| 737392 | PDC | phosducin | This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] | 1 | 186443566 | 186461114 | Human | 24 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 14974272 | PDC-AS1 | PDC antisense RNA 1 | | 1 | 186435161 | 186470291 | Human | | symbol , COSMIC , name , ensembl_full_name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1346850 | PNKD | PNKD metallo-beta-lactamase domain containing | This gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non-kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] | 2 | 218270519 | 218346793 | Human | 176 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 735273 | DLAT | dihydrolipoamide S-acetyltransferase | This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of t his gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.[provided by RefSeq, Oct 2009] | 11 | 112025408 | 112064404 | Human | 305 | description , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 735514 | PDCL | phosducin like | Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling b y binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008] | 9 | 122818097 | 122828588 | Human | 75 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1323231 | PDCD1 | programmed cell death 1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiatio n of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | 2 | 241849884 | 241858894 | Human | 256 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 733734 | PDCD2 | programmed cell death 2 | This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on t his protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010] | 6 | 170575295 | 170584637 | Human | 102 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 732159 | PDCD4 | programmed cell death 4 | This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010] | 10 | 110871928 | 110900006 | Human | 301 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1321536 | PDCD5 | programmed cell death 5 | This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by in hibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010] | 19 | 32581190 | 32587453 | Human | 108 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1322592 | PDCD6 | programmed cell death 6 | This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-ind uced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012] | 5 | 271646 | 314974 | Human | 176 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1319039 | PDCD7 | programmed cell death 7 | This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010] | 15 | 65117379 | 65133808 | Human | 69 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1344096 | PDCL2 | phosducin like 2 | This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G pro teins. [provided by RefSeq, Jul 2008] | 4 | 55556519 | 55592245 | Human | 26 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320124 | PDCL3 | phosducin like 3 | This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G pro teins. [provided by RefSeq, Jul 2008] | 2 | 100562993 | 100576739 | Human | 108 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1351056 | PDCD10 | programmed cell death 10 | This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, an d is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] | 3 | 167683298 | 167734892 | Human | 250 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1354347 | PDCD11 | programmed cell death 11 | PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplie d by OMIM, Oct 2008] | 10 | 103396626 | 103446294 | Human | 100 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1601844 | PDCD2L | programmed cell death 2 like | Predicted to be involved in apoptotic process. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 34404399 | 34426168 | Human | 62 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 16555472 | PDCD2P1 | PDCD2 pseudogene 1 | | 9 | 113850836 | 113851635 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 617301281 | PDCD2P2 | PDCD2 pseudogene 2 | | | | | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 8549004 | PDCD5P1 | programmed cell death 5 pseudogene 1 | | 12 | 19413152 | 19413588 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 8549094 | PDCD5P2 | programmed cell death 5 pseudogene 2 | | 5 | 76280916 | 76281401 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 68505 | PDCD6IP | programmed cell death 6 interacting protein | This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the prod uct of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012] | 3 | 33798630 | 33869703 | Human | 225 | symbol , old_gene_name , COSMIC , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 38613548 | PDCD6P1 | PDCD6 pseudogene 1 | | 5 | 1597557 | 1634005 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 8552525 | PDCL2P1 | PDCL2 pseudogene 1 | | X | 23198318 | 23198710 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 10400832 | PDCL2P2 | PDCL2 pseudogene 2 | | 11 | 65160194 | 65160382 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1354070 | PDCL3P1 | PDCL3 pseudogene 1 | | 8 | 60387201 | 60388192 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5684196 | PDCL3P2 | PDCL3 pseudogene 2 | | 8 | 101871595 | 101872579 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7174896 | PDCL3P3 | PDCL3 pseudogene 3 | | 3 | 17877266 | 17878196 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7174794 | PDCL3P4 | PDCL3 pseudogene 4 | INTERACTS WITH 2-hydroxypropanoic acid; acrylamide; lipopolysaccharide | 3 | 101712434 | 101713416 | Human | 5 | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 7174938 | PDCL3P5 | PDCL3 pseudogene 5 | | 6 | 150827625 | 150828620 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7174871 | PDCL3P6 | PDCL3 pseudogene 6 | | 1 | 52179815 | 52180694 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7174981 | PDCL3P7 | PDCL3 pseudogene 7 | | 12 | 66275933 | 66276649 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, MODEL [RefSeq] |
| 1314998 | PDCD1LG2 | programmed cell death 1 ligand 2 | Involved in negative regulation of activated T cell proliferation; negative regulation of interleukin-10 production; and negative regulation of type II interferon production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of pulmonar y tuberculosis. [provided by Alliance of Genome Resources, Jul 2025] | 9 | 5510531 | 5571282 | Human | 87 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 38653307 | PDCD6-DT | PDCD6 divergent transcript | | 5 | 269556 | 271524 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 7241979 | PDCD4-AS1 | PDCD4 antisense RNA 1 | INTERACTS WITH 17beta-estradiol; aristolochic acid A; benzo[a]pyrene | 10 | 110868890 | 110870904 | Human | 18 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, PREDICTED [RefSeq] |
| 8549097 | PDCD6IPP1 | PDCD6IP pseudogene 1 | | 15 | 22727104 | 22744699 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 8549005 | PDCD6IPP2 | PDCD6IP pseudogene 2 | | 15 | 28789834 | 28856574 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, PROVISIONAL [RefSeq] |
| 15091047 | PDCD6-AHRR | PDCD6-AHRR readthrough (NMD candidate) | Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Predicted to be located in ER to Golgi transport vesicle membrane. [provided by Alliance of Genome Resources, Jul 2025] | 5 | 271646 | 438285 | Human | 7 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 38603561 | PDCD6IP-DT | PDCD6IP divergent transcript | | 3 | 33793644 | 33798519 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 735964 | DECR2 | 2,4-dienoyl-CoA reductase 2 | Enables 2,4-dienoyl-CoA reductase (NADPH) activity and trans-2-enoyl-CoA reductase (NADPH) activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in cytosol and peroxisomal membrane. Predicted to be active in peroxisome. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 401885 | 412482 | Human | 137 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 736986 | NPHS2 | NPHS2 stomatin family member, podocin | This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] | 1 | 179550539 | 179575948 | Human | 319 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 731380 | AIFM1 | apoptosis inducing factor mitochondria associated 1 | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentat ion. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015] | X | 130129362 | 130165841 | Human | 688 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1320179 | MRPS30 | mitochondrial ribosomal protein S30 | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryot ic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that is similar to the chicken pro-apoptotic protein p52. Transcript variants using alternative promoters or polyA sites have been mentioned in the literature but the complete description of these sequences is not available. [provided by RefSeq, Jul 2008] | 5 | 44808947 | 44815514 | Human | 82 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1320536 | AVEN | apoptosis and caspase activation inhibitor | Involved in negative regulation of apoptotic process. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025] | 15 | 33851781 | 34075325 | Human | 94 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1352883 | CSN2 | casein beta | This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and kappa casein proteins acting together form spherical micelles which bind within them important dietary minerals, such as calcium and phosphorous. In addition, the C-terminal 14 aa of the protein has antimicrobial activity, especially in preterm milk, displaying antibacterial activity against S. aureus and Y. enterocolitica. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2020] | 4 | 69955256 | 69965728 | Human | 72 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1605684 | CD274 | CD274 molecule | This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] | 9 | 5450542 | 5470554 | Human | 325 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1604616 | ASIC4 | acid sensing ion channel subunit family member 4 | This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012] | 2 | 219507093 | 219538772 | Human | 68 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1602881 | PDPR | pyruvate dehydrogenase phosphatase regulatory subunit | Pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate and links glycolysis to the tricarboxylic acid cycle and fatty acid synthesis. The dephosphorylation and reactivation of PDC is catalyz ed by pyruvate dehydrogenase phosphatase (PDP). The dimeric PDP has a catalytic subunit and a regulatory subunit. This gene encodes the FAD-containing regulatory subunit of PDP. The encoded protein acts to decrease the sensitivity of the PDP catalytic subunit to magnesium ions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017] | 16 | 70113626 | 70163427 | Human | 71 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1348641 | AHRR | aryl hydrocarbon receptor repressor | The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively sp liced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011] | 5 | 321714 | 438285 | Human | 201 | ensembl_gene_symbol , ensembl_full_name | gene, protein-coding, REVIEWED [RefSeq] |
| 16567698 | LNPPS | lncRNA PDCD5 and p53 scaffold | | | | | Human | | name | gene, lncrna |
| 155882988 | LNPPS | lncRNA PDCD5 and p53 scaffold | | | | | Human | | name | gene, ncrna |
| 1602474 | PGCKA1 | PDCD10 and GCKIII kinases associated 1 | INVOLVED IN regulation of cell cycle; ASSOCIATED WITH cholestasis; FOUND IN cell periphery; INTERACTS WITH 17beta-estradiol; 3-methylcholanthrene; 4,4'-sulfonyldiphenol | 4 | 37453255 | 37593510 | Human | 52 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 16562657 | AC124944.2 | programmed cell death 6 (PDCD6) pseudogene | | | | | Human | | name | gene, transcribed_unprocessed_pseudogene |
| 16561524 | AC126177.6 | programmed cell death 2 (PDCD2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16570003 | AC233280.19 | programmed cell death 6 (PDCD6) pseudogene | | | | | Human | | name | gene, unprocessed_pseudogene |
| 16559702 | AC087272.1 | programmed cell death 10 (PDCD10) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16564356 | AC092073.1 | novel protein, readthrough between GPI and PDCD2 | ENCODES a protein that exhibits carbohydrate derivative binding (inferred); glucose-6-phosphate isomerase activity (inferred); INVOLVED IN carbohydrate derivative metabolic process (inferred); gluconeogenesis (inferred); glycolytic process (inferred) | | | | Human | 5 | name | gene, protein-coding |
| 1605963 | VSIR | V-set immunoregulatory receptor | Enables endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of metabolic process; and regulation of T cell activation. Located in plasma membrane. [ provided by Alliance of Genome Resources, Jul 2025] | 10 | 71747556 | 71773520 | Human | 109 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 16564396 | LOC124904695 | uncharacterized LOC124904695 | | 19 | 34426106 | 34428364 | Human | | old_gene_name | gene, ncrna, MODEL [RefSeq] |
| 1320409 | CHMP4B | charged multivesicular body protein 4B | This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors i nto multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq, Oct 2009] | 20 | 33811348 | 33854366 | Human | 187 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1606816 | LILRA4 | leukocyte immunoglobulin like receptor A4 | This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3) . This gene is one of a cluster of highly related genes located at chromosomal region 19q13.4. [provided by RefSeq, Jan 2015] | 19 | 54333185 | 54339162 | Human | 30 | description | gene, protein-coding, REVIEWED [RefSeq] |
