Ercc4 Gene Search Result

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3 records found for search term Ercc4

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1312518	Ercc4	excision repair cross-complementing rodent repair deficiency, complementation group 4	Enables TFIID-class transcription factor complex binding activity and promoter-specific chromatin binding activity. Acts upstream of or within DNA repair; UV protection; and regulation of autophagy. Predicted to be located in chromosome, telomeric region and nucleus. Predicted to be part of ERCC4 ... (more) yle='font-weight:700;'>ERCC4-ERCC1 complex and nucleotide-excision repair factor 1 complex. Is expressed in central nervous system and retina. Used to study xeroderma pigmentosum group F. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group Q; XFE progeroid syndrome; pancreatic cancer; polyneuropathy due to drug; and xeroderma pigmentosum (multiple). Orthologous to human ERCC4 (ERCC excision repair 4, endonuclease catalytic subunit). [provided by Alliance of Genome Resources, Jul 2025]	16	12927600	12969873	Mouse	250	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
732969	Xrcc1	X-ray repair complementing 1	Contributes to 3' overhang single-stranded DNA endodeoxyribonuclease activity. Involved in DNA metabolic process and negative regulation of protection from non-homologous end joining at telomere. Acts upstream of or within DNA repair and hippocampus development. Located in chromosome, telomeric regi ... (more) on. Part of ERCC4-ERCC1 complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); carcinoma (multiple); central nervous system cancer (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Orthologous to human XRCC1 (X-ray repair cross complementing 1). [provided by Alliance of Genome Resources, Apr 2025]	7	24246124	24272863	Mouse	495	description	gene, protein-coding, VALIDATED [RefSeq]
1550337	Xrcc4	X-ray repair complementing 4	Contributes to 3' overhang single-stranded DNA endodeoxyribonuclease activity. Involved in double-strand break repair via nonhomologous end joining; negative regulation of protection from non-homologous end joining at telomere; and telomeric DNA-containing double minutes formation. Acts upstream of ... (more) or within several processes, including DNA metabolic process; hemopoiesis; and response to X-ray. Located in chromosome, telomeric region. Part of DNA-dependent protein kinase-DNA ligase 4 complex and ERCC4-ERCC1 complex. Is expressed in head; heart; and trunk. Human ortholog(s) of this gene implicated in multiple myeloma; salivary gland adenoid cystic carcinoma; and salivary gland carcinoma. Orthologous to human XRCC4 (X-ray repair cross complementing 4). [provided by Alliance of Genome Resources, Jul 2025]	13	89997033	90237727	Mouse	242	description	gene, protein-coding, VALIDATED [RefSeq]