Rgs14 Gene Search Result

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2 records found for search term Rgs14

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
733515	RGS14	regulator of G protein signaling 14	This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of act ... (more) ivated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]	5	177357924	177372596	Human	167	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1343291	RGS16	regulator of G protein signaling 16	The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by Ref ... (more) Seq, Jul 2008]	1	182598623	182604389	Human	263	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]