Lrp5 Gene Search Result

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

Advanced Search (OLGA)

Genes search result for Mus musculus
(View Results for all Objects and Ontologies)

3 records found for search term Lrp5

Refine Term:

Assembly:

Chr

Sort By:

Export

RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1319618	Lrp5	low density lipoprotein receptor-related protein 5	Enables Wnt receptor activity and Wnt-protein binding activity. Involved in several processes, including cell surface receptor signaling pathway; osteoblast development; and positive regulation of osteoblast differentiation. Acts upstream of or within several processes, including embryonic morphogen ... (more) esis; mammary gland development; and vasculature development. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Used to study exudative vitreoretinopathy and osteoporosis-pseudoglioma syndrome. Human ortholog(s) of this gene implicated in autosomal dominant polycystic kidney disease; bone remodeling disease (multiple); eye disease (multiple); osteoporosis-pseudoglioma syndrome; and polycystic liver disease (multiple). Orthologous to human LRP5 (LDL receptor related protein 5). [provided by Alliance of Genome Resources, Jul 2025]	19	3634825	3736574	Mouse	525	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1558526	Fzd8	frizzled class receptor 8	Enables several functions, including PDZ domain binding activity; Wnt receptor activity; and Wnt-protein binding activity. Involved in Wnt signaling pathway. Acts upstream of or within several processes, including T cell differentiation in thymus; canonical Wnt signaling pathway; and positive regula ... (more) tion of JUN kinase activity. Located in plasma membrane. Part of Wnt-Frizzled-LRP5/6 complex. Is active in neuronal dense core vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human FZD8 (frizzled class receptor 8). [provided by Alliance of Genome Resources, Jul 2025]	18	9212856	9216201	Mouse	195	description	gene, protein-coding, VALIDATED [RefSeq]
1319984	Wnt9b	wingless-type MMTV integration site family, member 9B	Enables co-receptor binding activity and signaling receptor binding activity. Acts upstream of or within several processes, including Wnt signaling pathway; chordate embryonic development; and kidney development. Predicted to be located in extracellular region. Predicted to be part of Wnt-Frizzled-< ... (more) span style='font-weight:700;'>LRP5/6 complex. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; epithelium; genitourinary system; heart; and surface ectoderm. Orthologous to human WNT9B (Wnt family member 9B). [provided by Alliance of Genome Resources, Jul 2025]	11	103618188	103666098	Mouse	140	description	gene, protein-coding, VALIDATED [RefSeq]