SPOCK1 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1) - Rat Genome Database

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Gene: SPOCK1 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1) Homo sapiens
Analyze
Symbol: SPOCK1
Name: SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1
RGD ID: 1322984
HGNC Page HGNC:11251
Description: Enables calcium ion binding activity; cysteine-type endopeptidase inhibitor activity; and metalloendopeptidase inhibitor activity. Involved in negative regulation of cell-substrate adhesion and negative regulation of neuron projection development. Located in extracellular space. Implicated in hepatocellular carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: FLJ37170; SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1; sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican); sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1; SPOCK; TESTICAN; testican-1; TIC1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385136,975,298 - 137,499,326 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5136,975,298 - 137,598,379 (-)EnsemblGRCh38hg38GRCh38
GRCh375136,310,987 - 136,835,015 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365136,338,886 - 136,862,917 (-)NCBINCBI36Build 36hg18NCBI36
Build 345136,338,887 - 136,862,894NCBI
Celera5132,435,878 - 132,959,945 (-)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5131,499,446 - 132,023,226 (-)NCBIHuRef
CHM1_15135,743,638 - 136,267,703 (-)NCBICHM1_1
T2T-CHM13v2.05137,497,979 - 138,022,024 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Microcephaly  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. MiR-139-5p, miR-940 and miR-193a-5p inhibit the growth of hepatocellular carcinoma by targeting SPOCK1. Li P, etal., J Cell Mol Med. 2019 Apr;23(4):2475-2488. doi: 10.1111/jcmm.14121. Epub 2019 Feb 1.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7507743   PMID:8389704   PMID:8626787   PMID:9181134   PMID:9272383   PMID:9323035   PMID:9545645   PMID:11131125   PMID:11355883   PMID:11751414   PMID:12477932   PMID:12810672  
PMID:12853036   PMID:14511383   PMID:14702039   PMID:15372022   PMID:16596217   PMID:19282985   PMID:19322201   PMID:20379614   PMID:21873635   PMID:23022495   PMID:23873022   PMID:23897914  
PMID:24134845   PMID:25623055   PMID:26077618   PMID:26138584   PMID:26496610   PMID:26638890   PMID:27108836   PMID:27486308   PMID:27626636   PMID:27889608   PMID:28103946   PMID:28281964  
PMID:28486750   PMID:28534948   PMID:28653880   PMID:28659612   PMID:28869894   PMID:28940639   PMID:29233721   PMID:29315764   PMID:29461591   PMID:30575818   PMID:30825234   PMID:31478239  
PMID:31586073   PMID:32296183   PMID:32555336   PMID:33012508   PMID:33090888   PMID:33293473   PMID:33321927   PMID:33517826   PMID:33884883   PMID:34156309   PMID:34855159   PMID:35221802  
PMID:35462225   PMID:35696571   PMID:36611136   PMID:36766694   PMID:38087364  


Genomics

Comparative Map Data
SPOCK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385136,975,298 - 137,499,326 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5136,975,298 - 137,598,379 (-)EnsemblGRCh38hg38GRCh38
GRCh375136,310,987 - 136,835,015 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365136,338,886 - 136,862,917 (-)NCBINCBI36Build 36hg18NCBI36
Build 345136,338,887 - 136,862,894NCBI
Celera5132,435,878 - 132,959,945 (-)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5131,499,446 - 132,023,226 (-)NCBIHuRef
CHM1_15135,743,638 - 136,267,703 (-)NCBICHM1_1
T2T-CHM13v2.05137,497,979 - 138,022,024 (-)NCBIT2T-CHM13v2.0
Spock1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391357,569,008 - 58,056,194 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1357,569,008 - 58,056,146 (-)EnsemblGRCm39 Ensembl
GRCm381357,421,195 - 57,908,332 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1357,421,195 - 57,908,332 (-)EnsemblGRCm38mm10GRCm38
MGSCv371357,522,556 - 58,009,693 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361357,435,716 - 57,917,898 (-)NCBIMGSCv36mm8
Celera1358,485,985 - 58,970,735 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.5NCBI
Spock1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8176,746,892 - 7,227,034 (+)NCBIGRCr8
mRatBN7.2176,741,504 - 7,221,685 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,742,273 - 7,224,935 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx176,764,172 - 7,241,507 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0178,294,102 - 8,771,565 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,760,562 - 7,237,893 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0177,675,531 - 7,797,863 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl177,675,531 - 7,797,863 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,833,535 - 9,981,069 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41713,198,069 - 13,213,055 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11713,133,516 - 13,212,970 (+)NCBI
Celera176,844,778 - 7,323,370 (+)NCBICelera
Cytogenetic Map17p14NCBI
Spock1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540831,957,882 - 32,465,461 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540831,954,622 - 32,465,463 (-)NCBIChiLan1.0ChiLan1.0
SPOCK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24132,267,651 - 132,785,725 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15130,407,210 - 130,925,284 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05132,372,283 - 132,890,168 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15138,512,523 - 138,730,331 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5138,512,523 - 138,797,416 (-)Ensemblpanpan1.1panPan2
SPOCK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11124,733,290 - 25,013,400 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1124,733,603 - 25,007,376 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1123,482,135 - 23,980,859 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01125,550,901 - 26,073,758 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1125,550,906 - 26,007,073 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11124,288,279 - 24,783,213 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01124,106,169 - 24,605,094 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01124,771,888 - 25,267,226 (-)NCBIUU_Cfam_GSD_1.0
Spock1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213124,975,526 - 125,469,022 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365974,000,400 - 4,156,221 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365974,000,433 - 4,493,920 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPOCK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2139,018,179 - 139,522,593 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12139,018,177 - 139,523,601 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22144,718,318 - 145,255,866 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPOCK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12339,676,750 - 40,192,565 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2339,676,558 - 39,965,037 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603437,701,157 - 38,216,801 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spock1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247339,556,763 - 10,080,703 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247339,556,024 - 10,080,703 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SPOCK1
41 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q23.3-33.2(chr5:130860928-155321811)x3 copy number gain See cases [RCV000051193] Chr5:130860928..155321811 [GRCh38]
Chr5:130196621..154701371 [GRCh37]
Chr5:130224520..154681564 [NCBI36]
Chr5:5q23.3-33.2
pathogenic
GRCh38/hg38 5q31.1-31.2(chr5:133401565-138437038)x1 copy number loss See cases [RCV000052114] Chr5:133401565..138437038 [GRCh38]
Chr5:132737257..137772727 [GRCh37]
Chr5:132765156..137800626 [NCBI36]
Chr5:5q31.1-31.2
pathogenic
GRCh38/hg38 5q31.1-31.2(chr5:135894042-137619032)x1 copy number loss See cases [RCV000052116] Chr5:135894042..137619032 [GRCh38]
Chr5:135229731..136954721 [GRCh37]
Chr5:135257630..136982620 [NCBI36]
Chr5:5q31.1-31.2
pathogenic
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1 copy number loss See cases [RCV000053524] Chr5:106619588..156124387 [GRCh38]
Chr5:105955289..155551397 [GRCh37]
Chr5:105983188..155483975 [NCBI36]
Chr5:5q21.3-33.2
pathogenic
NM_004598.3(SPOCK1):c.774G>A (p.Met258Ile) single nucleotide variant Malignant melanoma [RCV000066632] Chr5:136988576 [GRCh38]
Chr5:136324265 [GRCh37]
Chr5:136352164 [NCBI36]
Chr5:5q31.2
not provided
NM_004598.3(SPOCK1):c.743C>T (p.Ser248Phe) single nucleotide variant Malignant melanoma [RCV000066633] Chr5:136988607 [GRCh38]
Chr5:136324296 [GRCh37]
Chr5:136352195 [NCBI36]
Chr5:5q31.2
not provided
NM_004598.3(SPOCK1):c.612G>A (p.Arg204=) single nucleotide variant Malignant melanoma [RCV000066634] Chr5:136992578 [GRCh38]
Chr5:136328267 [GRCh37]
Chr5:136356166 [NCBI36]
Chr5:5q31.2
not provided
NM_004598.3(SPOCK1):c.590-584G>C single nucleotide variant Lung cancer [RCV000095340] Chr5:136993184 [GRCh38]
Chr5:136328873 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.3(SPOCK1):c.590-955T>A single nucleotide variant Lung cancer [RCV000095341] Chr5:136993555 [GRCh38]
Chr5:136329244 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.3(SPOCK1):c.233-35412T>G single nucleotide variant Lung cancer [RCV000095342] Chr5:137176106 [GRCh38]
Chr5:136511795 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.3(SPOCK1):c.187-93535C>T single nucleotide variant Lung cancer [RCV000095343] Chr5:137360590 [GRCh38]
Chr5:136696279 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.239A>T (p.Asp80Val) single nucleotide variant not provided [RCV000114941] Chr5:137140688 [GRCh38]
Chr5:136476377 [GRCh37]
Chr5:5q31.2
uncertain significance
GRCh38/hg38 5q31.1-31.3(chr5:135297294-140106003)x3 copy number gain See cases [RCV000133750] Chr5:135297294..140106003 [GRCh38]
Chr5:134632984..139485588 [GRCh37]
Chr5:134660883..139465772 [NCBI36]
Chr5:5q31.1-31.3
pathogenic
GRCh38/hg38 5q31.2(chr5:137117353-137434323)x1 copy number loss See cases [RCV000136621] Chr5:137117353..137434323 [GRCh38]
Chr5:136453042..136770012 [GRCh37]
Chr5:136480941..136797911 [NCBI36]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.110A>G (p.Asn37Ser) single nucleotide variant not specified [RCV000202725] Chr5:137498449 [GRCh38]
Chr5:136834138 [GRCh37]
Chr5:5q31.2
benign
GRCh38/hg38 5q23.3-33.2(chr5:129847794-153353546)x3 copy number gain See cases [RCV000138808] Chr5:129847794..153353546 [GRCh38]
Chr5:129183487..152733106 [GRCh37]
Chr5:129211386..152713299 [NCBI36]
Chr5:5q23.3-33.2
pathogenic
GRCh38/hg38 5q31.2(chr5:137051283-137088694)x3 copy number gain See cases [RCV000140353] Chr5:137051283..137088694 [GRCh38]
Chr5:136386972..136424383 [GRCh37]
Chr5:136414871..136452282 [NCBI36]
Chr5:5q31.2
uncertain significance
GRCh38/hg38 5q31.2(chr5:137051283-137117353)x3 copy number gain See cases [RCV000140976] Chr5:137051283..137117353 [GRCh38]
Chr5:136386972..136453042 [GRCh37]
Chr5:136414871..136480941 [NCBI36]
Chr5:5q31.2
likely benign
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3
likely benign
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910)x3 copy number gain See cases [RCV000449349] Chr5:130125085..157574910 [GRCh37]
Chr5:5q23.3-33.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3
pathogenic
GRCh37/hg19 5q31.2(chr5:136667092-137380603)x3 copy number gain See cases [RCV000447839] Chr5:136667092..137380603 [GRCh37]
Chr5:5q31.2
uncertain significance
NC_000005.9:g.(?_86400000)_(154000000_?)del deletion Familial adenomatous polyposis 1 [RCV002231249]|Hereditary cancer-predisposing syndrome [RCV000554476] Chr5:86400000..154000000 [GRCh37]
Chr5:5q14.3-33.2
pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
NM_004598.4(SPOCK1):c.638G>T (p.Trp213Leu) single nucleotide variant Inborn genetic diseases [RCV003275140] Chr5:136992552 [GRCh38]
Chr5:136328241 [GRCh37]
Chr5:5q31.2
uncertain significance
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q31.2(chr5:136394804-136546808)x3 copy number gain not provided [RCV000745187] Chr5:136394804..136546808 [GRCh37]
Chr5:5q31.2
benign
GRCh37/hg19 5q31.2(chr5:136825355-136882278)x0 copy number loss not provided [RCV000745188] Chr5:136825355..136882278 [GRCh37]
Chr5:5q31.2
benign
GRCh37/hg19 5q31.2(chr5:136832009-136858359)x1 copy number loss not provided [RCV000745189] Chr5:136832009..136858359 [GRCh37]
Chr5:5q31.2
benign
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32
uncertain significance
GRCh37/hg19 5q31.2(chr5:136810103-136982225)x3 copy number gain not provided [RCV000849008] Chr5:136810103..136982225 [GRCh37]
Chr5:5q31.2
uncertain significance
GRCh37/hg19 5q31.2(chr5:136543033-136615940)x1 copy number loss not provided [RCV000848566] Chr5:136543033..136615940 [GRCh37]
Chr5:5q31.2
uncertain significance
NC_000005.9:g.136320037_136380192dup duplication Internal malformations [RCV000787458] Chr5:136320037..136380192 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.398T>G (p.Leu133Trp) single nucleotide variant Inborn genetic diseases [RCV003275254] Chr5:137112511 [GRCh38]
Chr5:136448200 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.784C>G (p.Leu262Val) single nucleotide variant Inborn genetic diseases [RCV003275338] Chr5:136988566 [GRCh38]
Chr5:136324255 [GRCh37]
Chr5:5q31.2
uncertain significance
GRCh37/hg19 5q31.2(chr5:136414500-136770840)x1 copy number loss not provided [RCV001005738] Chr5:136414500..136770840 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.313G>A (p.Ala105Thr) single nucleotide variant Microcephaly [RCV001252868] Chr5:137140614 [GRCh38]
Chr5:136476303 [GRCh37]
Chr5:5q31.2
uncertain significance
GRCh37/hg19 5q31.2(chr5:136409875-137739167) copy number loss Microcephaly [RCV001352638] Chr5:136409875..137739167 [GRCh37]
Chr5:5q31.2
pathogenic
NC_000005.9:g.(?_136633338)_(140998481_?)dup duplication PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome [RCV001339088] Chr5:136633338..140998481 [GRCh37]
Chr5:5q31.2-31.3
uncertain significance
GRCh37/hg19 5q31.1-31.2(chr5:132031902-137623639) copy number loss not specified [RCV002053530] Chr5:132031902..137623639 [GRCh37]
Chr5:5q31.1-31.2
pathogenic
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910) copy number gain not specified [RCV002053526] Chr5:130125085..157574910 [GRCh37]
Chr5:5q23.3-33.3
pathogenic
NM_004598.4(SPOCK1):c.204C>G (p.Asn68Lys) single nucleotide variant Inborn genetic diseases [RCV002753496] Chr5:137267038 [GRCh38]
Chr5:136602727 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.107G>A (p.Gly36Asp) single nucleotide variant Inborn genetic diseases [RCV002840755] Chr5:137498452 [GRCh38]
Chr5:136834141 [GRCh37]
Chr5:5q31.2
uncertain significance
GRCh37/hg19 5q31.2(chr5:136409275-136960997)x1 copy number loss not provided [RCV002475525] Chr5:136409275..136960997 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.517G>A (p.Ala173Thr) single nucleotide variant Inborn genetic diseases [RCV002951646] Chr5:137067787 [GRCh38]
Chr5:136403476 [GRCh37]
Chr5:5q31.2
likely benign
NM_004598.4(SPOCK1):c.1241G>C (p.Arg414Thr) single nucleotide variant Inborn genetic diseases [RCV002782648] Chr5:136978733 [GRCh38]
Chr5:136314422 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.392C>T (p.Ser131Leu) single nucleotide variant Inborn genetic diseases [RCV002868657] Chr5:137112517 [GRCh38]
Chr5:136448206 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.419C>T (p.Pro140Leu) single nucleotide variant Inborn genetic diseases [RCV002804751] Chr5:137112490 [GRCh38]
Chr5:136448179 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.754A>G (p.Met252Val) single nucleotide variant Inborn genetic diseases [RCV002826181] Chr5:136988596 [GRCh38]
Chr5:136324285 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.106G>C (p.Gly36Arg) single nucleotide variant Inborn genetic diseases [RCV002744772] Chr5:137498453 [GRCh38]
Chr5:136834142 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.328C>T (p.Arg110Cys) single nucleotide variant Inborn genetic diseases [RCV002748279] Chr5:137140599 [GRCh38]
Chr5:136476288 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.523C>A (p.Leu175Ile) single nucleotide variant Inborn genetic diseases [RCV002748281] Chr5:137067781 [GRCh38]
Chr5:136403470 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.867C>G (p.Asp289Glu) single nucleotide variant Inborn genetic diseases [RCV002836132] Chr5:136988483 [GRCh38]
Chr5:136324172 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.565C>G (p.Pro189Ala) single nucleotide variant Inborn genetic diseases [RCV002897253] Chr5:137067739 [GRCh38]
Chr5:136403428 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.413C>A (p.Pro138His) single nucleotide variant Inborn genetic diseases [RCV003212895] Chr5:137112496 [GRCh38]
Chr5:136448185 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.392C>G (p.Ser131Trp) single nucleotide variant Inborn genetic diseases [RCV003266149] Chr5:137112517 [GRCh38]
Chr5:136448206 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.832G>A (p.Glu278Lys) single nucleotide variant Inborn genetic diseases [RCV003309883] Chr5:136988518 [GRCh38]
Chr5:136324207 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.508A>G (p.Lys170Glu) single nucleotide variant Inborn genetic diseases [RCV003343432] Chr5:137067796 [GRCh38]
Chr5:136403485 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.421G>A (p.Val141Met) single nucleotide variant Inborn genetic diseases [RCV003363354] Chr5:137112488 [GRCh38]
Chr5:136448177 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.721A>G (p.Ile241Val) single nucleotide variant Inborn genetic diseases [RCV003378420] Chr5:136988629 [GRCh38]
Chr5:136324318 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.109A>G (p.Asn37Asp) single nucleotide variant Inborn genetic diseases [RCV003377284] Chr5:137498450 [GRCh38]
Chr5:136834139 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.610C>T (p.Arg204Trp) single nucleotide variant Inborn genetic diseases [RCV003363888] Chr5:136992580 [GRCh38]
Chr5:136328269 [GRCh37]
Chr5:5q31.2
uncertain significance
NM_004598.4(SPOCK1):c.105C>T (p.His35=) single nucleotide variant not provided [RCV003429772] Chr5:137498454 [GRCh38]
Chr5:136834143 [GRCh37]
Chr5:5q31.2
likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2765
Count of miRNA genes:1166
Interacting mature miRNAs:1444
Transcripts:ENST00000282223, ENST00000394945, ENST00000503916, ENST00000505690, ENST00000508642, ENST00000509293, ENST00000509978, ENST00000510405, ENST00000510689, ENST00000515091
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH102718  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,466,388 - 136,466,515UniSTSGRCh37
Build 365136,494,287 - 136,494,414RGDNCBI36
Celera5132,591,329 - 132,591,456RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,654,621 - 131,654,748UniSTS
GeneMap99-GB4 RH Map5519.2UniSTS
RH103418  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,311,170 - 136,311,352UniSTSGRCh37
Build 365136,339,069 - 136,339,251RGDNCBI36
Celera5132,436,061 - 132,436,243RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,499,629 - 131,499,811UniSTS
GeneMap99-GB4 RH Map5519.2UniSTS
SHGC-78900  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,477,835 - 136,478,105UniSTSGRCh37
Build 365136,505,734 - 136,506,004RGDNCBI36
Celera5132,602,780 - 132,603,050RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,666,061 - 131,666,331UniSTS
TNG Radiation Hybrid Map563450.0UniSTS
SHGC-85172  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,313,775 - 136,314,088UniSTSGRCh37
Build 365136,341,674 - 136,341,987RGDNCBI36
Celera5132,438,667 - 132,438,980RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,502,235 - 131,502,548UniSTS
TNG Radiation Hybrid Map563329.0UniSTS
RH120820  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,653,164 - 136,653,443UniSTSGRCh37
Build 365136,681,063 - 136,681,342RGDNCBI36
Celera5132,778,085 - 132,778,364RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,841,385 - 131,841,664UniSTS
TNG Radiation Hybrid Map563550.0UniSTS
RH123159  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,472,798 - 136,473,143UniSTSGRCh37
Build 365136,500,697 - 136,501,042RGDNCBI36
Celera5132,597,741 - 132,598,086RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,661,021 - 131,661,366UniSTS
TNG Radiation Hybrid Map563440.0UniSTS
RH123614  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,321,754 - 136,322,032UniSTSGRCh37
Build 365136,349,653 - 136,349,931RGDNCBI36
Celera5132,446,658 - 132,446,936RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,510,226 - 131,510,504UniSTS
TNG Radiation Hybrid Map563334.0UniSTS
D5S2225E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,676,665 - 136,676,761UniSTSGRCh37
Build 365136,704,564 - 136,704,660RGDNCBI36
Celera5132,801,585 - 132,801,681RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,864,888 - 131,864,984UniSTS
SHGC-106775  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,581,054 - 136,581,385UniSTSGRCh37
Build 365136,608,953 - 136,609,284RGDNCBI36
Celera5132,706,007 - 132,706,338RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,769,309 - 131,769,640UniSTS
TNG Radiation Hybrid Map563503.0UniSTS
SHGC-146899  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,814,596 - 136,814,898UniSTSGRCh37
Build 365136,842,495 - 136,842,797RGDNCBI36
Celera5132,939,548 - 132,939,850RGD
Cytogenetic Map5q31.2UniSTS
HuRef5132,002,810 - 132,003,112UniSTS
TNG Radiation Hybrid Map563618.0UniSTS
bac5202S  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,346,800 - 136,346,982UniSTSGRCh37
Build 365136,374,699 - 136,374,881RGDNCBI36
Celera5132,471,708 - 132,471,890RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,535,277 - 131,535,459UniSTS
bac5202T  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,474,285 - 136,474,575UniSTSGRCh37
Build 365136,502,184 - 136,502,474RGDNCBI36
Celera5132,599,230 - 132,599,520RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,662,514 - 131,662,802UniSTS
bac5208S  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,593,834 - 136,593,961UniSTSGRCh37
Build 365136,621,733 - 136,621,860RGDNCBI36
Celera5132,718,788 - 132,718,915RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,782,090 - 131,782,217UniSTS
SHGC-66131  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,828,236 - 136,828,506UniSTSGRCh37
Build 365136,856,135 - 136,856,405RGDNCBI36
Celera5132,953,186 - 132,953,456RGD
Cytogenetic Map5q31.2UniSTS
HuRef5132,016,448 - 132,016,718UniSTS
TNG Radiation Hybrid Map563643.0UniSTS
SHGC-78948  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,472,916 - 136,473,193UniSTSGRCh37
Build 365136,500,815 - 136,501,092RGDNCBI36
Celera5132,597,859 - 132,598,136RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,661,139 - 131,661,416UniSTS
TNG Radiation Hybrid Map563430.0UniSTS
IB3085  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,313,970 - 136,314,213UniSTSGRCh37
Build 365136,341,869 - 136,342,112RGDNCBI36
Celera5132,438,862 - 132,439,106RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,502,430 - 131,502,674UniSTS
GeneMap99-GB4 RH Map5519.2UniSTS
Whitehead-RH Map5427.6UniSTS
A002R29  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,313,924 - 136,314,173UniSTSGRCh37
Build 365136,341,823 - 136,342,072RGDNCBI36
Celera5132,438,816 - 132,439,066RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,502,384 - 131,502,634UniSTS
GeneMap99-GB4 RH Map5519.2UniSTS
1446  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,311,068 - 136,311,170UniSTSGRCh37
Build 365136,338,967 - 136,339,069RGDNCBI36
Celera5132,435,959 - 132,436,061RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,499,527 - 131,499,629UniSTS
GeneMap99-GB4 RH Map5494.29UniSTS
D5S2429  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,312,678 - 136,312,802UniSTSGRCh37
Build 365136,340,577 - 136,340,701RGDNCBI36
Celera5132,437,569 - 132,437,693RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,501,137 - 131,501,261UniSTS
Whitehead-YAC Contig Map5 UniSTS
L31473  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,685,162 - 136,685,419UniSTSGRCh37
Build 365136,713,061 - 136,713,318RGDNCBI36
Celera5132,810,082 - 132,810,339RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,873,385 - 131,873,642UniSTS
D5S2484  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375136,593,411 - 136,593,510UniSTSGRCh37
Build 365136,621,310 - 136,621,409RGDNCBI36
Celera5132,718,365 - 132,718,464RGD
Cytogenetic Map5q31.2UniSTS
HuRef5131,781,667 - 131,781,766UniSTS
Whitehead-RH Map5427.7UniSTS
Whitehead-YAC Contig Map5 UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 1
Medium 1464 1752 921 70 97 21 2790 1138 3395 248 1021 680 58 1108 1862 1
Low 776 521 413 183 542 73 1541 1035 312 156 381 838 112 96 925
Below cutoff 141 702 319 302 1023 303 21 17 10 13 36 81 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_034127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_004598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC091818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC092270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC106746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC106787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC106809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF231124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI674088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC030691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG704964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI550122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC877120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC877134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000282223   ⟹   ENSP00000282223
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5136,975,300 - 137,267,055 (-)Ensembl
RefSeq Acc Id: ENST00000394945   ⟹   ENSP00000378401
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5136,975,298 - 137,499,326 (-)Ensembl
RefSeq Acc Id: ENST00000503916
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5137,112,494 - 137,598,379 (-)Ensembl
RefSeq Acc Id: ENST00000505690   ⟹   ENSP00000424517
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5137,112,492 - 137,498,594 (-)Ensembl
RefSeq Acc Id: ENST00000508642
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5136,988,553 - 136,993,160 (-)Ensembl
RefSeq Acc Id: ENST00000509293
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5137,267,015 - 137,365,461 (-)Ensembl
RefSeq Acc Id: ENST00000509978
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5136,978,792 - 136,988,837 (-)Ensembl
RefSeq Acc Id: ENST00000510405
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5137,112,435 - 137,313,538 (-)Ensembl
RefSeq Acc Id: ENST00000510689   ⟹   ENSP00000421677
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5136,992,554 - 137,499,299 (-)Ensembl
RefSeq Acc Id: ENST00000515091
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5136,978,454 - 136,979,500 (-)Ensembl
RefSeq Acc Id: ENST00000635347
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5136,992,515 - 137,313,577 (-)Ensembl
RefSeq Acc Id: NM_004598   ⟹   NP_004589
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385136,975,298 - 137,499,326 (-)NCBI
GRCh375136,310,987 - 136,835,018 (-)ENTREZGENE
Build 365136,338,886 - 136,862,917 (-)NCBI Archive
HuRef5131,499,446 - 132,023,226 (-)ENTREZGENE
CHM1_15135,743,638 - 136,267,703 (-)NCBI
T2T-CHM13v2.05137,497,979 - 138,022,024 (-)NCBI
Sequence:
RefSeq Acc Id: NP_004589   ⟸   NM_004598
- Peptide Label: precursor
- UniProtKB: Q8N630 (UniProtKB/Swiss-Prot),   Q59EW0 (UniProtKB/Swiss-Prot),   B3KSW3 (UniProtKB/Swiss-Prot),   Q9UCL8 (UniProtKB/Swiss-Prot),   Q08629 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000424517   ⟸   ENST00000505690
RefSeq Acc Id: ENSP00000282223   ⟸   ENST00000282223
RefSeq Acc Id: ENSP00000421677   ⟸   ENST00000510689
RefSeq Acc Id: ENSP00000378401   ⟸   ENST00000394945
Protein Domains
Kazal-like   Thyroglobulin type-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q08629-F1-model_v2 AlphaFold Q08629 1-439 view protein structure

Promoters
RGD ID:6803575
Promoter ID:HG_KWN:51171
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3
Transcripts:ENST00000394945,   UC003LBO.1
Position:
Human AssemblyChrPosition (strand)Source
Build 365136,862,604 - 136,863,104 (-)MPROMDB
RGD ID:6870664
Promoter ID:EPDNEW_H8497
Type:initiation region
Name:SPOCK1_1
Description:SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385137,499,326 - 137,499,386EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11251 AgrOrtholog
COSMIC SPOCK1 COSMIC
Ensembl Genes ENSG00000152377 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000394945 ENTREZGENE
  ENST00000394945.6 UniProtKB/Swiss-Prot
  ENST00000505690.1 UniProtKB/TrEMBL
  ENST00000510689.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.60.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.800.10 UniProtKB/Swiss-Prot
  EF-hand UniProtKB/Swiss-Prot
GTEx ENSG00000152377 GTEx
HGNC ID HGNC:11251 ENTREZGENE
Human Proteome Map SPOCK1 Human Proteome Map
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  Kazal_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPARC/Testican_Ca-bd-dom UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot
  Thyroglobulin_1_sf UniProtKB/Swiss-Prot
KEGG Report hsa:6695 UniProtKB/Swiss-Prot
NCBI Gene 6695 ENTREZGENE
OMIM 602264 OMIM
PANTHER SPARC OSTEONECTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TESTICAN-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Kazal_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPARC_Ca_bdg UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot
PharmGKB PA36081 PharmGKB
PROSITE KAZAL_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THYROGLOBULIN_1_1 UniProtKB/Swiss-Prot
  THYROGLOBULIN_1_2 UniProtKB/Swiss-Prot
SMART KAZAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00211 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF100895 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47473 UniProtKB/Swiss-Prot
  SSF57610 UniProtKB/Swiss-Prot
UniProt B3KSW3 ENTREZGENE
  D6RAM7_HUMAN UniProtKB/TrEMBL
  D6RB21_HUMAN UniProtKB/TrEMBL
  L8ECB3_HUMAN UniProtKB/TrEMBL
  Q08629 ENTREZGENE
  Q59EW0 ENTREZGENE
  Q8N630 ENTREZGENE
  Q9UCL8 ENTREZGENE
  TICN1_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B3KSW3 UniProtKB/Swiss-Prot
  Q59EW0 UniProtKB/Swiss-Prot
  Q8N630 UniProtKB/Swiss-Prot
  Q9UCL8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-02-27 SPOCK1  SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1  SPOCK1  SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1  Symbol and/or name change 5135510 APPROVED
2016-08-16 SPOCK1  SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1  SPOCK1  sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1  Symbol and/or name change 5135510 APPROVED