Cck Gene Search Result

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6 records found for search term Cck

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
10298	Cck	cholecystokinin	This gene encodes a member of the gastrin/cholecystokinin family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded peptides have been shown to regulate gastric ... (more) acid secretion and food intake. A sulfated form of cholecystokinin-8 may modulate neuronal activity in the brain. Homozygous knockout mice for this gene exhibit impaired insulin secretion, enhanced insulin sensitivity, and resistance to obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]	9	121318890	121324728	Mouse	257	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1319358	Ripk2	receptor (TNFRSF)-interacting serine-threonine kinase 2	This gene encodes a member of the receptor-interacting protein family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain, and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent ac ... (more) tivator of nuclear factor kappa B and inducer of apoptosis in response to various stimuli. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]	4	16122740	16163674	Mouse	324	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
10299	Cckar	cholecystokinin A receptor	Predicted to enable cholecystokinin receptor activity. Acts upstream of or within axonogenesis; forebrain development; and neuron migration. Predicted to be located in several cellular components, including endosome; nucleoplasm; and terminal bouton. Predicted to be active in plasma membrane. Is exp ... (more) ressed in several structures, including brain; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in obesity. Orthologous to human CCKAR (cholecystokinin A receptor). [provided by Alliance of Genome Resources, Jul 2025]	5	53855827	53865046	Mouse	153	symbol , old_gene_name , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
10300	Cckbr	cholecystokinin B receptor	This gene encodes a multipass transmembrane receptor protein expressed in the central nervous system and gastrointestinal tract. Cholecystokinin and gastrin bind to the encoded protein to stimulate gastric acid secretion and mucosal growth in the gastrointestinal tract, and anxiety, pain sensation a ... (more) nd memory in the brain. Mice lacking the encoded protein exhibit an increase in the basal gastric pH and gastrin levels in the bloodstream as well as mild hypocalcemia, secondary hyperparathyroidism and increased bone resorption. [provided by RefSeq, Apr 2015]	7	105075201	105085546	Mouse	234	symbol , old_gene_name , PhenoGen , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1614323	Ptk7	PTK7 protein tyrosine kinase 7	Acts upstream of or within several processes, including cochlea morphogenesis; heart development; and morphogenesis of an epithelium. Located in cell-cell junction and plasma membrane. Is expressed in several structures, including alimentary system; nervous system; paraxial mesenchyme; reproductive ... (more) system; and sensory organ. Orthologous to human PTK7 (protein tyrosine kinase 7 (inactive)). [provided by Alliance of Genome Resources, Jul 2025]	17	46875377	46940975	Mouse	178	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1552437	Ccl28	C-C motif chemokine ligand 28	Enables chemokine activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide; cell chemotaxis; and killing of cells of another organism. Acts upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be active in extracellular s ... (more) pace. Predicted to colocalize with secretory granule. Orthologous to human CCL28 (C-C motif chemokine ligand 28). [provided by Alliance of Genome Resources, Apr 2025]	13	120085355	120115895	Mouse	137	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]