| 1552388 | Acaca | acetyl-Coenzyme A carboxylase alpha | Enables acetyl-CoA carboxylase activity. Involved in acetyl-CoA metabolic process; fatty acid biosynthetic process; and protein homotetramerization. Acts upstream of or within several processes, including cellular response to prostaglandin E stimulus; lipid homeostasis; and tissue homeostasis. Locat ed in cytosol. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human ACACA (acetyl-CoA carboxylase alpha). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 84020461 | 84292477 | Mouse | 695 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1550489 | Prkaa1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | Enables AMP-activated protein kinase activity; chromatin binding activity; and histone H2BS36 kinase activity. Involved in several processes, including negative regulation of TORC1 signaling; regulation of organelle organization; and regulation of primary metabolic process. Acts upstream of or withi n several processes, including cellular response to prostaglandin E stimulus; positive regulation of skeletal muscle tissue development; and regulation of macromolecule metabolic process. Located in several cellular components, including axon; dendrite; and neuronal cell body. Is active in chromatin. Is expressed in several structures, including brain; dorsal root ganglion; early conceptus; liver; and spinal cord. Human ortholog(s) of this gene implicated in Huntington's disease; breast cancer; and colon cancer. Orthologous to human PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2025] | 15 | 5172641 | 5211380 | Mouse | 704 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 730889 | Prkaa2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | Enables AMP-activated protein kinase activity; chromatin binding activity; and histone H2BS36 kinase activity. Involved in several processes, including regulation of autophagy; regulation of organelle organization; and regulation of protein modification process. Acts upstream of or within several pr ocesses, including cellular response to prostaglandin E stimulus; cellular response to xenobiotic stimulus; and response to muscle activity. Located in several cellular components, including cytoplasmic stress granule; dendrite; and neuronal cell body. Is active in cytosol. Is expressed in several structures, including brain; genitourinary system; gut; lung; and spinal cord. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 104886846 | 104967095 | Mouse | 550 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |