)NCBI
GRCm387112,953,962 - 112,957,458 (+)ENTREZGENE
MGSCv377120,097,476 - 120,100,972 (+)RGD
Celera7112,927,035 - 112,930,530 (+)RGD
cM Map7 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_780488   ⟸   NM_175279
- UniProtKB: Q8C0D3 (UniProtKB/Swiss-Prot),   Q05AF4 (UniProtKB/Swiss-Prot),   Q8K340 (UniProtKB/Swiss-Prot),   Q8BL43 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000138103   ⟸   ENSMUST00000182858
Protein Domains
Ras-associating

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BL43-F1-model_v2 AlphaFold Q8BL43 1-508 view protein structure

Promoters
RGD ID:8665269
Promoter ID:EPDNEW_M10665
Type:multiple initiation site
Name:Rassf10_1
Description:Mus musculus Ras association (RalGDS/AF-6) domain family (N-terminal)member 10 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387112,953,982 - 112,954,042EPDNEW
RGD ID:6841934
Promoter ID:MM_KWN:52342
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4
Transcripts:ENSMUST00000058681,   NM_175279
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367120,097,274 - 120,097,774 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1925998 AgrOrtholog
Ensembl Genes ENSMUSG00000098132 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000182858 ENTREZGENE
  ENSMUST00000182858.2 UniProtKB/Swiss-Prot
InterPro N-RASSF UniProtKB/Swiss-Prot
  RA_dom UniProtKB/Swiss-Prot
  RASSF10_RA UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report mmu:78748 UniProtKB/Swiss-Prot
MGD MGI:1925998 ENTREZGENE
NCBI Gene 78748 ENTREZGENE
PANTHER PTHR15286 UniProtKB/Swiss-Prot
  PTHR15286:SF13 UniProtKB/Swiss-Prot
PhenoGen Rassf10 PhenoGen
PROSITE PS50200 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot
UniProt Q05AF4 ENTREZGENE
  Q8BL43 ENTREZGENE
  Q8C0D3 ENTREZGENE
  Q8K340 ENTREZGENE
  RASFA_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q05AF4 UniProtKB/Swiss-Prot
  Q8C0D3 UniProtKB/Swiss-Prot
  Q8K340 UniProtKB/Swiss-Prot