| 736305 | Lgals3 | lectin, galactose binding, soluble 3 | Predicted to enable several functions, including IgE binding activity; advanced glycation end-product receptor activity; and signaling receptor binding activity. Involved in negative regulation of T cell receptor signaling pathway; negative regulation of endocytosis; and negative regulation of lymph ocyte activation. Acts upstream of or within extracellular matrix organization and skeletal system development. Located in several cellular components, including external side of plasma membrane; glial cell projection; and immunological synapse. Is active in cornified envelope. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; skeleton; and skin. Used to study steatotic liver disease. Human ortholog(s) of this gene implicated in asthma. Orthologous to human LGALS3 (galectin 3). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 47611317 | 47623624 | Mouse | 531 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 734457 | Lgals3bp | lectin, galactoside-binding, soluble, 3 binding protein | Predicted to enable scavenger receptor activity. Predicted to be involved in cell adhesion and vesicle-mediated transport. Located in extracellular space. Is expressed in several structures, including brain; genitourinary system; gut; integumental system; and liver and biliary system. Orthologous to human LGALS3BP (galectin 3 binding protein). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 118283573 | 118292787 | Mouse | 194 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 10868 | Lgals9 | lectin, galactose binding, soluble 9 | Enables several functions, including carbohydrate binding activity; galactoside binding activity; and protein serine/threonine kinase activator activity. Involved in several processes, including regulation of cytokine production; regulation of defense response; and regulation of leukocyte activation . Located in cytoplasm and nucleus. Is expressed in several structures, including cardiovascular system; hemolymphoid system; intestine; liver; and metanephros. Orthologous to several human genes including LGALS9 (galectin 9). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 78853805 | 78875750 | Mouse | 250 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |