| 1352691 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been impl icated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016] | 3 | 179148126 | 179240093 | Human | 1575 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 16554317 | PIK3CA-DT | PIK3CA divergent transcript | | 3 | 179101371 | 179147973 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16555796 | AP000547.1 | phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA) pseudogene | | | | | Human | | name | gene, unprocessed_pseudogene |
| 1607055 | APPL1 | adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 | The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA IK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008] | 3 | 57227729 | 57273471 | Human | 245 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1604816 | MTFP1 | mitochondrial fission process 1 | MTP18 is a mitochondrial protein and downstream target of the phosphatidylinositol 3-kinase (see PIK3CA, MIM 171834) signaling pathway that plays a role in cell viability and mitochondrial dynamics (Tondera et al., 2004 [PubMed 15155745]).[supplied by OMIM, Mar 2008] | 22 | 30425768 | 30429054 | Human | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |