Sparc Gene Search Result

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11 records found for search term Sparc

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
731035	SPARC	secreted protein acidic and cysteine rich	This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression ... (more) but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2015]	5	151661096	151686915	Human	500	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
12910636	CLMAT3	colorectal liver metastasis associated transcript 3	INTERACTS WITH triclosan	5	151676945	151687910	Human	1	old_gene_symbol	gene, ncrna, VALIDATED [RefSeq]
736595	SPARCL1	SPARC like 1	Predicted to enable calcium ion binding activity; collagen binding activity; and extracellular matrix binding activity. Predicted to be involved in regulation of synapse organization. Located in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]	4	87473335	87529376	Human	143	symbol , old_gene_name , COSMIC , name , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]
16562821	AC011374.1	novel transcript, antisense to SPARC		5	151637940	151655449	Human		name	gene, ncrna, MODEL [RefSeq]
1348217	SMOC1	SPARC related modular calcium binding 1	This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided ... (more) by RefSeq, Mar 2011]	14	69879416	70032366	Human	270	old_gene_name , name	gene, protein-coding, REVIEWED [RefSeq]
1315436	SMOC2	SPARC related modular calcium binding 2	This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can ... (more) stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]	6	168441184	168667992	Human	262	old_gene_name , name , description	gene, protein-coding, REVIEWED [RefSeq]
1322984	SPOCK1	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1	This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSe ... (more) q, Jul 2008]	5	136975298	137499326	Human	135	old_gene_name , name	gene, protein-coding, REVIEWED [RefSeq]
1318416	SPOCK2	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2	This gene encodes a protein which binds with glycosaminoglycans to form part of the extracellular matrix. The protein contains thyroglobulin type-1, follistatin-like, and calcium-binding domains, and has glycosaminoglycan attachment sites in the acidic C-terminal region. Three alternatively spliced ... (more) transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]	10	72059034	72089032	Human	97	old_gene_name , name	gene, protein-coding, REVIEWED [RefSeq]
1313840	SPOCK3	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3	This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively splice ... (more) d transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]	4	166733384	167234945	Human	79	old_gene_name , name	gene, protein-coding, REVIEWED [RefSeq]
151673779	SPARCL1-AS1	SPARCL1 antisense RNA 1		4	87520221	87526495	Human		symbol , GTEx , COSMIC , name , Human Proteome Map	gene, ncrna, MODEL [RefSeq]
16571176	MIR34BHG	MIR34B and MIR34C host gene	Predicted to be involved in miRNA-mediated post-transcriptional gene silencing. [provided by Alliance of Genome Resources, Jul 2025]	11	111510602	111513888	Human	2	old_gene_symbol	gene, ncrna, VALIDATED [RefSeq]